Results 141 to 150 of about 2,958,013 (281)

The Effect of the MTHFR C677T Genotype Polymorphism on the Efficacy of Folic Acid Treatment for Hyperhomocysteinemia and Cardiovascular Endothelial Function

open access: yesChronic Diseases and Translational Medicine, EarlyView.
Flowchart of patient enrollment. ABSTRACT Background Cardiovascular disease remains a major public health burden. This study aimed to investigate the effect of the methylenetetrahydrofolate reductase (MTHFR) C677T genotype on folic acid treatment response and cardiovascular endothelial function in patients with hyperhomocysteinemia (HHcy).
Xiaohui Dou   +8 more
wiley   +1 more source

Increased Insulin Action, Glucose Metabolism and Muscle Function in Supervillin‐Knockout and Supervillin‐Mutant Mice

open access: yesCytoskeleton, EarlyView.
ABSTRACT We here describe mouse models with complementary homozygous Svil mutations. In skeletal muscle, Svil‐Mut mice express the Svil‐encoded N‐terminus fused to the βgal‐neo gene‐trap tag and lack the highly conserved archvillin C‐terminus; Svil‐KO mice lack expression of all known Svil‐encoded proteins; and Svil‐LoxP mice contain loxP sites for ...
Tara C. Smith   +9 more
wiley   +1 more source

Platelet-rich plasma (PRP) treatment of noninsertional Achilles tendinopathy in a two case series: no significant difference in effect between leukocyte-rich and leukocyte-poor PRP

open access: yes, 2019
Klaus Hanisch,1 Niels Wedderkopp1,2 1Orthopedic Department, Hospital of Southwestern Jutland, Esbjerg, Denmark; 2Department of Regional Health Research, University of Southern Denmark, Odense, Denmark Background: There is a theoretical basis for the ...
Hanisch K, Wedderkopp N
core  

Virtual Twin Approach Using Physiologically Based Pharmacokinetic Modeling to Support Precision Dosing of Valproic Acid in Geriatric Patients

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Personalized dosing is particularly important for drugs with narrow therapeutic indices in geriatric patients, who exhibit substantial physiological variability and limited pharmacokinetic (PK) evidence to guide individualized dose selection. Valproic acid (VPA) is an effective treatment option for bipolar disorder in older adults, yet dosing largely ...
Yoo Jin Jang   +2 more
wiley   +1 more source

Membrane lipid metabolism as a regulatory frontier in neural crest biology: Roles for sphingolipids, cholesterol, and lipid rafts

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Neural crest cells are multipotent, migratory stem‐like cells essential for vertebrate development that contribute broadly to many tissues including the craniofacial skeleton, peripheral nervous system, and pigment‐producing cells. Their development progresses through phases of induction, specification, delamination, migration, and ...
Allison E. Mancini   +2 more
wiley   +1 more source

Photothermal-Activated Platelet-Rich Plasma Versus Conventional Platelet-Rich Plasma for Melasma: A Split-Face, Double-Blind Randomized Controlled Trial. [PDF]

open access: yesPhotodermatol Photoimmunol Photomed
Siriphanit R   +5 more
europepmc   +1 more source

Application of PRP (Platelet-Rich Plasma) in Tissue Engineering

open access: yes, 2006
The goal of periodontal therapy is the protection and maintance of patient's natural dentition over his or her lifetime for optimalaesthetic appearance and function.
L. Izakovičová Hollá   +4 more
core  

Electrolytic (C2CNT) Carbon Nanotubes Made From CO2 as an Inexpensive Carbon Sink and High‐Capacity Li‐Ion Battery Graphite Replacement

open access: yesEcoEnergy, EarlyView.
Carbon‐negative carbon nanotubes produced by molten CO2 electrolysis offer a low‐cost, high‐performance alternative to graphite in Li‐ion battery anodes. Replacing conventional carbon materials with electrolytic CNTs can improve battery capacity and charging performance while reducing costs and contributing to carbon mitigation.
Gad Licht, Stuart Licht
wiley   +1 more source

Tellurium Electrochemistry: From Mechanistic Analysis in Diverse Electrolytic Media to Advanced Energy Storage Applications

open access: yesENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
As a metalloid with broad prospects in advanced applications, Te has not been fully clarified in terms of its intricate electrochemical behaviors across varied systems. This review systematically integrates fundamental electrochemical mechanisms, reaction kinetics identifications, and device application insights, establishing a comprehensive framework ...
Meng Zhang   +6 more
wiley   +1 more source

Home - About - Disclaimer - Privacy