Results 1 to 10 of about 16,295 (299)
Evaluating platelet concentrates by platelet indices, thromboelastography, and flow cytometry
INTRODUCTION: Platelet transfusion has been therapeutically used in patients with thrombocytopenia and platelet function defects over the years. The use of advanced techniques may add value in assessing the quality of platelet products.
Tapasyapreeti Mukhopadhyay +6 more
doaj +2 more sources
Evaluation of platelet aggregation in platelet concentrates: storage implications
The use of hemo-derivatives is nowadays a fundamentally important therapeutic modality in the exercise of medicine. Among the various hemo-components employed, we have the platelet concentrate (PC), indicated in cases of hemorrhagic disturbances.
Neiva Teresinha J.C. +6 more
doaj +1 more source
Factors Affecting Platelet Concentration in Platelet Concentrates from Canine Blood Donors
Abstract Background Physiologic factors in dogs that might contribute to enhanced platelet yield in platelet concentrates (PCs) are largely unknown. Objective To determine whether individual differences in weight, age,
J.S. Raleigh +3 more
openaire +4 more sources
Quality assessment of the preparation and storage of leukocyte-depleted pooled platelet concentrates
Objective: To explore the feasibility of using a disposable platelet storage bag containing a leukocyte filter to prepare leukocyte-depleted pooled platelet concentrates with the buffy coat method.Methods: 150 bags of whole blood samples (400 mL/bag ...
Feng Chen +4 more
doaj +1 more source
Platelet factor 4 in platelet concentrates.
The release of platelet factor 4 (PF4) from platelets in platelet concentrates (PC) were investigated sequentially in the process of blood collection, and their storage at room temperature for up to 72h with agitation. No appreciable increase in PF4 release was seen immediately after blood collection.
Ishikawa, Yuko +7 more
openaire +2 more sources
Metabolism of Platelet 5-Hydroxytryptamine in Acidified Platelet Concentrates
The present study was designed to understand the metabolism of 5-hydroxytryptamine (serotonin, 5HT), a dense granule constituent of platelets, in acidified platelet concentrates (PC) during in vitro storage in polyvinylchloride plastic containers at 22 degrees C.
SHIMIZU, Tetsuo, KOUKETSU, Keiko
openaire +2 more sources
Objective To investigate the feasibility of leucocyte-reduced pooled platelet concentrates from whole blood stored at 4℃, and provide theoretical basis for the components preparation.
Huijuan AN +7 more
doaj +1 more source
INTRODUCTION: For many years, platelet concentrates have been used for the prevention as well as treatment of bleeding disorders, especially in those patients with haematological problems involving platelet disorders as well as refractoriness, In ...
Nancy Wanjiru Thuku +2 more
doaj +1 more source
Immune interactions and regulation with CD39+ extracellular vesicles from platelet concentrates
IntroductionCD39 plays an important role in the immunoregulation and inhibition of effector cells. It is expressed on immune cells, including Tregs, and on extracellular vesicles (EVs) budding from the plasma membrane.
Adèle Silane Delorme +27 more
doaj +1 more source
The Effect of Leukocyte Removal and Matrix Metalloproteinase Inhibition on Platelet Storage Lesions
The reasons for unfavorable changes in platelet concentrate (PC) quality during storage are not fully understood yet. We aimed to evaluate whether leukocytes and matrix metalloproteinases (MMPs) lead to a decrease in the quality of PCs and examine ...
Alina Rak-Pasikowska +6 more
doaj +1 more source

