Results 91 to 100 of about 932,176 (296)

Machine learning based prediction of platelet concentration from ROTEM measurements

Scientific Reports
Viscoelastic testing is an established standard in modern coagulation medicine, reducing transfusion needs. However, it does not provide direct information on platelet count.
Roxane Brooks, Matthias Noitz, Tina Tomić Mahečić, Diana Mühl, Ákos Kerekes, Gabor Nardai, Christa Kubasta, Mislav Kasalo, Mateja Ulamec, Alexander Maletzky, Janos Fazakas, Jens Meier   +11 more
doaj   +1 more source

Evaluation of Complete Blood Count Parameters and Hematological Inflammatory Indices at Diagnosis in Childhood Nephrotic Syndrome

Güncel Pediatri
Introduction: Nephrotic syndrome is associated with immüne inflammatory activation and alterations in platelet-related parameters. This study aimed to compare complete blood count parameters, platelet/mean platelet volüme related indicators, and ...
Okan Akacı, Muharrem Bostancı, Sümeyra İrem Duran   +2 more
doaj   +1 more source

Intracerebral Hemorrhage Induces Monocyte TNF Signaling in Patients That Is Suppressed by BAF312

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Intracerebral hemorrhage (ICH) causes high morbidity and mortality, with neurotoxic inflammation driven by infiltrating monocytes. This study is an in‐depth longitudinal examination of the immune response during the first week of ICH in the presence and absence of the immunomodulatory drug BAF312 (Siponimod).
Jonathan Howard DeLong, Sebastian Díaz‐Pérez, Kevin Navin Sheth, Jang‐Ho Cha, C. J. Malanga, Patricia G. M. Wagner, Nicole Pezous, Aurelie Hanin, Kyle B. Walsh, H. E. Hinson, Lauren Hachmann Sansing   +10 more
wiley   +1 more source

Platelet count and mean platelet volume in different asthma fenotypes [PDF]

, 2018
Aim of the study: to evaluate platelet count and mean platelet volume in the presence of different asthma fenotypes. Objectives: 1.To evaluate and compare platelet count and mean platelet volume in the blood of asthma patients and healthy subjects. 2. To
Barkauskienė, Gabrielė
core  

Re‐Purposing Sapropterin (Kuvan) for ACTA2‐Related Multisystemic Smooth Muscle Dysfunction Syndrome: A Translational Mechanistic and First‐In‐Human Therapeutic Report

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...
Moran Hausman‐Kedem, Noa Bielopolski, Vijai Krishnan, Shane Wald‐Altman, Shelly I Shrian, Omer Bar‐Yosef, Livia Kapusta, Claire Shamber, Patricia L. Musolino, Miguel Weil   +9 more
wiley   +1 more source

Climacteric Lowers Plasma Levels of Platelet-Derived Microparticles: A Pilot Study in Pre-versus Postmenopausal Women [PDF]

, 2012
Background: Climacteric increases the risk of thrombotic events by alteration of plasmatic coagulation. Up to now, less is known about changes in platelet-(PMP) and endothelial cell-derived microparticles (EMP). Methods: In this prospective study, plasma
Erhard Hiller, Sabine Roesner, Toth, Bettina, Katharina Nikolajek, Nikolajek, Katharina, Andreas Rank, Rank, Andreas, Nieuwland, Rienk, Hiller, Erhard, Rösner, Sabine, Roesner, Sabine, Bettina Toth, Rienk Nieuwland   +12 more
core   +1 more source

Metabolic and Fluid Biomarkers Support Microglia Activation in Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Amyotrophic lateral sclerosis is an incurable neurodegenerative disease involving motor neuron degeneration and metabolic and immune dysfunction. We combined clinical data, cerebrospinal fluid biomarkers and fluorodeoxyglucose positron emission tomography with magnetic resonance imaging to investigate the role of reactive microglia in disease ...
Matteo Zanovello, Francesca Serani, Alen Bebeti, Federica Paredi, Giulia Quadrio, Andrea Fortuna, Giacomo Maria Minicuci, Elena Pegoraro, Annachiara Cagnin, Diego Cecchin, Gianni Sorarù   +10 more
wiley   +1 more source

Platelet Count and Platelet Hematocrit Correlate to the Occurrence and Postoperative Recurrence in Intrauterine Adhesion Patients [PDF]

Yuhui Wei,1 Suli Kao,2 Mei Chen,3 Xuexue Yin4 1Department of Obstetrics and Gynecology, The First Hospital of Anhui University of Science & Technology, Huainan, Anhui, 232000, People’s Republic of China; 2Clinical Laboratory, The First Hospital of ...
Yin X, Kao S, Chen M, Wei Y
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The Importance of Platelet Glycoside Residues in the Haemostasis of Patients with Immune Thrombocytopaenia [PDF]

, 2021
Loss of sialic acid from the carbohydrate side chains of platelet glycoproteins can affect platelet clearance, a proposed mechanism involved in the etiopathogenesis of immune thrombocytopaenia (ITP).
García Barcenilla, Sara, Martín Salces, Mónica, Monzón Manzano, Elena, Justo Sanz, Raul, González Zorrilla, Elena, Ramírez-López, Andrés, Jiménez Yuste, Víctor, Arias-Salgado, Elena G, Cebanu, Tamara, Rivas Pollmar, María Isabel, Butta, Nora V, Álvarez Román, María Teresa, Acuña, Paula   +12 more
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Intravenous thrombolysis and platelet count [PDF]

Neurology, 2018
In the article “Intravenous thrombolysis and platelet count” by Gensicke et al.,1 there were a …
openaire   +2 more sources