Platelet aggregation and quality control of platelet concentrates produced in the Amazon Blood Bank [PDF]
BACKGROUND: The study of platelet aggregation is essential to assess in vitro platelet function by different platelet activation pathways. OBJECTIVE: To assess aggregation and biochemical parameters of random platelet concentrates produced at the ...
Maria José Dantas Coêlho +6 more
doaj +2 more sources
Comparative evaluation of platelet count and antimicrobial efficacy of injectable platelet-rich fibrin with other platelet concentrates: An in vitro study [PDF]
Background: Platelet concentrates are used in various medical procedures to promote soft- and hard-tissue regeneration. In recent times, their antimicrobial efficacy is also explored.
Prerna Ashok Karde +5 more
doaj +2 more sources
Evaluation of the quality of platelet concentrates obtained in a Peruvian hospital [PDF]
Introduction Platelet concentrates are blood products obtained from donor’s blood, and their conservation must be subject to a strict quality control process to guarantee a safe and high-performance product in treating diseases that require their use.
Jair Huamani-Chacchi +2 more
doaj +2 more sources
Comparison of Platelet Counting Technologies in Equine Platelet Concentrates [PDF]
Objective(1) To compare the performance of 4 platelet counting technologies in equine platelet concentrates and (2) to evaluate the ability of the Magellan platelet rich plasma (PRP) system to concentrate equine platelets.Study DesignExperimental study to assess method agreement.AnimalsAdult mixed breed horses (n = 32).MethodsAcid citrate dextrose‐A ...
Caitlin M, O'Shea +2 more
openaire +4 more sources
Complement C3 inhibition reduces complement activation in clinical platelet concentrates but does not counteract platelet storage lesions [PDF]
Platelet storage is associated with storage lesions, including platelet morphological changes and a gradual functional loss. We investigated the impact of complement C3 inhibition on complement activation and platelet storage lesions in clinical platelet
Linnea I. Andersson +7 more
doaj +2 more sources
Evaluating platelet concentrates by platelet indices, thromboelastography, and flow cytometry [PDF]
INTRODUCTION: Platelet transfusion has been therapeutically used in patients with thrombocytopenia and platelet function defects over the years. The use of advanced techniques may add value in assessing the quality of platelet products.
Tapasyapreeti Mukhopadhyay +6 more
doaj +2 more sources
DAMPS and complement activation in platelet concentrates that induce adverse reactions in patients [PDF]
Background: Patients with severe thrombocytopenia due to bone marrow failure and after chemotherapy are still treated with platelet transfusions. Platelet concentrates (PC) are associated with a high incidence of adverse reactions (AR).
Hind Hamzeh‐Cognasse +13 more
core +1 more source
Platelet concentrates in platelet additive solutions generate less complement activation products during storage than platelets stored in plasma. [PDF]
BACKGROUND Platelet transfusions can be associated with adverse reactions, such as febrile non-haemolytic transfusion reaction (FNHTR). It has been suggested that damage-associated molecular patterns (DAMP) and complement play a role in FNHTR.
Bulder, Ingrid +16 more
core +1 more source
Evaluation of platelet aggregation in platelet concentrates: storage implications [PDF]
The use of hemo-derivatives is nowadays a fundamentally important therapeutic modality in the exercise of medicine. Among the various hemo-components employed, we have the platelet concentrate (PC), indicated in cases of hemorrhagic disturbances.
Neiva Teresinha J.C. +6 more
doaj +1 more source
Platelet activation and aggregation: Clinical and experimental studies [PDF]
Background: Dual antiplatelet therapy with acetylsalicylic acid (ASA) and the adenosine diphosphate (ADP)-receptor antagonist ticagrelor increases the risk of bleeding complications during cardiac surgery.
Singh, Sukhi
core +3 more sources

