Results 21 to 30 of about 200,980 (357)

Structural identification of oxidized acyl-phosphatidylcholines that induce platelet activation [PDF]

, 2005
Oxidation of low-density lipoprotein (LDL) generates proinflammatory and prothrombotic mediators that may play a crucial role in cardiovascular and inflammatory diseases.
Berliner JA, Bittman R, Casals-Stenzal J, Esterbauer H, Fernandez-Ortiz A, Frey B, Goetzl EJ, Holvoet P, Itabe H, Kamido H, Kamido H, Kern H, Kinsella BT, Kitagawa S, O'Flaherty JT, O'Flaherty JT, Rasmussen UB, Sevanian A, Subbanagounder G, Tanaka T, Trip MD, Volf I, Watson AD, Weidtmann A   +23 more
core   +1 more source

Plasma PAF-acetylhydrolase in patients with coronary artery disease: results of a cross-sectional analysis

Journal of Lipid Research, 2003
Inflammation underlies both onset and perpetuation of atherosclerosis. Plasma lipoproteins transport the platelet-activating factor-acetylhydrolase (PAF-AH) with potentially anti-inflammatory activities.
Stefan Blankenberg, Dominique Stengel, Hans J. Rupprecht, Christoph Bickel, Ju¨rgen Meyer, François Cambien, Laurence Tiret, Ewa Ninio   +7 more
doaj   +1 more source

Pharmacologic modulation of experimental postischemic hepatic function [PDF]

, 1989
The present study, evaluated and compared the effects of SRI 63-441, a potent platelet activating factor antagonist, superoxide dismutase (SOD), an oxygen free radical scavenger, and ibuprofen, a cyclooxygenase inhibitor on hepatic function after 90 ...
Makowka, L, Mazzaferro, V, Ontell, SJ, Ove, P, Starzl, TE, Trager, J   +5 more
core   +2 more sources

Opposing Effects of Platelet-Activating Factor and Lyso-Platelet-Activating Factor on Neutrophil and Platelet Activation

Molecular Pharmacology, 2009
Platelet-activating factor (PAF) is a potent, bioactive phospholipid that acts on multiple cells and tissues through its G protein-coupled receptor (GPCR). PAF is not stored but is rapidly generated via enzymatic acetylation of the precursor 1-O-hexadecyl-2-hydroxy-sn-glycero-3-phosphocholine (lysoPAF). The bioactivity of PAF is effectively and tightly
Emily J, Welch, Ram P, Naikawadi, Zhenyu, Li, Phoebe, Lin, Satoshi, Ishii, Takao, Shimizu, Chinnaswamy, Tiruppathi, Xiaoping, Du, Papasani V, Subbaiah, Richard D, Ye   +9 more
openaire   +3 more sources

Lipopolysaccharide induces nitric oxide synthase expression and platelet-activating factor increases nitric oxide production in human fetal membranes in culture

Reproductive Biology and Endocrinology, 2004
Background Platelet-activating factor and nitric oxide may be involved in the initiation of human labour as inflammatory mediators. The aim of this study was to test whether platelet-activating factor and lipopolysaccharide were able to induce nitric ...
Seyffarth Gunter, Nelson Paul N, Dunmore Simon J, Rodrigo Nalinda, Murphy Damian J, Carson Ray J   +5 more
doaj   +1 more source

Modification of biological parameters after treatment with recombinant factor VIIa in a patient with thrombocytopathy due to storage pool disease [PDF]

, 2005
Patients with thrombocytopathy due to storage pool disease mostly suffer from mild bleeding diathesis. However surgical interventions can lead to excess bleeding.
Almeida, Bick, Hoffman, Kristensen, Lisman, Lisman, Lisman, Peters, Poon, Van Tilburg, White   +10 more
core   +3 more sources

Novel molecular analogues of phosphatidylcholines in a lipid extract from bovine brain: 1-long-chain acyl-2-short-chain acyl-sn-glycero-3-phosphocholines.

Journal of Lipid Research, 1989
A vasodepressor phospholipid fraction named Depressor-IA from a bovine brain lipid extract was analyzed by capillary gas-liquid chromatography-mass spectrometry as tert-butyldimethylsilyl derivatives after hydrolysis with phospholipase C.
A Tokumura, K Takauchi, T Asai, K Kamiyasu, T Ogawa, H Tsukatani   +5 more
doaj   +1 more source

Hemodialysis membrane-related neutrophil dysfunctions and pentoxifylline - a pilot study [PDF]

, 1990
Hemodialysis treatment is associated with activation of neutrophil granulocytes. Pentoxifylline has been shown to inhibit neutrophil activation in vitro and in vivo.
Hoffmann, H., Jochum, Marianne, Schiffl, H., Spannagl, Michael   +3 more
core   +1 more source

Production of platelet-activating factor by washed rabbit platelets

Journal of Lipid Research, 1985
Production of platelet-activating factor by washed rabbit platelets under stimulation with the ionophore A23187 was investigated utilizing two groups of platelet preparations.
M Oda, K Satouchi, K Yasunaga, K Saito
doaj   +1 more source

Platelets and galectins [PDF]

, 2014
A major function of platelets is keeping the vascular system intact. Platelet activation at sites of vascular injury leads to the formation of a hemostatic plug.
Schattner, Mirta Ana
core   +1 more source