Results 211 to 220 of about 378,593 (354)

Trifunctional Sialylation‐Based SF‐ZIF@NA Hydrogel for Selective Osteoclast Inhibition and Enhanced Bone‐Vessel Regeneration in Osteoporotic Bone Defects

Advanced Science, EarlyView.
This study introduces the SF‐ZIF@NA hydrogel system for osteoporotic bone defect treatment. The hydrogel inhibits osteoclast fusion by removing sialic acid and preserves the anabolic function of precursor osteoclasts (pOCs). It also releases Zn2⁺ in acidic conditions, promoting osteogenesis and angiogenesis.
Zhengrong Chen, Wenxin Yang, Yong Tang, Qianqian Dong, Kui Huang, Jiulin Tan, Jie Zhang, Juan Cai, Qixiu Yu, Qijie Dai, Jianzhong Xu, Shuquan Guo, Ce Dou, Fei Luo   +13 more
wiley   +1 more source

Cost‐effectiveness of second‐line therapies in adults with chronic immune thrombocytopenia

American Journal of Hematology, Volume 98, Issue 1, Page 122-130, January 2023., 2023
Abstract Major options for second‐line therapy in adults with chronic immune thrombocytopenia (ITP) include splenectomy, rituximab, and thrombopoietin receptor agonists (TRAs). The American Society of Hematology guidelines recommend rituximab over splenectomy, TRAs over rituximab, and splenectomy or TRAs while noting a lack of evidence on the cost ...
George Goshua, Pranay Sinha, Natalia Kunst, Lauren Pischel, Alfred Ian Lee, Adam Cuker   +5 more
wiley   +1 more source

Platelet Count at Diagnosis Is Associated with Endoscopic Activity in Pediatric Patients with Crohn's Disease. [PDF]

Pediatr Gastroenterol Hepatol Nutr
Lee SY.
europepmc   +1 more source

Disruption of the eEF1A1/ARID3A/PKC‐δ Complex by Neferine Inhibits Macrophage Glycolytic Reprogramming in Atherosclerosis

Advanced Science, EarlyView.
The eEF1A1/ARID3A/PKC‐δ complex critically regulates macrophage glycolytic reprogramming in atherosclerosis by mediating ARID3A phosphorylation and nuclear translocation, thereby driving ENO2 transcriptional activation. Neferine targets eEF1A1 to disrupt the eEF1A1/ARID3A/PKC‐δ complex to inhibit ENO2‐mediated macrophage glycolytic reprogramming in ...
Baoping Xie, Li‐Wen Tian, Chenxu Liu, Jiahua Li, Xiaoyu Tian, Rong Zhang, Fan Zhang, Zhongqiu Liu, Yuanyuan Cheng   +8 more
wiley   +1 more source

Combining CD34+ stem cell selection with prophylactic pathogen and leukemia directed T‐cell immunotherapy to simultaneously reduce graft versus host disease, infection, and leukemia recurrence after allogeneic stem cell transplant

American Journal of Hematology, Volume 98, Issue 1, Page 159-165, January 2023., 2023
Donor stem cell product undergoes CD34 stem cell selection. CD34 positive stem cells are used for transplantation. Pathogen‐ and leukemia‐specific T‐cells are manufactured from CD34 negative fraction and infused prophylactically 21 days after transplant.
David J. Gottlieb, Gaurav Sutrave, Wei Jiang, Selmir Avdic, Janine A. Street, Renee Simms, Leighton E. Clancy, Vicki Antonenas, Brian S. Gloss, Caroline Bateman, David C. Bishop, Kenneth P. Micklethwaite, Emily Blyth   +12 more
wiley   +1 more source

Letter to the Editor on "The associations among platelet count, mean platelet volume, and erectile dysfunction: an observational and Mendelian randomization study". [PDF]

Sex Med
Fang Y, Chen S, Huang C, Cheng B.
europepmc   +1 more source

Platelet count may predict abnormal bleeding time among pregnant women with hypertension and preeclampsia [PDF]

, 2001
R. J. McDonagh, Joel G. Ray, Robert Burrows, Elizabeth Burrows, Marian J. Vermeulen   +4 more
openalex   +1 more source

Electroactive Electrospun Nanofibrous Scaffolds: Innovative Approaches for Improved Skin Wound Healing

Advanced Science, EarlyView.
This review explores the potential of electroactive electrospun nanofibrous (EEN) scaffolds for enhanced skin wound healing. It discusses how a variety of electroactive materials can be prepared into EEN scaffolds via electrospinning technology, and their applications in various wound types. The review provides insights into the future perspectives for
Yang Zhang, Zhiyuan Zheng, Shilu Zhu, Liang Xu, Qingdong Zhang, Jie Gao, Min Ye, Shuwei Shen, Jinyu Xing, Ming Wu, Ronald X. Xu   +10 more
wiley   +1 more source

Bidirectional relationship between platelet count and skin cancer: tumor drug resistance mechanisms. [PDF]

Discov Oncol
Guo C, Deng J, Wen T, Li J, Zeng P, Liang C.   +5 more
europepmc   +1 more source

Preliminary report: effects of interleukin-1 on platelet counts

, 1990
Anand Shanker Tewari, H. Fletcher Starnes, William Buhles   +2 more
openalex   +1 more source