Results 31 to 40 of about 100,119 (262)

The Coal Pillar Width Effect of Principal Stress Deflection and Plastic Zone Form of Surrounding Rock Roadway in Deep Excavation

open access: yesGeofluids, 2022
In order to explore the influence of coal pillar width on the principal stress deflection and plastic zone form of surrounding rock in deep roadway excavation, taking 11030 working face transportation roadway of Zhaogu No.
Ji Li, Rongguang Zhang, Xubo Qiang
doaj   +1 more source

Theoretical Study of the Evolution Characteristics of the Plastic Deformation Zone of Type I–II Composite Fractured Rock under Osmotic Pressure

open access: yesApplied Sciences
The coupled seepage–stress action has a significant deterioration effect on the structural face of the hydraulic tunnel enclosure, which intensifies the shear rupture tendency of the deteriorated structural face of the rock mass.
Zelin Niu   +3 more
doaj   +1 more source

Approximate solution of plastic zone in surrounding rock under three-dimensional stress field based on Drucker-Prager strength criterion

open access: yes矿业科学学报
This study proposes to address the stability of roadway surrounding rock under three-dimensional stress field based on the Drucker-Prager criterion and the theory of elastic-plastic mechanics.
LIU Hongtao   +4 more
doaj   +1 more source

Research on large deformation mechanism of deep roadway with dynamic pressure

open access: yesEnergy Science & Engineering, 2020
In this paper, the large deformation mechanism of deep dynamic pressure roadway is studied from the perspective of the formation and development of plastic zone, and creep and damage of rock mass.
Lei Fan   +3 more
doaj   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Glial plasticity at nervous system transition zones

open access: yesBiology Open, 2023
ABSTRACT The central and peripheral nervous systems (CNS and PNS, respectively) are two separate yet connected domains characterized by molecularly distinct cellular components that communicate via specialized structures called transition zones to allow information to travel from the CNS to the periphery, and vice versa.
openaire   +3 more sources

Construction Method of Honeycomb Gas Flow Network Channel: Structure-Based and Engineering Response on Plastic Zone Distribution Form

open access: yesApplied Sciences, 2023
The plastic zone of the surrounding rock of the borehole is a high-quality channel for gas flow. Studying the distribution form of the plastic zone in the surrounding rock of the boreholes and the characteristics of the extended connection network is ...
Chao Yuan   +4 more
doaj   +1 more source

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Analysis of Surrounding Rock Pressure of Deep Buried Tunnel considering the Influence of Seepage

open access: yesGeofluids, 2022
This paper takes the surrounding rock of deep tunnel as the research object and considers the action mechanism under the influence of seepage. Based on the Mohr-Coulomb criterion, the stress mechanism of surrounding rock of deep buried tunnel is analyzed
Qingchen Yao   +5 more
doaj   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

open access: yesMolecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho   +2 more
wiley   +1 more source

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