Results 211 to 220 of about 5,384,811 (279)

Development and validation of a model for stratifying haematological malignancy risk in primary care using basic blood tests

British Journal of Haematology, EarlyView.
Summary Haematological malignancies are rare in primary care and are hard to predict. Existing prediction models often require a specific working diagnosis and are based on extensive clinical information, access to which may be limited at initial work‐up in primary care.
Mathilde Egelund Christensen, Michael Charles Sachs, William Grant Dunn, Gustav Jonzon, Margit Kriegbaum, Bent Struer Lind, Jan Samuelsson, Kirsten Groenbaek, George Vassiliou, Christen Lykkegaard Andersen   +9 more
wiley   +1 more source

Triggering SORL1 Expression Restricts ccRCC Progression by Inducing Ubiquitination‐Mediated c‐Myc Degradation

Cancer Science, EarlyView.
Targeted triggering of SORL1 expression through a novel MPOC delivery system could inhibit ccRCC progression through binding to TRIM22 and further promoting ubiquitination‐mediated C‐MYC degradation, thereby facilitating the inhibition of oxidative phosphorylation through transcriptional repression of ACO2 and IDH2.
Keyi Wang, Wei Song, Qi Bai, Shaoze Shen, Xiao Lu, Chenxuan Su, Shi Yang, Yidi Wang, Yu Xia, Rui Zan, Shuai Jiang, Jianming Guo   +11 more
wiley   +1 more source

Red blood cell distribution width and platelet distribution width as a predictive marker in the diagnosis of malignant and benign causes of acute gastrointestinal bleeding. [PDF]

Medicine (Baltimore)
Onem S, Gulecoglu Onem MG.
europepmc   +1 more source

100 Years of von Willebrand Disease (VWD): Comparison of Historical and Contemporary von Willebrand Factor (VWF) Activity Assays in the Laboratory Identification of VWD

Haemophilia, EarlyView.
Abstract Introduction von Willebrand disease (VWD) is a prevalent bleeding disorder resulting from deficiencies and/or defects in von Willebrand factor (VWF). Accurately diagnosing VWD, particularly distinguishing between qualitative defects (types 2A, 2B, 2 M, and 2N) and quantitative defects (types 1 and 3), poses challenges that have significant ...
Emmanuel J. Favaloro, Sandya Arunachalam, Mahzuza Salwa, Ronny Vong, Leonardo Pasalic   +4 more
wiley   +1 more source

Prognostic value of mean platelet volume and platelet distribution width for the outcomes of patients with acute ST-segment elevation myocardial infarction undergoing percutaneous coronary intervention. [PDF]

Am J Transl Res
He B, Sun Q.
europepmc   +1 more source

Differentiating β‐Thalassaemia From Iron Deficiency: Performance and Cut‐Off Dependency of More Than 40 Red Cell Discrimination Indices in a Large German Cohort

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT Background Since the 1970s, more than 40 red blood cell–based formulas have been proposed to differentiate β‐thalassaemia trait (BTT) from iron deficiency (ID) and iron deficiency anaemia (IDA), the main causes of microcytic anaemia. In Germany, where haemoglobinopathies are rare in the autochthonous population but increasingly encountered due
Rafid Al‐Nabhan, Dani Hakimeh, Lena Oevermann   +2 more
wiley   +1 more source

Association between perioperative platelet distribution width changes and postoperative acute kidney injury in patients with renal insufficiency: a retrospective study. [PDF]

BMC Nephrol
Su Y, Xu X, Luo Z, Fang Y, Gong S, Teng J, Ding X, Xu J, Jiang W.   +8 more
europepmc   +1 more source

Alveolar Bone Regeneration Using 3D‐Printed, Patient‐Specific, Resorbable PCL Scaffold: Prospective Cohort Study

Journal of Clinical Periodontology, EarlyView.
ABSTRACT Aim To evaluate clinical feasibility of 3D‐printed, patient‐specific, polycaprolactone (PCL) resorbable scaffolds for staged alveolar ridge augmentation. Materials and Methods Ten patients requiring staged bone augmentation underwent digital planning to virtually reconstruct the defect to its original contour.
Jamil Alayan, Reuben Staples, Sašo Ivanovski   +2 more
wiley   +1 more source

The Potential Value of Mean Platelet Volume and Platelet Distribution Width as Inflammatory Indicators in Surgical Necrotizing Enterocolitis. [PDF]

J Inflamm Res
Zhang Y, Chen Y, Lv J, Xiang X, Wang P, Feng W, Guo Z.   +6 more
europepmc   +1 more source

Diagnostic model based on machine learning with multi‐feature analysis for diabetic peripheral neuropathy in type 2 diabetes: A single‐center retrospective study

Journal of Diabetes Investigation, EarlyView.
ABSTRACT Objective Diabetic peripheral neuropathy (DPN) is a common and serious complication of diabetes, which imposes a significant economic burden on both society and individuals. Therefore, early identification and diagnosis are crucial for the prevention and treatment of DPN.
Xi Zheng, Keke Yang, Ruyi Qu, Xiaomin Peng, Ling Yang   +4 more
wiley   +1 more source