Results 321 to 330 of about 2,173,038 (398)
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Platelet Antibodies

Clinics in Laboratory Medicine, 1996
The proper diagnosis of patients with immune-mediated thrombocytopenias can be accomplished by using the advances made in the field of platelet serology. These techniques range from solid phase red cell adherence to sequencing platelet antigen amino acids by polymerase chain reaction.
openaire   +2 more sources

Platelet Antibodies in Thrombocytopenic Patients

British Journal of Haematology, 1977
Platelet antibodies either bound to the surface of platelets or free in the serum were sought in patients who had low platelet counts for a variety of reasons. They were detected by finding excess IgG on the surface of washed platelets either directly or after incubation of the serum with normal platelets.
U M, Hegde   +2 more
openaire   +2 more sources

Comparison of microscopic and flow cytometric detection of platelet antibody in dogs suspected of having immune-mediated thrombocytopenia.

American Journal of Veterinary Research, 1994
A flow cytometric platelet immunofluorescence assay (FC-PIFA) was compared with a previously developed microscopic platelet immunofluorescence assay (MI-PIFA) for detection of circulating platelet antibody.
A. Kristensen   +4 more
semanticscholar   +1 more source

Platelets and Antiphospholipid Antibodies

Lupus, 1996
The involvement of platelets in the antiphospholipid syndrome is complex and the full pathogenic significance is not fully understood. The binding of aPL antibodies to the platelet membrane may result in the thrombopenia and further haemostatic activation.
openaire   +2 more sources

Platelet Migration Inhibition Test for Platelet Antibodies

International Archives of Allergy and Immunology, 1977
A simplified methodology and parameters associated with the performance of a platelet migration inhibition test for the detection of antiplatelet-associated antibodies is described.
J.A. Maples   +4 more
openaire   +1 more source

Anti-platelet Antibody Determination by Platelet Factor 3 Assay

American Journal of Clinical Pathology, 1976
Anti-platelet antibody determinations by a recently introduced platelet factor 3 assay (Pf-3 assay) were evaluated in 159 specimens from 95 patients who had low platelet counts. As a standard procedure, the 51Cr lysis test (51Cr test) was used. The 51Cr test and Pf-3 assay had an excellent correlation (results agreed for 80.5% of 159 specimens tested).
T, Okuno, D, Crockatt
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The Effect of Antihuman Platelet Antibodies on Human Platelets

Thrombosis and Haemostasis, 1979
The influence of an heterologous antihuman platelet serum (AS) was examined an immunological approach to investigate platelet function, as induces aggregation and release from platelets in citrate plasma. Neither thrombin nor complement were requirements, and inhibitors of ADP-(adenosine) and collagen-induced (aspirin) aggregation were only slightly ...
E Ali-Briggs   +3 more
openaire   +1 more source

Platelet antibodies in systemic lupus erythematosus

British Journal of Haematology, 1987
Summary. In systemic lupus erythematosus (SLE), the precise cause of the thrombocytopenia is unknown. Since platelet associated IgG is increased in many patients, it has been suggested that the destruction of platelets might be dependent on specific antibodies.In nine patients with SLE, platelet associated immunoglobulins were found together with free
C, Kaplan   +4 more
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Platelet antibodies in immune thrombocytopenia

Blood Reviews, 1992
Several tests to detect antibodies to platelets in patients with immune thrombocytopenia have been developed over the 40 years since it was first noted that this disorder was mediated by antiplatelet factors. Early tests were crude and not reproducible. A major landmark was the quantitation of IgG immunoglobulin on platelet membrane and the observation
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Are Platelet-Antibody Tests Worthwhile?

New England Journal of Medicine, 1987
This issue of the Journal contains a report by Lehman et al. on a patient with autoimmune thrombocytopenia and lymphoreticular malignant disease, in whom state-of-the-art in vitro serologic methods...
openaire   +2 more sources

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