Results 41 to 50 of about 1,580 (218)

Plasticizing performance and biological safety of multi-green-component plasticizers for PVC

open access: yesPolymer Testing
Plasticizers are crucial additives for poly (vinyl chloride) (PVC) processing. However, conventional phthalate-based plasticizers suffer from high migration rates and significant toxicity.
Bingfeng Qian   +6 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Biodegradable polymer materials and modifying additives: state of the art. Part I.

open access: yesНанотехнологии в строительстве, 2020
One of the most demanded materials on the planet is plastic, the excellent performance of which contributes to the accumulation of a significant amount of waste on its basis.
Irina N. Vikhareva
doaj   +1 more source

Effects of Plasticizing on Mechanical and Viscous Characteristics of Poly(vinyl alcohol): A Comparative Study between Glycerol and Diethanolamine

open access: yesMacromolecular Materials and Engineering, 2023
Although plasticizing materials by modification with small‐molecular chemicals has been extensively utilized in the industrial community, processing poly(vinyl alcohol) (PVA) at high concentrations (CPVA) or with a high degree of polymerization (DP ...
Yihang Yao   +3 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Estudo do uso de plastificantes de fontes renovável em composições de PVC Study of the use of plasticizer from renewable sources in PVC compositions

open access: yesPolímeros, 2009
Polímeros sintéticos são largamente utilizados em diversos produtos devido às suas propriedades físicas, químicas e facilidade de transformação. O poli(cloreto de vinila), conhecido como PVC, é um dos polímeros mais versáteis desenvolvidos pelo homem, de
Emerson Madaleno   +4 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Unveiling the mechanistic links between plasticizers and gastric cancer via network toxicology and molecular docking approaches

open access: yesBMC Pharmacology and Toxicology
Background This study explores the potential molecular mechanisms underlying the pathogenesis of gastric cancer induced by plasticizers, with particular emphasis on the interactions between plasticizers and key genes and signaling pathways.
Rui Guo   +7 more
doaj   +1 more source

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