Results 51 to 60 of about 26,860 (262)

Effects of Plasticizing on Mechanical and Viscous Characteristics of Poly(vinyl alcohol): A Comparative Study between Glycerol and Diethanolamine

Macromolecular Materials and Engineering, 2023
Although plasticizing materials by modification with small‐molecular chemicals has been extensively utilized in the industrial community, processing poly(vinyl alcohol) (PVA) at high concentrations (CPVA) or with a high degree of polymerization (DP ...
Yihang Yao, Zhenjie Zhang, Ke Wang, Qiang Fu   +3 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Estudo do uso de plastificantes de fontes renovável em composições de PVC Study of the use of plasticizer from renewable sources in PVC compositions

Polímeros, 2009
Polímeros sintéticos são largamente utilizados em diversos produtos devido às suas propriedades físicas, químicas e facilidade de transformação. O poli(cloreto de vinila), conhecido como PVC, é um dos polímeros mais versáteis desenvolvidos pelo homem, de
Emerson Madaleno, Derval dos S. Rosa, Sonia F. Zawadzki, Tiago H. Pedrozo, Luiz P. Ramos   +4 more
doaj   +1 more source

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

Organophosphate in Niederschlag, stehenden Oberflächengewässern und Grundwasser städtischer sowie abgelegener Gebiete [PDF]

, 2010
Within the present study the occurrence and fate of the organophosphorus flame retardants and plasticizers tris(2-chloroethyl) phosphate (TCEP), tris(2-chloro-1-methylethyl) phosphate (TCPP), tris(1,3-dichloro-2-propyl) phosphate (TDCP), tris(2 ...
Regnery, Julia
core  

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Unveiling the mechanistic links between plasticizers and gastric cancer via network toxicology and molecular docking approaches

BMC Pharmacology and Toxicology
Background This study explores the potential molecular mechanisms underlying the pathogenesis of gastric cancer induced by plasticizers, with particular emphasis on the interactions between plasticizers and key genes and signaling pathways.
Rui Guo, Weifeng Ma, Zhi Ren, Dapeng Li, Meng Wang, Mingtao Xu, Hailun Zheng, Xiquan Ke   +7 more
doaj   +1 more source

Investigation of potential migratables from paper and board food contact materials

Frontiers in Chemistry, 2023
Since the ban on single-use plastic articles in Europe, the food contact material (FCM) industry has been forced to move to more sustainable alternatives. Paper and board FCM are convenient alternatives but must be safe for consumers.
Mélanie Di Mario, Gregory Bauwens, Florian Peltier, Séverine Goscinny, Jean-François Focant, Giorgia Purcaro, Els Van Hoeck   +6 more
doaj   +1 more source

Plasticizers Derived from Biomass Resources: A Short Review

, 2018
With rising environmental concerns and depletion of petrochemical resources, biomass-based chemicals have been paid more attention. Polyvinyl chloride (PVC) plasticizers derived from biomass resources (vegetable oil, cardanol, vegetable fatty acid ...
Kehan Tang, Puyou Jia, Yonghong Zhou, Haoyu Xia   +3 more
core   +1 more source