Results 371 to 380 of about 4,080,787 (408)
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Desensitization of human platelets by platelet activating factor
Biochemical and Biophysical Research Communications, 1985Human platelets are less responsive to PAF at 37 degrees than at 25 degrees. They can be desensitized to the effects of PAF by pre-exposure to small concentrations. In both cases desensitization appears to be accompanied by a decreased affinity of the high affinity site for PAF rather than loss of binding sites.
Carolyn M. Chesney +2 more
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The role of platelet-activating factor in platelet aggregation
Nature, 1979PLATELET aggregation is mediated by at least three distinct mechanisms1,2. The first involves the release of ADP and is inhibited by its conversion to ATP by the combination of creatine phosphate and creatine phosphokinase (CP/CPK). The second is mediated by metabolites of arachidonic acid, particularly thromboxane A2 (TXA2), and is blocked by aspirin ...
J P Le Couedic +4 more
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Platelet activation in unstable coronary disease.
New England Journal of Medicine, 1986Pathological and clinical studies have suggested that platelets have a role in the pathogenesis of unstable angina and myocardial infarction. However, the relation of platelet activation to episodic ischemia in patients with unstable angina is unknown ...
D. Fitzgerald +3 more
semanticscholar +1 more source
Platelet Microparticles: A Carrier of Platelet-Activating Factor?
Biochemical and Biophysical Research Communications, 1996Platelet-activating factor (PAF) has been considered to be released in a soluble form from activated platelets. Also a considerable number of microparticles were released from stimulated platelets. To evaluate the possibility that microparticles contain PAF, the amount of PAF in whole activated platelets, microparticles and the suspending medium was ...
Hideo Ariyoshi +4 more
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Platelet-activating factor and asthma
Journal of Allergy and Clinical Immunology, 1988anaphylaxis. And if you research into the 1920s) there a very useful treatment in blocking both thrombocyare articles, particularly in the German literature, that topenia and some of the features of anaphylaxis. The report thrombocytopenia as being a feature of clinical first article (1924) stated that heparin totally prevents asthma.
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Heparin and platelet activation
Thrombosis Research, 2012Dimitri P. Mikhailidis, I. Anita Jagroop
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Platelet Activation in Migraine
Thrombosis and Haemostasis, 1983C. Manotti +2 more
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