Results 171 to 180 of about 140,688 (406)

A Subset of Pro‐inflammatory CXCL10+ LILRB2+ Macrophages Derives From Recipient Monocytes and Drives Renal Allograft Rejection

Advanced Science, EarlyView.
This study uncovers a recipient‐derived monocyte‐to‐macrophage trajectory that drives inflammation during kidney transplant rejection. Using over 150 000 single‐cell profiles and more than 850 biopsies, the authors identify CXCL10+ macrophages as key predictors of graft loss.
Alexis Varin, Jovanne Palvair, Lennie Messager, Jamal Bamoulid, Jasper Callemeyn, Mélanie Chaintreuil, Ludivine Dal Zuffo, Didier Ducloux, Imane Farhat, Mathieu Legendre, Laurent Martin, Florian Renosi, Xavier Roussel, Thibaut Vaulet, Maarten Naesens, Claire Tinel, Baptiste Lamarthée   +16 more
wiley   +1 more source

Engineering Immune Cell to Counteract Aging and Aging‐Associated Diseases

Advanced Science, EarlyView.
This review highlights a paradigm shift in which advanced immune cell therapies, initially developed for cancer, are now being harnessed to combat aging. By engineering immune cells to selectively clear senescent cells and remodel pro‐inflammatory tissue microenvironments, these strategies offer a novel and powerful approach to delay age‐related ...
Jianhua Guo, Lanjie Lei, Ying Jin, Lan Su, Shumao Cui, Liyun Shi   +5 more
wiley   +1 more source

Prognostic value of neutrophil‐to‐lymphocyte ratio and platelet‐to‐lymphocyte ratio for breast cancer patients: An updated meta‐analysis of 17079 individuals

Cancer Medicine, 2019
This study aimed to evaluate the prognostic effect of neutrophil‐to‐lymphocyte ratio (NLR) and platelet‐to‐lymphocyte ratio (PLR) for patients with breast cancer (BC).
Wanying Guo, Xin Lu, Qipeng Liu, Ting Zhang, Peng Li, Weiqiang Qiao, Miao Deng   +6 more
semanticscholar   +1 more source

Assessment of neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio, and mean platelet volume in patients with diabetic retinopathy

Journal of Clinical Ophthalmology and Research
Objective: The objective of this study was to assess the role of inflammation in the pathogenesis of diabetic retinopathy (DR) using the neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), and mean platelet volume (MPV) and to ...
Trisha Ghosh, Sanjay Kumar Daulat Thakur, Premangshu Ghosh, Trina Sengupta   +3 more
doaj   +1 more source

Pearl‐Like Bioinspired Coating Enables Regulation of Mg Degradation for Osteoporotic Bone Repair

Advanced Science, EarlyView.
In this study, inspired by pearl architecture, we developed a layered Ca–P “brick” and Fn‐mimetic peptide “mortar” coating on Mg alloys. The Ca–P layer moderates corrosion and offers mineral cues, while the peptide enhances adhesion and regulates immune‐vascular responses.
Siming Zhang, Tao Zhang, Yuan Chen, Nikolaos Kourkoumelis, Mo Chen, Jiale Dong, Zhenyu Li, Yanling Zhou, Ning Li, Chen Zhu, Xifu Shang, Jiaxiang Bai, Xianzuo Zhang   +12 more
wiley   +1 more source

Platelet-to-Lymphocyte Ratio and Neutrophil-to-Lymphocyte Ratio in Patients With Locally Advanced Gastric Cancers

, 2022
Ahmet KARAYİĞİT, Dursun Burak ÖZDEMİR, Hayrettin Dizen, Murat Ulaş   +3 more
openalex   +1 more source

To evaluate role of Neutrophil to lymphocyte ratio and Platelet to Lymphocyte ratio as diagnostic marker in children with acute exacerbation of bronchial asthma. [PDF]

, 2023
V. Parihar, Doug Thake, Ghanshyam Singh Sengar, Dr.Mukesh Beniwal   +3 more
openalex   +1 more source

Metformin‐Based Covalent Organic Frameworks With Excellent Biosafety and High Efficiency against Pathogenic Microorganisms

Advanced Science, EarlyView.
This work presents the first metformin‐based COFs featuring built‐in biosafety and a unique triple‐synergy mechanism. This scalable platform achieves broad‐spectrum eradication of bacteria and viruses, enabling reusable protective membranes with exceptional biocompatibility for advanced biomedical applications and personal protection.
Jia‐Yi Liu, Hong Jiang, Lei Ma, Jin‐Yi Yu, Ming‐Yi Yang, Hao‐Ru Wang, Jun‐Yuang Tang, Shengfeng Huang, Wei Yi, Meng Lu, Ya‐Qian Lan, Xu‐Jia Hong   +11 more
wiley   +1 more source

The platelet-to-lymphocyte ratio as a significant prognostic factor to predict survival outcomes in patients with synchronous metastatic renal cell carcinoma

, 2020
Hyeong Dong Yuk, Minyong Kang, Eu Chang Hwang, Jae Young Park, Chang Wook Jeong, Cheryn Song, Seong Il Seo, Seok‐Soo Byun, Cheol Kwak, Sung‐Hoo Hong, Jinsoo Chung, Hakmin Lee, the Korean Renal Cancer Study (KRoCS) Group   +12 more
openalex   +1 more source

Defect‐Rich 2D Layered Double Hydroxides Enhance Sonodynamic Antibacterial Therapy

Advanced Science, EarlyView.
This study develops defect‐rich ultrathin ZnCuW‐LDH nanosheets (DR‐ZnCuW‐LDH) via acid etching. DR‐ZnCuW‐LDH exhibits fourfold enhanced US‐triggered ROS production due to oxygen defects and electronic modulation, demonstrating potent antibacterial efficacy in vitro/vivo.
Qian Liu, Yu Yang, Rui Zhao, Linwei Huang, Xingyu Qi, Min Wu, Jianliang Shen   +6 more
wiley   +1 more source