Results 201 to 210 of about 2,173,038 (398)

Microfluidic Electrochemical Biosensor for the Detection of Platelet Factor 4 Antibody‐Mediated Thrombotic Disorders

Advanced Science, EarlyView.
A microfluidic electrochemical biosensor enables sensitive and specific detection of antibodies associated with vaccine‐induced immune thrombotic thrombocytopenia (VITT) and heparin‐induced thrombocytopenia (HIT). The platform uses two antigen targets— platelet factor 4 (PF4) and cross‐linked‐PF4 (c‐PF4)—and microliter volumes of patient sera to ...
Diana F. Cedillo‐Alcantar, Adam Kanack, Seonhwa Lee, Alan M. Gonzalez‐Suarez, Kihak Gwon, Emily Mauch, Thi Thanh‐Qui Nguyen, Anand Padmanabhan, Alexander Revzin   +8 more
wiley   +1 more source

Preliminary analysis of CD41 monoclonal antibody failed to establish a mouse model of chronic immune thrombocytopenia

Huli yanjiu
ObjectiveCD41 monoclonal antibody（MWReg30） was injected into Balb/c mice at different times and doses to investigate whether this method can construct a stable model of chronic Immune thrombocytopenia（ITP）.After the modeling，the extract of Codonopsis ...
ZHANG Jun, ZHU Ruifang, LYU Yaru, LI Ruolan, ZHANG Shuwen, LI Na, SONG Kai, ZENG Jinghui, HAN Shifan   +8 more
doaj  

CD8+ T cells mediate antibody-independent platelet clearance in mice [PDF]

, 2016
Connie M. Arthur, Seema R. Patel, H. Cliff Sullivan, Annie M. Winkler, C Tormey, Jeanne E. Hendrickson, Sean R. Stowell   +6 more
openalex   +1 more source

Combined Photothermal and mTOR‐Targeted Therapy Overcomes Immune Evasion and Enhances Checkpoint Blockade Efficacy in Metastatic Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
This study reveals that photothermal therapy, while inducing immunogenic cell death in triple‐negative breast cancer, paradoxically activates the oncogenic mTOR pathway to drive immune evasion. To counter this, a smart nanocomposite is engineered to co‐deliver localized hyperthermia and mTOR inhibition.
Yujie Zhao, Jing Yu, Xin Wang, Xu Liu, Fengli Zuo, Tianyue Xu, Leyi Tang, Ling Xiong, Li Li, Huifang Li, Xiaoting Chen, Guang Yang, Jing Jing, Xiaowei Liu   +13 more
wiley   +1 more source

Analysis of Platelet Membrane Glycoproteins and The Specific Antibodies in MYH9-Related Diseases

International Journal of General Medicine
Lin Wang,1,2,* Ke Cao,3,* Shiyang Chen,3 Xiaoying Fu,3 Yunsheng Chen,3 Xiaojuan Luo1,3 1Shantou University School of Medicine, Shantou, Guangdong, 515000, People’s Republic of China; 2Department of Clinical Laboratory, The Seventh ...
Wang L, Cao K, Chen S, Fu X, Chen Y, Luo X   +5 more
doaj  

Targeting macrophages prevents alloantibody-mediated platelet clearance in a murine model of transfusion refractoriness. [PDF]

Blood Adv
Rojas-Jiménez G, Angénieux C, Proamer F, Eckly A, Maître B.   +4 more
europepmc   +1 more source

Platelet Factor 4-Heparin Antibody as a Predictor of Cardiovascular and Thrombotic Events in Hemodialysis [PDF]

Mohamed Kamal Dewedar, Mahmoud Abd, El-Aziz Kora, Ahmed Tawfeek, Mahmoud Emara, Heba El-Sayed, Kasem   +6 more
openalex   +1 more source

The effect of peptides and monoclonal antibodies that bind to platelet glycoprotein IIb-IIIa complex on the development of clot tension [PDF]

, 1989
I Cohen, Dan L. Burk, JG White
openalex   +1 more source

Increased Blood Flow and Tendon Swelling Precedes Vascular Expansion and Tissue Matrix Changes In Early Human Tendinopathy: A Potential Window for Superior Treatment Response

Advanced Science, EarlyView.
Human participants with early‐ or chronic‐stage tendinopathy and healthy controls are investigated using ultrasound Doppler, 3T and 7T MRI, and tendon biopsies. Tendon swelling and hyperperfusion are evident early, while vascular growth and extracellular matrix changes are most pronounced in chronic tendinopathy. Early intervention may provide superior
Max F. R. Merkel, Nikolaj M. Malmgaard‐Clausen, Marius Lendal, Hartwig R. Siebner, René B. Svensson, Stephanie G. Dakin, Marcus Krüger, Luisa Schmidt, Jakob Agergaard, Ching‐Yan Chloé Yeung, S. Peter Magnusson, Michael Kjaer   +11 more
wiley   +1 more source

Antigenic assessment for the β2-glycoprotein I/Platelet factor 4 complex in thrombotic patients with antiphospholipid syndrome. [PDF]

Front Immunol
Villani F, Capozzi A, Ucci FM, Truglia S, De Michele M, Mancuso S, Rapino L, Tripodi G, Manganelli V, Riitano G, Misasi R, Sorice M, Sili Scavalli A, Conti F, Alessandri C.   +14 more
europepmc   +1 more source