Results 161 to 170 of about 32,823 (297)

ALOX15 mediates thrombin‐induced myristoylation, trafficking, and interaction of protease‐activated receptors, leading to platelet activation and hemostasis

The FEBS Journal, EarlyView.
The role of PARs in platelet function is fairly known; however, the underlying mechanisms are not fully understood. We report that thrombin myristoylates PAR4 in mouse platelets and PAR1 and PAR4 in human platelets, facilitating their membrane transport and interaction, leading to PAR3/4 heterodimers in mice and PAR1/4 heterodimers in humans.
Suresh Govatati, Chandra Sekhar Yadavalli, Md Monirul Hoque, Swapna Thota, Gadiparthi N. Rao   +4 more
wiley   +1 more source

Regenerative Endodontics in Teeth With Irreversible Pulpitis: A Scoping Review

International Endodontic Journal, EarlyView.
ABSTRACT Introduction Regenerative endodontic procedures (REPs) have been widely used to manage a range of pulpal pathologies, particularly in immature permanent teeth. The development of bioactive calcium silicate–based materials has led to a paradigm shift in vital pulp therapy (VPT) and REPs.
Mahmoud Torabinejad, Neda Najafimakhsoos, George Bogen   +2 more
wiley   +1 more source

Platelet-Rich Fibrin (PRF) Analyzed for Cytokine Profiles - A Misguided Hope for Osteogenesis in Jawbone Defects? Research and Clinical Observational Study [PDF]

Johann Lechner,1 Volker vonBaehr,2 Cornelia Doebis,3 Florian Notter,4 Fabian Schick4 1Department of Osteoimmunology, Clinic for Integrative Dentistry, Munich, Germany; 2Department of Immunology and Allergology, Institute for Medical Diagnostics, Berlin ...
Lechner J, Doebis C, Notter F, Schick F, vonBaehr V   +4 more
core   +1 more source

Management of Periodontal Abscesses and Endodontic‐Periodontal Lesions—A Systematic Review

Journal of Clinical Periodontology, EarlyView.
ABSTRACT Aim To evaluate the management of periodontal abscesses and endodontic‐periodontal lesions (EPLs). Methods Seven focused questions addressed outcomes such as pocket depth (PD), bleeding on probing (BOP), tooth loss or ovoid elevation. The literature search covered three electronic databases and manual sources for intervention studies.
Henrik Dommisch, Daniela Hoedke, Marina Dourou, Elena Calciolari, David Herrera, Selena Toma   +5 more
wiley   +1 more source

Management of Non‐Plaque‐Induced Gingival Conditions: A Systematic Review—Part 2: Inflammatory and Immune Conditions; Neoplasms; and Gingival Pigmentation

Journal of Clinical Periodontology, EarlyView.
ABSTRACT Aims This systematic review assesses current evidence on the management of non‐plaque (dental biofilm)‐induced gingival diseases and conditions (NPIGDs), including (i) inflammatory and immune conditions, (ii) neoplasms and (iii) gingival pigmentations.
Maria Clotilde Carra, Cecile Wasielewski, Bruno Špiljak, Maja Sabalić‐Schoener, Sebastien Jungo, Ivan Alajbeg   +5 more
wiley   +1 more source

Long‐Term Clinical and Radiographic Outcomes of Ceramic Dental Implants: An 11‐Year Retrospective Cohort Study

Journal of Esthetic and Restorative Dentistry, EarlyView.
ABSTRACT Objective Evidence on zirconia dental implants remains limited. This retrospective study evaluated clinical and radiographic outcomes of contemporary ceramic implant systems placed in private practice with variable follow‐up of up to 11 years.
Mona Monzavi, Medis Masnavi, Ayman Zraiqat, Al Manesh   +3 more
wiley   +1 more source

Use of Platelet‐Rich Fibrin (PRF) on Palatal Wound Healing: A Narrative Review With Clinical Recommendations

Journal of Periodontal Research, EarlyView.
Based on the available evidence, the application of platelet‐rich fibrin (PRF) following free gingival graft (FGG) and subepithelial connective tissue graft (SCTG) harvesting appears to be a promising approach for enhancing wound healing, minimizing postoperative complications, and reducing analgesic consumption. ABSTRACT This clinical narrative review
Nima Farshidfar, Paras Ahmad, Nathan Estrin, Yufeng Zhang, Richard J. Miron   +4 more
wiley   +1 more source

Biomaterials for Reconstructive Treatment of Peri‐Implantitis

Journal of Periodontal Research, EarlyView.
Reconstructive therapy should be implemented in contained defects. Various bone filler materials with or without a barrier membrane and/or adjunctive biologics may be applied. ABSTRACT Peri‐implantitis is a pathological condition affecting the tissues surrounding dental implants, marked by inflammation of the peri‐implant connective tissue and ...
Ausra Ramanauskaite, Anton Sculean, Emilio A. Cafferata, Frank Schwarz   +3 more
wiley   +1 more source

Membranes for Periodontal and Bone Regeneration: Everything You Need to Know

Journal of Periodontal Research, EarlyView.
This paper presents and highlights a summary of the past, present, and future of membranes for oral regeneration in clinical applications and fundamental studies. ABSTRACT Implant dentistry and periodontology have shown an increasing demand for regenerative procedures associated with biomaterials targeting successful clinical outcomes and predictable ...
Marcel F. Kunrath, Gabriel L. Magrin, Candida S. Zorzo, Ingrid Rigotto, Hanna Aludden, Christer Dahlin   +5 more
wiley   +1 more source

Harnessing the Therapeutic Potential of Cell Secretomes and Extracellular Vesicles for Craniofacial Regenerative Applications

Journal of Periodontal Research, EarlyView.
The scoping review summarizes the current preclinical and clinical evidence for the use of “cell‐free” therapies in craniofacial (periodontal, bone and soft‐tissue) regeneration. It also aims to highlight key challenges and strategies towards the clinical translation of these therapies.
Siddharth Shanbhag, Magdalena Mayol, Danijel Domic, Madhusudhan Reddy Bobbili, Johannes Grillari, Mariano Sanz, Reinhard Gruber   +6 more
wiley   +1 more source