Results 201 to 210 of about 407,449 (356)

Targeting NRP1 in Endothelial Cells Facilitates the Normalization of Scar Vessels and Prevents Fibrotic Scarring

Advanced Science, EarlyView.
Scars exhibit vascular abnormal alterations, including upregulated NRP1 expression in endothelial cells, increased vascular density and branching, compromised vessel wall integrity, and incomplete pericyte coverage. Therapeutic targeting of NRP1 through hydrogel spray delivery offers a promising approach to normalize aberrant vasculature and prevent ...
Yu Wang, Xin Zhou, Min Liu, Meimei Huang, Peirong Chen, Xinying Li, Fangchao Xue, Wenyan Zhao, Di Liu, Lang Li, Yuangang Lu, Wen Zeng   +11 more
wiley   +1 more source

Never change a winning team-liver stiffness measurement and platelet count as key surrogates for clinically significant portal hypertension. [PDF]

Hepatobiliary Surg Nutr
Semmler G, Jachs M, Mandorfer M.
europepmc   +1 more source

RUNX2 Activation in Fibro/Adipogenic Progenitors Promotes Muscle Fibrosis in Muscular Dystrophy

Advanced Science, EarlyView.
This study revealed a novel role of the chemokine‐TGF‐β1‐RUNX2 axis in determining the fate of FAP differentiation and modulating muscle fibrosis in patients and mice with muscular dystrophies. ABSTRACT Clinical evidence indicates concurrent muscle inflammation and fibrosis in muscular dystrophies (MDs); however, the molecular mechanisms underlying ...
Pengkai Wu, Zehua Zhang, Kai Zheng, Ziqi Zhu, Yong Zhu, Abdukahar Kiram, Lei Zhao, Huihui Chen, Zhu Xu, Xihua Li, Beicheng Sun, Zhijian Li, Dengqiu Xu   +12 more
wiley   +1 more source

Influence of age and sex on platelet count: Implications for optimizing growth factor-rich plasma preparation. [PDF]

J Clin Exp Dent
Sánchez-Pérez A, Palma-Sánchez A, Jornet-García A, Moya-Villaescusa MJ, Montoya-Carralero JM.   +4 more
europepmc   +1 more source

Reduced platelet count, but no major platelet function abnormalities, are associated with loss-of-function ATP-binding cassette-1 gene mutations [PDF]

, 2017
Pietro Minuz, Alessandra Meneguzzi, Eti Alessandra Femia, Cristiano Fava, Stefano Calabria, Mariangela Scavone, Donatella Benati, Giovanni Poli, Carlo Zancanaro, S. Calandra, Tiziano Lucchi, Marco Cattaneo   +11 more
openalex   +1 more source

A Biomarker‐Driven Ovary–Endometrium Organ‐on‐a‐Chip Mimicking 3D Multicellular Complexity and Menstrual Cyclicity for Predicting Reproductive Toxicity

Advanced Science, EarlyView.
We present a dual‐organ, biomarker‐integrated ovaryendometrium organ‐on‐a‐chip that recapitulates 3D tissue complexity, menstrual cycle dynamics, and hormonal crosstalk. This platform enables real‐time, cell‐typespecific fluorescent readouts of reproductive toxicity using ANGPTL4 and SERPINB2 as early‐response reporters.
Soo‐Rim Kim, Eun‐kyung Min, Choon‐Mi Lee, Chan Hum Park, Byung‐Chul Oh, YunJae Jung, In‐Sun Hong   +6 more
wiley   +1 more source

Effect of transjugular intrahepatic portosystemic shunt on platelet count and exact spleen volume segmented on computed tomography. [PDF]

Acta Radiol Open
Yerdelen SS, Maasoumy B, Hinrichs JB, Meyer BC, Wacker FK, Meine TC.   +5 more
europepmc   +1 more source

Pretreatment platelet count and neutrophil/lymphocyte ratio are predictive markers for carboplatin plus pemetrexed therapy-induced thrombocytopenia [PDF]

Sarah Hamed Abd Alsaheb, S. Hasan
openalex   +1 more source

Correction to: The impact of helicobacter pylori eradication on platelet counts of adult patients with idiopathic thrombocytopenic purpura [PDF]

, 2019
Sara Aljarad, Ahmad Alhamid, Ahmad Sankari Tarabishi, Ameen Suliman, Ziad Aljarad   +4 more
openalex   +1 more source

Combination of Albumin-Bilirubin Grade and Platelet Count as a Predictor of Esophageal Varices’ Presence and Grading in Egyptian Patients with HCV Related Cirrhosis

, 2022
Amera Esam AbdElmoneim Moharm, Ferial El-Kalla, Abdelrahman Kobtan, Walaa Elkhalawany   +3 more
openalex   +1 more source