RGS10 shapes the hemostatic response to injury through its differential effects on intracellular signaling by platelet agonists. [PDF]
Platelets express ≥2 members of the regulators of G protein signaling (RGS) family. Here, we have focused on the most abundant, RGS10, examining its impact on the hemostatic response in vivo and the mechanisms involved.
Brass, Lawrence F.+7 more
core +1 more source
Tannic acid‐selenocystamine (TA‐SeCA) nanocoating enables stable, sustained catalytic nitric oxide (NO) release on catheter surfaces. This one‐step phenol‐amine coating improves catheter functionality by enhancing endogenous NO production, supporting vascular function, and reducing inflammation.
Qingqing Fan+7 more
wiley +1 more source
Positive association between schizophrenia and rheumatoid arthritis
Background: An inverse relationship is observed between schizophrenia and rheumatoid arthritis (RA). Case description: A 33 years old male patient's case history is discussed for an unusual co-occurrence of schizophrenia and rheumatoid arthritis ...
Anil Kumar+3 more
doaj
IL-1 and related cytokines enhance thrombin-stimulated PGI2 production in cultured endothelial cells without affecting thrombin-stimulated von Willebrand factor secretion or platelet-activating factor biosynthesis. [PDF]
George B. Zavoico+3 more
openalex +1 more source
Plasma oxidation following polydopamine deposition can significantly reduce the surface hydrophobicity of polyurethane‐siloxanes without impacting surface roughness, thereby increasing fibroblast viability, adhesion, and extracellular matrix production and secretion.
Sophie Armstrong+5 more
wiley +1 more source
Platelet receptor-mediated factor X activation by factor IXa. High-affinity factor IXa receptors induced by factor VIII are deficient on platelets in Scott syndrome. [PDF]
Syed S. Ahmad+3 more
openalex +1 more source
This study develops a 3D vascular injury model using a microphysiological system that mimics key features of intimal hyperplasia. Antiproliferative drugs reduced VSMC proliferation but worsened endothelialdenudation. A combination of diphenyleneiodonium and quercetin effectively reduced proliferation and migration of VSMC and inflammation while ...
Ungsig Nam+7 more
wiley +1 more source
Role of micronutrients in the modulation of immune system and platelet activating factor in patients with COVID-19; a narrative review. [PDF]
Doaei S, Mardi A, Zare M.
europepmc +1 more source
Phospholipase D activation by the mitogens platelet‐derived growth factor and 12‐O‐tetradecanoylphorbol 13‐acetate in NIH‐3T3 cells [PDF]
Pazit Ben-Av, Mordechai Liscovitch
openalex +1 more source
Lymphoid and CXCR4 Cell Targeted Lipid Nanoparticles Facilitate HIV‐1 Proviral DNA Excision
Advancements in ART improve HIV‐1 patient outcomes but are unable to eliminate latent viral DNA. To address this, CXCR4‐targeted lipid nanoparticles (T‐LNPs) for delivering CRISPR‐Cas9 to excise HIV‐1 DNA in infected cells are developed. These T‐LNPs achieve ≈60% HIV‐1 DNA excision efficacy in blood and splenic tissue, demonstrating promise for ...
Sudipta Panja+6 more
wiley +1 more source