Polar lipids modify Alzheimer's Disease pathology by reducing astrocyte pro-inflammatory signaling through platelet-activating factor receptor (PTAFR) modulation. [PDF]
Hans S +8 more
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Investigation of the involvement of platelet-activating factor in the control of hypertension by aerobic training. A randomized controlled trial. [PDF]
Prado JP +8 more
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Platelet Activating Factor Receptor and Intercellular Adhesion Molecule-1 Expression Increases in the Small Airway Epithelium and Parenchyma of Patients with Idiopathic Pulmonary Fibrosis: Implications for Microbial Pathogenesis. [PDF]
Shahzad AM +11 more
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[Relationship Between Neonatal Outcomes and Changes in Serum Platelet-Activating Factor, Fibulin-3, and Umbilical Artery Blood Flow During Late Pregnancy in Pregnant Women With Gestational Hypertension]. [PDF]
Sun Y, Zhang H, Sun L.
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Associations between healthy food groups and platelet-activating factor, lipoprotein-associated phospholipase A2 and C-reactive protein: a cross-sectional study. [PDF]
English CJ +5 more
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Severe Type 2 Inflammation Leads to High Platelet-Activating-Factor-Associated Pathology in Chronic Rhinosinusitis with Nasal Polyps-A Hierarchical Cluster Analysis Using Bulk RNA Barcoding and Sequencing. [PDF]
Ishino T +10 more
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Platelet-activating factor antagonists
Clinical Reviews in Allergy, 1995The great number of PAF antagonists reviewed in this article clearly shows the tremendous effort made in the last 20 yr to explore the complex biological background of the mechanism of action of PAF and the potential clinical benefit of its antagonists. It is obvious that now highly potent, long-acting, and perorally applicable PAF-receptor antagonists
M, Koltai, P G, Braquet
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Platelet-activating factor (PAF) is a potent mediator that occurs at very low concentrations in cells and tissues. Accurate quantitation of PAF has always been difficult because of the physicochemical properties of PAF and its structural similarity to several much more abundant phospholipids.
John S, Owen +2 more
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