Results 71 to 80 of about 50,756 (301)

Using Platelet-Rich Plasma to Reverse the Effects of Tendinopathy and Prevent Tendon Re-rupture after Surgery in Athletes: The Search for a Standardized Protocol [PDF]

, 2016
30-50% of all lesions amateur and professional sports players will experience during activity are related to the tendon. Moreover, the incidence of tendinopathy, a precursor to tendon rupture, is much higher in both of these groups due to excessive ...
Patel, Shiv
core   +1 more source

Soft tissue regeneration using leukocyte-platelet rich fibrin after exeresis of hyperplastic gingival lesions: Two case reports [PDF]

, 2015
Introduction The Leukocyte-PRF (Leukocyte-Platelet Rich Fibrin) belongs to a second generation of platelet concentrates which doesn’t need a biochemical blood manipulation.
Abbate, D., Dell'Angelo, B., DI LAURO, ALESSANDRO ESPEDITO, Iannaccone, G. A., SAMMARTINO, GILBERTO, Scotto, F.   +5 more
core   +1 more source

Angiogenic Properties of ‘Leukocyte- and Platelet-Rich Fibrin’ [PDF]

Scientific Reports, 2018
AbstractLeukocyte- and Platelet-Rich Fibrin (L-PRF) is an autologous platelet concentrate, consisting of a fibrin matrix enriched with platelets, leukocytes and a plethora of cytokines and growth factors. Since L-PRF is produced bedside from whole blood without the use of an anti-coagulant, it is becoming a popular adjuvant in regenerative medicine ...
Ratajczak, Jessica, Vangansewinkel, Tim, Gervois, Pascal, Merckx, Greet, Hilkens, Petra, Quirynen, Marc, Lambrichts, Ivo, Bronckaers, Annelies   +7 more
openaire   +3 more sources

Platelet-rich plasma and platelet-rich fibrin in oral surgery: A narrative review

Dental and Medical Problems, 2023
Platelet-rich plasma (PRP) and platelet-rich fibrin (PRF) are biological products derived from the plasma fraction of autologous blood that have a platelet concentration above that of the original blood. Cytokines and growth factors are present in platelet-based preparations, and their application has gained great attention in dentistry.
Dominika Egierska, Michał Perszke, Marta Mazur, Irena Duś-Ilnicka   +3 more
openaire   +2 more sources

Activated Platelet–Released Heat Shock Protein 90α Triggers Autophagy‐Dependent Neutrophil Extracellular Trap Formation and Amplifies Sepsis

Advanced Science, EarlyView.
HSP90α is significantly upregulated in platelets from sepsis patients, with its origin from megakaryocyte‐derived trafficking. Furthermore, activated platelets secrete HSP90α into the extracellular space in both free and exosome‐associated forms. Finally, extracellular HSP90α directly engages TLR4 on neutrophils to induce autophagy, leading to NET ...
Chengbo Wang, Maodong Leng, Chenchen Sun, Jingyu Cao, Linfei Li, Yangyang Jia, Yongshuai Han, Yuchun Liu, Yaodong Zhang, Chenglong Zhang, Yingli Men, Ningyuan Liu, Yibing Cheng, Yixia Zhang, Ya Li, Zhenlong Li, Lidan Cui, Xiangzhan Zhu   +17 more
wiley   +1 more source

Platelet Rich Fibrin in Dentistry

Journal of Advance Research in Medical & Health Science (ISSN: 2208-2425), 2018
 Platelet rich fibrin (PRF) is a fibrin matrix in which platelet cytokines, growth factors and cells are trapped and may be released after a certain time and that can serve as a resorbable membrane. In the present review article, the evolution, preparation of PRF has been described.
Satwik Sham Gundawar, Sudhindra Baliga, Nilima Thosar, Nilesh Rathi   +3 more
openaire   +2 more sources

Bench‐to‐Bedside Translation of Self‐Healing Colloidal Hydrogels as Next Generation Design of Flowable Hemostatic Matrix: From Preclinical Evaluation to Human Clinical Trials

Advanced Science, EarlyView.
ABSTRACT Self‐healing materials represent a paradigm shift in designing functional biomedical devices for drug delivery, tissue regeneration, and 3D bioprinting. However, their clinical translation remains limited by challenges such as insufficient mechanical strength, potential cytotoxicity from chemical modifications, and complex activation ...
Ganjun Feng, Kaiwen Chen, Qiwei Ying, Shuya Wang, Xin Li, Guanlin Li, Yantao Zhao, Binghua Ma, Huanan Wang, Dawei Li, Lijun Zhang, Jian Zhang, Yu Zhao, Changle Ren, Baodong Chen, Yueming Song   +15 more
wiley   +1 more source

A multiscale hybrid mathematical model of epidermal-dermal interactions during skin wound healing. [PDF]

, 2019
Following injury, skin activates a complex wound healing programme. While cellular and signalling mechanisms of wound repair have been extensively studied, the principles of epidermal-dermal interactions and their effects on wound healing outcomes are ...
Chen, Weitao, Du, Huijing, Figueroa, Seth, Guerrero-Juarez, Christian F, Nie, Qing, Plikus, Maksim V, Qiu, Yuchi, Wang, Yangyang   +7 more
core   +1 more source

A Photothermal‐Responsive PRP‐Loaded Hydrogel Engineered With Composite Nanobottle for Controllable Delivery of Growth Factors and Multifunctional Therapy of Diabetic Wounds

Advanced Science, EarlyView.
A photothermal‐responsive engineered platelet‐rich plasma hydrogel (CNB‐ePRP) incorporated with thrombin‐functionalized composite nanobottle was developed, which enables in situ PRP activation, on‐demand growth factor release, multifunctionality, and personalized antimicrobial loading for treatment of diabetic wounds. The CNB‐ePRP hydrogel demonstrated
Wen‐Qiang Qu, Hui‐Yun Gu, Si‐Min Zeng, Chang‐Jiang Liu, Xiao Yan, Ting Pan, Chao Jian, Xian‐Zheng Zhang, Ai‐Xi Yu   +8 more
wiley   +1 more source

Influence of Injectable Platelet-Rich Fibrin on ex vivo Leak Pressure of Canine Enterotomy [PDF]

Iranian Journal of Veterinary Surgery
Injectable platelet rich fibrin, the latest innovation among platelet concentrates is obtained by centrifugation of whole blood without any anticoagulants. The initially liquid product is later converted into gel form due to conversion of fibrinogen into
Ali Heydari Azar Heris, Davoud Kazemi
doaj   +1 more source