Results 21 to 30 of about 266,199 (261)

Gender-based differences in platelet function and platelet reactivity to P2Y12 inhibitors.

PLoS ONE, 2019
BACKGROUND:Gender influences platelet biology. Women have a larger platelet count, but gender-based differences in platelet function remain debated.
Marco Ranucci, Tommaso Aloisio, Umberto Di Dedda, Lorenzo Menicanti, Carlo de Vincentiis, Ekaterina Baryshnikova, Surgical and Clinical Outcome REsearch (SCORE) group   +6 more
doaj   +1 more source

White blood cell count, sex and age are major determinants of heterogeneity of platelet indices in an adult general population: results from the MOLI-SANI project

Haematologica, 2011
Background The understanding of non-genetic regulation of platelet indices - platelet count, plateletcrit, mean platelet volume, and platelet distribution width - is limited.
Iolanda Santimone, Augusto Di Castelnuovo, Amalia De Curtis, Maria Spinelli, Daniela Cugino, Francesco Gianfagna, Francesco Zito, Maria Benedetta Donati, Chiara Cerletti, Giovanni de Gaetano, Licia Iacoviello   +10 more
doaj   +1 more source

A The ratio of neutrophils l and the mean platelet volume to platelet count ratio as risk factors for febrile convulsions in Zakho

Zanco Journal of Medical Sciences
Background and objective: The most prevalent cause of convulsions in young children is febrile convulsions. The ratio of neutrophils to lymphocytes (NLR), the mean platelet volume (MPV), and the platelet count are indicators of inflammation.
Sherzad A. Mosa, Akrem M. Atrushi, Farhad Shaker Armishty, Mehvan Sh. Abdulrahman   +3 more
doaj   +1 more source

Impact of platelet count on results obtained from multiple electrode platelet aggregometry (Multiplate™)

European Journal of Medical Research, 2010
Objectives Use of potent antiplatelet drugs requires evaluation of platelet function. While platelet function in elective cases is usually assessed in a central laboratory environment, there is also an urgent need for rapid perioperative point-of-care ...
Hanke AA, Roberg K, Monaca E, Sellmann T, Weber CF, Rahe-Meyer N, Görlinger K   +6 more
doaj   +1 more source

Erythrocytes and Platelets: A Critical Analysis of their Ontogenic Relationship through Automated Parameters [PDF]

Journal of Clinical and Diagnostic Research, 2017
Introduction: Erythrocytes and platelets share an intimate development history, due to which special interest is centered on their relationship. Mature Red Blood Cells (RBCs) and platelets show a similar physiological rhythm, and are concurrently ...
Deepak Kumar, Padma Priya Kasukurti, Srinivasa Murthy   +2 more
doaj   +1 more source

NRASQ61R Expression in Lymphatic Endothelial Cells Causes Enlarged Vessels, Hemorrhagic Chylous Effusions, and High Mortality in a Mouse Model of Kaposiform Lymphangiomatosis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Kaposiform lymphangiomatosis (KLA) is an aggressive complex lymphatic anomaly. Patients exhibit malformed lymphatic vessels and often develop hemorrhagic effusions and elevated angiopoietin‐2 (Ang‐2) levels. A somatic NRAS p.Q61R (NRASQ61R) mutation has been associated with KLA.
C. Griffin McDaniel, Patricia Pastura, Joshua P. Scallan, Timothy D. Le Cras   +3 more
wiley   +1 more source

Effects of the Fluid Replacement Method During Online Hemodiafiltration on the Solute Removal Performance and Biocompatibility Using the Asymmetric Cellulose Triacetate Membrane

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Pre‐dilution online hemodiafiltration (Pre‐HDF) is predominantly used in Japan, whereas post‐dilution online HDF (Post‐HDF) is more common in Europe. An asymmetric cellulose triacetate (ATA) membrane may improve biocompatibility.
Kenji Sakurai, Yoshitaka Kurihara, Fumi Yamauchi, Hiromi Hosoya, Takeshi Saito   +4 more
wiley   +1 more source

PLATELET COUNTS AND PLATELET FUNCTION [PDF]

Blood, 1946
Abstract Determinations of the platelet count, clot retraction, bleeding time, capillary fragility, and coagulation time were made in 64 normal subjects and in 404 patients suffering from various diseases. The normal values for the platelet count done by an experienced technician using the Rees and Ecker method were: mean,
PAUL M. AGGELER, JOAN HOWARD, S. P. LUCIA, EDITH MILLS   +3 more
openaire   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source