Results 101 to 110 of about 378,593 (354)

ALS plasma biomarkers reveal neurofilament and pTau correlate with disease onset and progression

Annals of Clinical and Translational Neurology, EarlyView.
Abstract Objective We performed a pilot screen to assess the utility of the NULISA™ (Nucleic‐acid‐Linked Immuno‐Sandwich Assay) platform in the identification of amyotrophic lateral sclerosis (ALS) biomarkers. Methods Plasma from 86 individuals (48 ALS, 18 asymptomatic C9orf72 repeat expansion carriers (AsymC9), and 20 healthy controls) was analyzed ...
Eleanor V. Thomas, Changee Han, Woo Jae Kim, Seneshaw Asress, Yingjie Li, Jennifer A. Taylor, Marla Gearing, Christina N. Fournier, Zachary T. McEachin, Nicholas T. Seyfried, Jonathan D. Glass   +10 more
wiley   +1 more source

Identifying Hemostatic Thresholds in Cancer Patients Undergoing Coronary Angiography Based on Platelet Count and Thromboelastography

Frontiers in Cardiovascular Medicine, 2020
Objectives: To evaluate the role of platelet count and thromboelastogram (TEG) in the treatment of thrombocytopenic cancer patients with suspected coronary artery disease (CAD).Background: Cancer patients with CAD and thrombocytopenia are often treated ...
Ali M. Agha, Clarence Gill, Dinu Valentin Balanescu, Teodora Donisan, Nicolas Palaskas, Juan Lopez-Mattei, Saamir Hassan, Peter Y. Kim, Konstantinos Charitakis, Mehmet Cilingiroglu, Thein Hlaing Oo, Michael Kroll, Jean Bernard Durand, Cheryl Hirsch-Ginsberg, Konstantinos Marmagkiolis, Cezar Iliescu   +15 more
doaj   +1 more source

Is food intolerance a factor underlying chronic immunethrombocytopenia (ITP)? [PDF]

, 2017
Immune Thrombocytopenia is an organ specific autoimmune disorder. It was believed that food intolerance may be a factor in ITP, affecting platelet count. This study investigated whether dietary modification could lead to an increase in platelet count in
Achterbergh, Atkinson, Batty, Karpatkin, King, Kletter, Mullin, Suen, Zeng   +8 more
core   +2 more sources

Spurious Platelet Count [PDF]

New England Journal of Medicine, 2006
A previously healthy 48-year-old man was admitted for severe burns involving his face, thorax, and upper and lower limbs (45 percent of body-surface area) associated with an inhalation injury. The hemoglobin level was 12.3 g per deciliter, the hematocrit 37 percent, the mean corpuscular volume 93 μm3, the red-cell–distribution width 15.8 percent, and ...
Olivier Spertini, Michele Siegenthaler
openaire   +2 more sources

Clinical Trial Readiness in Limb Girdle Muscular Dystrophy R1 (LGMDR1): A GRASP Consortium Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Identifying functional measures that are both valid and reliable in the limb girdle muscular dystrophy (LGMD) population is critical for quantifying the level of functional impairment related to disease progression in order to establish clinical trial readiness in the context of anticipated therapeutic trials.
Stephanie M. Hunn, Lindsay N. Alfano, Aileen Jones, Amanda Butler, Linda P. Lowes, Megan A. Iammarino, Natalie F. Reash, Lindsay Pietruszewski, Sandhya Sasidharan, Melissa Currence, Jeffrey M. Statland, Talia Strahler, Robert Will, Matthew Wicklund, Stacy Dixon, Renee Augsburger, Tahseen Mozaffar, Katie M. Laubscher, Shelley R. H. Mockler, Katherine D. Mathews, Nikia Stinson, Doris G. Leung, Molly M. Stark, Rebecca A. Horton, Peter B. Kang, Meredith K. James, Amanda Clause, Conrad C. Weihl, Nicholas E. Johnson, GRASP‐LGMD Consortium   +29 more
wiley   +1 more source

The impact of thrombocytopenia on variceal bleeding in cirrhotic patients with transjugular intrahepatic portosystemic shunt

Scientific Reports, 2023
Thrombocytopenia is the most frequent haematologic disorder in patients with cirrhosis, and it is perceived as a contributory factor for bleeding events.
Yang Chen, Chongtu Yang, Songjiang Huang, Jiacheng Liu, Yingliang Wang, Chen Zhou, Tongqiang Li, Chaoyang Wang, Shuguang Ju, Yaowei Bai, Wei Yao, Bin Xiong   +11 more
doaj   +1 more source

Hubungan antara Derajat Keparahan Malaria dengan Jumlah Trombosit pada Pasien Malaria di RSU Bethesda Serukam Kabupaten Bengkayang Periode 2009 2012 [PDF]

, 2013
Background: Malaria is a parasitic haematological infectious diseasewhich could influence platelet count on the infected patient. Some studiesstated that platelet was involved in severe malaria pathogenesis.
Ivanna, I. (Ivanna)
core  

A Novel Protein‐Polysaccharide Oral Nanoemulsion Targeting Activated Hepatic Stellate Cells to Enhance the Therapeutic Effect of Pirfenidone on Fibrosis After Transarterial Chemoembolization for Liver Cancer

Advanced Functional Materials, EarlyView.
Transarterial Chemoembolization (TACE) may aggravate liver fibrosis. In this study, a novel oral targeting nanoemulsion is fabricated to enhance the therapeutic effect of antifibrotic drug‐pirfenidone (PFD) on fibrosis after TACE. Studies have shown that PFD nanoemulsion can enhance the oral liver targeting effect of PFD, and effectively improve the ...
Zhimei Cheng, Shan Xu, Yi Lei, Huizhou He, Runbin Sun, Xingle Jin, Cheneryu Huang, Yuhao Zheng, Jianqing Peng, Lei Tang, Peng Luo, Yi Chen, Shuai Zhang   +12 more
wiley   +1 more source

Transmission matrix of a uniaxial optically active crystal platelet [PDF]

, 2005
Expressions corresponding to the transmission of a uniaxial optically active crystal platelet are provided for an optical axis parallel and perpendicular to the plane of interface. The optical activity is taken into account by a consistent multipolar expansion of the crystal medium response due to the path of an electromagnetic wave. Numerical examples
arxiv   +1 more source

Electric Pulse Regulated MXene Based Nanozymes for Integrative Bioelectricity Immuno‐Cancer Therapy

Advanced Functional Materials, EarlyView.
MXenzyme‐mediated bioelectricity cancer therapy (MXenzyme‐BECT) enhances cancer cell death through irreversible depolarization, ion channel disruption, ROS generation, and immunogenic cell death. Computational simulations reveal the electrical mechanisms by which MXenzyme acts on single cells and support to predict treatment parameters. Next‐generation
Sanghee Lee, Seongchan Kim, Eui‐Sang Yu, Sian Lee, Min Jun Ko, Hyojin Lee, Dong‐Hyun Kim   +6 more
wiley   +1 more source