Results 101 to 110 of about 1,184,204 (373)

Hemodialysis membrane-related neutrophil dysfunctions and pentoxifylline - a pilot study [PDF]

, 1990
Hemodialysis treatment is associated with activation of neutrophil granulocytes. Pentoxifylline has been shown to inhibit neutrophil activation in vitro and in vivo.
Hoffmann, H., Jochum, Marianne, Schiffl, H., Spannagl, Michael   +3 more
core   +1 more source

Characterization of a platelet-activating factor receptor antagonist isolated from haifenteng (Piper futokadsura): specific inhibition of in vitro and in vivo platelet-activating factor-induced effects.

Proceedings of the National Academy of Sciences of the United States of America, 1985
Platelet-activating factor (PAF) is a potent lipid mediator of inflammation and asthma. Using a receptor preparation of rabbit platelet membranes, we identified a novel antagonist of PAF in the methylene chloride extract of a Chinese herbal plant ...
T. Shen, S. Hwang, M. N. Chang, T. Doebber, M. Lam, M. Wu, X. Wang, G. Han, R. Li   +8 more
semanticscholar   +1 more source

The Potential for Extracellular Vesicles in Nanomedicine: A Review of Recent Advancements and Challenges Ahead

Advanced Biology, EarlyView.
Extracellular vesicles (EVs) play a dual role in diagnostics and therapeutics, offering innovative solutions for treating cancer, cardiovascular, neurodegenerative, and orthopedic diseases. This review highlights EVs’ potential to revolutionize personalized medicine through specific applications in disease detection and treatment.
Farbod Ebrahimi, Anjali Kumari, Samaneh Ghadami, Saqer Al Abdullah, Kristen Dellinger   +4 more
wiley   +1 more source

Novel molecular analogues of phosphatidylcholines in a lipid extract from bovine brain: 1-long-chain acyl-2-short-chain acyl-sn-glycero-3-phosphocholines.

Journal of Lipid Research, 1989
A vasodepressor phospholipid fraction named Depressor-IA from a bovine brain lipid extract was analyzed by capillary gas-liquid chromatography-mass spectrometry as tert-butyldimethylsilyl derivatives after hydrolysis with phospholipase C.
A Tokumura, K Takauchi, T Asai, K Kamiyasu, T Ogawa, H Tsukatani   +5 more
doaj  

The Infinite Hierarchical Factor Regression Model [PDF]

NIPS 2008, 2009
We propose a nonparametric Bayesian factor regression model that accounts for uncertainty in the number of factors, and the relationship between factors. To accomplish this, we propose a sparse variant of the Indian Buffet Process and couple this with a hierarchical model over factors, based on Kingman's coalescent. We apply this model to two problems (
arxiv  

Staphylococcus aureus lipoteichoic acid inhibits platelet activation and thrombus formation via the Paf receptor [PDF]

, 2013
Impaired healing is common in wounds infected with the major human pathogen Staphylococcus aureus, although the underlying mechanisms are poorly understood.
Amatruda, Ames, Amie K. Waller, Brown, Christopher Kumar, Clark, Corrigan, Deo, Draing, Dupré, Fedtke, Fischer, Fitzgerald, Haribabu, Hashimoto, Hwang, Iwasaki, Jonathan M. Gibbins, Kengatharan, Li, Lotz, Madsen, Mazer, Miajlovic, Moraes, Morath, Murphy, Nick, Peschel, Que, Reichmann, Rowley, Schmaler, Schröder, Schwarz, Shannon, Sheu, Siboo, Simon R. Clarke, Smyth, Stoll, Tanya Sage, Thomas Carr, Travers, van Langevelde, Vinogradov, Vogensen, Voorhees, Weidenmaier, Weidenmaier, Ye, Yeaman, Youssefian, Yue, Zhang, Zhang   +55 more
core   +1 more source

Murine Models and Human Cell Line Models to Study Altered Dynamics of Ovarian Follicles in Polycystic Ovary Syndrome

Advanced Biology, EarlyView.
The manuscript examines preclinical murine and human models to study polycystic ovary syndrome (PCOS), delving into the cellular and molecular mechanisms underlying altered ovarian follicular dynamics. It explores the cellular interactions involved in normal and PCOS ovaries and outlines the current and novel strategies in the search for preclinical ...
Arturo Bevilacqua, Cristiano Giuliani, Giovanna Di Emidio, Samuel H Myers, Vittorio Unfer, Carla Tatone   +5 more
wiley   +1 more source

New Pivot Selection for Sparse Symmetric Indefinite Factorization [PDF]

arXiv, 2016
We propose a new pivot selection technique for symmetric indefinite factorization of sparse matrices. Such factorization should maintain both sparsity and numerical stability of the factors, both of which depend solely on the choices of the pivots. Our method is based on the minimum degree algorithm and also considers the stability of the factors at ...
arxiv  

Involvement of Platelet-Activating Factor in Ultraviolet B-Induced Hyperalgesia [PDF]

, 2009
Ultraviolet B (UVB) radiation causes cutaneous inflammation. One important clinical consequence of UVB-induced inflammation is increased pain or hyperalgesia, which is likely mediated by enhanced sensitivity of cutaneous sensory neurons. Previous studies
Al-Hassani, Mohammad, Cai, Shanbao, Hingtgen, Cynthia M., Pollok, Karen E., Sitzman, Leslie A., Travers, Jeffrey B., Zhang, Qiwei   +6 more
core   +1 more source

Revealing the γ′ and γ″ Phase Fractions of Additively Manufactured and Differently Heat‐Treated Nickel‐Base Superalloy IN718 by Atom Probe Tomography and Their Impact on Mechanical Properties

Advanced Engineering Materials, EarlyView.
Additive manufacturing is a promising route for the production of Ni‐base superalloys for turbine applications, such as Inconel 718. Nonetheless, it induces various changes in the microstructure and performance of these materials. One such change is the incidence of the δ‐Ni3Nb phase, whose impact on microstructure, aging precipitate fractions, and ...
Guilherme Maziero Volpato, Jan Vollhüter, Benedikt Diepold, Martin Sebastian Meier, Martin Pröbstle, Mathias Göken, Thomas Niendorf, Peter Felfer, Steffen Neumeier   +8 more
wiley   +1 more source