Results 41 to 50 of about 544,820 (302)

Research on large deformation mechanism of deep roadway with dynamic pressure

Energy Science & Engineering, 2020
In this paper, the large deformation mechanism of deep dynamic pressure roadway is studied from the perspective of the formation and development of plastic zone, and creep and damage of rock mass.
Lei Fan, Weijun Wang, Chao Yuan, Wenqing Peng   +3 more
doaj   +1 more source

Analysis of Surrounding Rock Pressure of Deep Buried Tunnel considering the Influence of Seepage

Geofluids, 2022
This paper takes the surrounding rock of deep tunnel as the research object and considers the action mechanism under the influence of seepage. Based on the Mohr-Coulomb criterion, the stress mechanism of surrounding rock of deep buried tunnel is analyzed
Qingchen Yao, Yukun Ma, Zongyang Xiao, Zudi Zhang, Yaxin Lu, Chenyang Liu   +5 more
doaj   +1 more source

Feasibility and Preliminary Efficacy of Integrative Neuromuscular Training for Childhood Cancer Survivors: A Pilot Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Survivors of childhood acute lymphoblastic leukemia (ALL) often exhibit early deficits in muscle and movement competence, which can compromise long‐term health. Integrative neuromuscular training (INT), a multifaceted approach combining fundamental movement activities with strength exercises, may help address these deficits during ...
Anna Maria Markarian, Robert U. Newton, Dennis R. Taaffe, Nicholas G. Gottardo, Santosh Valvi, Carolyn J. Peddle‐McIntyre, Jodie Cochrane Wilkie, Daniel A. Galvão   +7 more
wiley   +1 more source

Theoretical Study of the Evolution Characteristics of the Plastic Deformation Zone of Type I–II Composite Fractured Rock under Osmotic Pressure

Applied Sciences
The coupled seepage–stress action has a significant deterioration effect on the structural face of the hydraulic tunnel enclosure, which intensifies the shear rupture tendency of the deteriorated structural face of the rock mass.
Zelin Niu, Yun Cheng, Jiafeng Pei, Tian Xu   +3 more
doaj   +1 more source

Construction Method of Honeycomb Gas Flow Network Channel: Structure-Based and Engineering Response on Plastic Zone Distribution Form

Applied Sciences, 2023
The plastic zone of the surrounding rock of the borehole is a high-quality channel for gas flow. Studying the distribution form of the plastic zone in the surrounding rock of the boreholes and the characteristics of the extended connection network is ...
Chao Yuan, Lian-Xin Li, Lei Fan, Yue-Yang Xu, Jun-Jie Wu   +4 more
doaj   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Linear Stability Analysis for Plane-Poiseuille Flow of an Elastoviscoplastic fluid with internal microstructure [PDF]

, 1997
We study the linear stability of Plane Poiseuille flow of an elastoviscoplastic fluid using a revised version of the model proposed by Putz and Burghelea (Rheol. Acta (2009)48:673-689).
Moyers-Gonzalez, Miguel, Burghelea, Teodor, Mak, Julian   +2 more
core   +7 more sources

Experimental study of surface cracks [PDF]

, 1972
Analysis of plastic zones surrounding surface cracks in stressed steel and titanium plates subjected to tensile loading shows that back surface dimpling develops at stress levels considerably lower than those predicted by theoretical models of yield zone

core   +1 more source

Slow crack growth in polycarbonate films [PDF]

, 2005
We study experimentally the slow growth of a single crack in polycarbonate films submitted to uniaxial and constant imposed stress. The specificity of fracture in polycarbonate films is the appearance of flame shaped macroscopic process zones at the tips
, Barenblatt G. I., L Vanel, P. P Cortet, S Ciliberto, S Santucci, Santucci S., Stojimirovic A., Zhurkov S. N.   +8 more
core   +5 more sources

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source