Results 311 to 320 of about 192,462 (340)
Some of the next articles are maybe not open access.
Platelet-Activating Factor and Platelet-Activating Factor Antagonists in Acute Pancreatitis
Digestive Surgery, 1999<i>Introduction:</i> Acute pancreatitis causes platelet-activating factor (PAF) to be released which induces systemic effects that contribute to circulatory disturbances and multiple organ failure. PAF has also been implicated as a key mediator in the progression of severe acute pancreatitis, which can lead to complications and unacceptably
openaire +2 more sources
2000
Research leading to the discovery of platelet-activating factor (PAF) came from studying a reaction that triggered platelets to release histamine. It was attributed to a factor actively released from leukocytes. Platelet-activating factor was first identified by Benveniste et al. in 1972.1 Later it was recognized that this phospholipid mediator is also
W. A. Buurman +3 more
openaire +2 more sources
Research leading to the discovery of platelet-activating factor (PAF) came from studying a reaction that triggered platelets to release histamine. It was attributed to a factor actively released from leukocytes. Platelet-activating factor was first identified by Benveniste et al. in 1972.1 Later it was recognized that this phospholipid mediator is also
W. A. Buurman +3 more
openaire +2 more sources
Platelet Activating Factor and Conception
American Journal of Reproductive Immunology, 1996PURPOSE: This review provides evidence for the involvement of platelet activating factor (PAF) in the several facets of pregnancy establishment.METHODS: A comprehensive literature review and new data.RESULTS: PAF has a role in spermatozoal function, fertilization, embryo development, and implantation.CONCLUSIONS: PAF is intimately involved in ...
N. Gleicher +5 more
openaire +3 more sources
Revue Française d'Allergologie et d'Immunologie Clinique, 1977
Resume Il existe dans les basophiles et les mastocytes de nombreuses especes de mammiferes un facteur agregeant les plaquettes qui represente par consequent un lien entre la pathologie liee a la degranulation des basophiles/mastocytes, c'est-a-dire l'hypersensibilite immediate, et les plaquettes sanguines.
openaire +2 more sources
Resume Il existe dans les basophiles et les mastocytes de nombreuses especes de mammiferes un facteur agregeant les plaquettes qui represente par consequent un lien entre la pathologie liee a la degranulation des basophiles/mastocytes, c'est-a-dire l'hypersensibilite immediate, et les plaquettes sanguines.
openaire +2 more sources
Platelet-Activating Factor Antagonists
Annual Review of Pharmacology and Toxicology, 1987Over the past decade platelet-activating factor has achieved the status of an important inflammatory mediator. The scientific enthusiasm and number of research investigators, publications, and meetings recently devoted to PAF suggest that this mediator will be the subject of continued study in the foreseeable future.
R N Saunders, D A Handley
openaire +3 more sources
Platelet Activating Factor Receptors
2003Platelet activating factor (PAF) is a potent pro-inflammatory lipid mediator. Its effects are mediated through cell surface G protein-coupled receptors (GPCRs) that are distributed on numerous cells notably on endothelium [1]. An intracrine mode of action for PAF is proposed based on evidence for intracellular PAF binding sites [2] and retention of ...
Sanaa Choufani +15 more
openaire +3 more sources
Seminal Platelet-Activating Factor
Seminars in Thrombosis and Hemostasis, 2007Platelet-activating factor (PAF; 1-O-alkyl-2-O-acetyl-sn-glycero-3-phosphorylcholine) is a potent signaling phospholipid with pleiotropic biologic activities. Since its discovery more than 30 years ago, numerous investigators have documented its presence in a variety of tissues.
openaire +3 more sources
Synthesis of platelet-activating factor by human monocytes stimulated by platelet-activating factor
Journal of Allergy and Clinical Immunology, 1991The capacity of platelet-activating factor (PAF) to stimulate its own synthesis by human monocytes was examined. Adherent human monocytes of greater than 85% purity were incubated with 100 fM to 10 nM of PAF in the presence of 20 microCi of [3H]acetic acid to radiolabel newly synthesized PAF.
Frank H. Valone, Frank H. Valone
openaire +3 more sources
1995
Platelet activating factor (PAF) is a low molecular weight, ether-linked phospholipid originally identified as a soluble factor, released from sensitized rabbit basophils during IgE anaphylaxis, that was capable of aggregating rabbit platelets [1, 2]. Cellular sources of PAF subsequently identified include neutrophil [3–8] and eosinophil granulocytes ...
openaire +2 more sources
Platelet activating factor (PAF) is a low molecular weight, ether-linked phospholipid originally identified as a soluble factor, released from sensitized rabbit basophils during IgE anaphylaxis, that was capable of aggregating rabbit platelets [1, 2]. Cellular sources of PAF subsequently identified include neutrophil [3–8] and eosinophil granulocytes ...
openaire +2 more sources
Platelet-activating factor in human endometrium
The Journal of Steroid Biochemistry and Molecular Biology, 1994Platelet-activating factor (PAF) is a phospholipid actively produced by human endometrium and deeply involved in the processes of ovoimplantation and labor. We recently found that PAF represents a new autocrine growth factor for a human adenocarcinoma cell line, HEC-1A.
BALDI, ELISABETTA +8 more
openaire +5 more sources