Results 331 to 340 of about 1,089,521 (397)

Platelet aggregation by platelet-clumping substance

Thrombosis Research, 1974
Abstract The platelet-clumping substance isolated from rabbit plasma by the authors aggregated washed rabbit platelets, while ADP did not. The presence of AMP or adenosine did not inhibit the appearance of platelet aggregation induced by the clumping substance.
H, Yamazaki, T, Sano, T, Shimamoto, T, Shimamoto   +3 more
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Platelet aggregation and platelet-inhibiting drugs

Neurochemical Pathology, 1987
Platelet function may cause a progression of central gray matter damage after cerebrospinal hemorrhage or trauma because of the thrombotic occlusion of injured vessels or a vasospasm induced by extravasated blood. It has therefore been suggested that antiplatelet drugs could limit the extent of the neurological lesions produced by a spinal trauma.
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Mechanisms of platelet aggregation

Current Opinion in Hematology, 2001
Platelet aggregation is initiated by receptor activation coupled to intracellular signaling leading to activation of integrin alphaIIbbeta3. Recent advances in the study of platelet receptors for collagen, von Willebrand factor, thrombin, and adenosine diphosphate are providing new insights into the mechanisms of platelet aggregation.
B. Savage, M. Cattaneo, Z. Ruggeri
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Platelet aggregation in myotonia

Journal of the Neurological Sciences, 1985
Platelet function tests were carried out on 21 patients with myotonic dystrophy (MyD) and 7 patients with myotonia congenita (MC) together with 22 healthy subjects. Compared to the controls, the MyD and MC patients showed significantly greater sensitivity to the calcium ionophore A23187 but not to adenosine diphosphate, collagen, ristocetin or ...
A H, Schapira, R A, Hutton
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Platelet aggregation and glaucoma

Documenta Ophthalmologica, 1985
In this study platelet aggregation was determined in 79 patients with primary open angle glaucoma (POAG) and 81 patients suspected of having glaucoma (ocular hypertension). There is a positive association between high age and the presence of vascular diseases (p less than 0.01). An age dependent association between spontaneous platelet aggregation (SPA)
P F, Hoyng, E L, Greve, K, Frederikse, C, Geijssen, H, Oosting   +4 more
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Platelet aggregation in Hyperapobetalipoproteinemia

American Journal of Hematology, 1991
AbstractHyperapobetalipoproteinemia (HyperapoB) is a lipid disorder characterized by premature coronary disease, although the mechanisms have not been elucidated. Because abnormalities in platelet function may represent an enhanced susceptibility to coronary thrombosis, the aggregability of platelets was examined in hyperapoB subjects.
M, Miller, W, Bell, S, Plano, J, Connors, S, Kennedy, P, Kwiterovich   +5 more
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Platelet aggregability in migraine

Neurology, 1977
Employing optical density methods, platelet aggregation in response to 1.275, 1.7, and 3.4 micrometer adenosine diphosphate was tested in 46 patients with migraine and 46 controls matched by age, sex, and race. The migraine patients demonstrated platelet hyperaggregability when compared with controls, as manifested by a lower threshold for the platelet-
J R, Couch, R S, Hassanein
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PROSTAGLANDINS AND PLATELET AGGREGATION

Acta Medica Scandinavica, 1981
ABSTRACTProstaglandins may induce or inhibit platelet aggregation and constrict or dilate blood vessels. Recent interest has focussed on prostaglandins which are derivatives of arachidonic acid including prostaglandin endoperoxides, thromboxane A2, prostaglandin E2, prostaglandin D2and prostacyclin.
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Prostaglandins in Platelet Aggregation

Scandinavian Journal of Clinical and Laboratory Investigation, 1969
The inhibitory effect of different prostaglandins on ADP-induced platelet aggregation has been studied using a technique similar to that of Born and O'Brien. PGE 1 has a high inhibiting capacity while PGE 2 shows about one-fifth of that. The activity of the other prostaglandins investigated (PGE 1–217, PGF 2 α, PGF 1 β and PGF 1 α) is much lower.
E, Irion, M, Blombäck
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Purinoceptors and platelet aggregation

Journal of Autonomic Pharmacology, 1996
1. Adenosine 5'-diphosphate (ADP) is a physiologically important mediator, being released from damaged cells and from aggregating platelets. It acts on platelets to cause aggregation via a purinoceptor ('P2T-purinoceptor') at which adenosine 5'-triphosphate (ATP) is a competitive antagonist; however, the way in which it does so is not fully understood.
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