Results 11 to 20 of about 1,292,372 (416)
Japanese Journal of Thrombosis and Hemostasis, 1991 血 小 板 活 性 化 因 子(platelet-activating factor, PAF)は,現 在 の と こ ろ唯 一 非 常 に 強 力 な 生 理 活 性 を持 つ リン脂 質 で あ り,そ の 本 体 は ア ル キ ル エ ー テ ル 型 コ リ ン リ ン脂 質(1-0-alkyl2-acetyl-sn-glycero-3-phosphocholine, alkylacetyl-GPCho)で あ る(Fig.1).そ の 特 異 的 な構 造 の 一 つ で あ る ア ル キ ...
Jun-ichi Kambayashi, Tomio Kawasaki
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Hearts, 2021 The purpose of this literature review is to gain an overview of the role of platelet-activating factor (PAF) within each of the body systems and how it contributes to normal and pathophysiological states.
Nilank Shah, Karan Kumar, Nikeith Shah
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UVB-Induced Microvesicle Particle Release and Its Effects on the Cutaneous Microenvironment
Frontiers in Immunology, 2022 Ultraviolet B radiation (UVB) has profound effects on human skin that results in a broad spectrum of immunological local and systemic responses and is the major cause of skin carcinogenesis.
Timothy C. Frommeyer +10 more
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Cardiogenetics, 2022 Hypertension and atherosclerosis are debilitating diseases that affect millions each year. Long-term consequences include but are not limited to stroke, myocardial infarction, and kidney failure.
Nilank Shah +7 more
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Platelet-activating factor receptor in GtoPdb v.2023.1 [PDF]
, 2023 Platelet-activating factor (PAF, 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine) is an ether phospholipid mediator associated with platelet coagulation, but also subserves inflammatory roles.
Hills, Rebecca +8 more
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Molecular Docking, Drug likeness Studies and ADMET prediction of Flavonoids as Platelet-Activating Factor (PAF) Receptor Binding [PDF]
Chemical Review and Letters, 2021 Studies and scientific research indicate that the platelet-activating factor (PAF) is a major pro-inflammatory mediator in the initiation and development of cancer.
Mohammed BOUACHRINE +6 more
doaj +1 more source
Mechanobiology of shear-induced platelet aggregation leading to occlusive arterial thrombosis: a multiscale in silico analysis [PDF]
, 2021 Occlusive thrombosis in arteries causes heart attacks and strokes. The rapid growth of thrombus at elevated shear rates (~10,000 1/s) relies on shear-induced platelet aggregation (SIPA) thought to come about from the entanglement of von Willebrand factor (VWF) molecules.
arxiv +1 more source
Factor V activity of platelets: evidence for an activated factor V molecule and for a platelet activator [PDF]
Blood, 1977 Abstract This study was prompted by the observation that fresh platelet suspensions--prepared by gel filtration or albumin density gradient centrifugation--possessed only minimal factor V activity, whereas frozen-and-thawed platelet suspensions possessed striking factor V activity.
Samuel I. Rapaport +5 more
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Clinical and Translational Allergy, 2019 Background Platelet activating factor (PAF) is an endogenous, active phospholipid released from inflammatory cells, platelets, and endothelial cells, and is involved in the regulation of immune responses. Degradation of PAF by PAF acetylhydrolase (PAF-AH)
Bastsetseg Ulambayar +5 more
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