Results 241 to 250 of about 5,384,811 (279)

Preclinical Target Animal Safety Evaluation of Veterinary Monoclonal Antibodies: Principles, Methods, and Interpretation

Journal of Veterinary Pharmacology and Therapeutics, EarlyView.
ABSTRACT Monoclonal antibodies (mAbs) represent a rapidly expanding pharmaceutical class in veterinary medicine, with several products now authorized for use in dogs and cats. Limited published articles and veterinarian exposure to the principles of drug development present challenges in interpreting published safety evaluations that inform product ...
Adam Werts, Matthew Kuhn, Lauren Bessey, Alicia Braxton Hickman, Emily Chory, John Mitchell, Kirby Pasloske   +6 more
wiley   +1 more source

Reviewing the benefits and clinical outcomes of oral fibroblasts over mesenchymal stem cells for repairing periodontal defects during or after orthodontic tooth movement

Periodontology 2000, EarlyView.
Abstract Orthodontic therapy applies forces to teeth, causing an inflammatory reaction in the periodontal ligament. This is repaired by remodeling of the periodontium, allowing tooth displacement. Although orthodontic therapy is mostly initiated during childhood and adolescence, the number of adults seeking this treatment is increasing as our society's
Ludovica Parisi, Eleni Mavrogonatou, Anton Sculean, Dimitris Kletsas, Martin Degen   +4 more
wiley   +1 more source

Soft‐tissue volume augmentation during early, delayed, and late dental implant therapy: A systematic review and meta‐analysis on professionally determined esthetics and self‐reported patient satisfaction on esthetics

Periodontology 2000, EarlyView.
Abstract The objective of the study was to assess the effect of soft‐tissue volume augmentation during early, delayed, and late dental implant therapy in terms of professionally determined esthetics and self‐reported patient satisfaction on esthetics. For this, a comprehensive electronic literature search was performed to identify randomized clinical ...
Ausra Ramanauskaite, Sofya Sadilina, Frank Schwarz, Emilio A. Cafferata, Franz J. Strauss, Daniel S. Thoma   +5 more
wiley   +1 more source

Long‐term clinical outcomes of periodontal regeneration of intrabony defects: A systematic review and meta‐analysis

Periodontology 2000, EarlyView.
Abstract This systematic review and meta‐analysis aimed to evaluate the long‐term clinical outcomes of regenerative procedures compared with access flap surgery for the treatment of intrabony defects, with a minimum follow‐up period of 5 years. A systematic review protocol following PRISMA guidelines was conducted.
Hom‐Lay Wang, Parham Hazrati, Javier Calatrava, Muhammad S. Saleh, Abdusalam E. Alrmali   +4 more
wiley   +1 more source

Long‐term stability of transcrestal sinus augmentation

Periodontology 2000, EarlyView.
Abstract Transcrestal sinus augmentation has emerged as a minimally invasive alternative to lateral window techniques for vertical bone augmentation in the edentulous maxilla. Since its early introduction and modification over the last several decades, this technique has demonstrated predictable outcomes for implant placement in regions with limited ...
Sandra H. Stuhr, Muhammad H. A. Saleh, Tiziano Testori, Hom‐Lay Wang, Ann M. Decker   +4 more
wiley   +1 more source

Long‐term stability of sinus complication management

Periodontology 2000, EarlyView.
Abstract Maxillary sinus augmentation shows a low incidence of complications and high clinical success due to favorable biological conditions and typically transient issues. Most complications are intraoperative, such as Schneiderian membrane perforation or hemorrhage, and are often resolved immediately.
Pablo Galindo‐Moreno, Tiziano Testori, Miguel Padial‐Molina, Allinson Olaechea, Francisco O'Valle, Pablo Galindo‐Fernandez   +5 more
wiley   +1 more source

Long‐term stability of vertical bone augmentation in implant dentistry: A domain‐based review

Periodontology 2000, EarlyView.
Abstract Objectives Vertical ridge deficiency remains one of the most challenging conditions in preimplant surgery. Several techniques aim to restore lost vertical alveolar height, each with specific indications and limitations. Although these procedures often yield favorable short‐term outcomes with stable bone levels, their long‐term performance is ...
Istvan Urban, Pablo Antonio López‐Galindo, Mahboube Hasheminasab, Sahar Baniameri, Alessandro Cucchi, Muhammad Saleh, Pietro Felice, Andrea Ravidà   +7 more
wiley   +1 more source

Understanding exosomes in facial esthetics and skin aging

Periodontology 2000, EarlyView.
Abstract Background Skin aging is a multifactorial process mediated by intrinsic (genetic and metabolic) and extrinsic (environmental) factors leading to functional and structural deterioration, including wrinkles, loss of collagen and elastin, as well as various pigmentation disorders.
Richard J. Miron, Catherine Davies, Anton Sculean, Paras Ahmad   +3 more
wiley   +1 more source

Understanding exosomes in regenerative dentistry

Periodontology 2000, EarlyView.
Abstract Background Regenerative dentistry is shifting from cell‐based strategies to cell‐free biologics capable of orchestrating intricate tissue repair. Exosomes, nanosized extracellular vesicles carrying bioactive molecular payloads, have emerged as central modulators of intercellular communication.
Paras Ahmad, Anton Sculean, Richard J. Miron   +2 more
wiley   +1 more source

Diagnostic Value of Red Blood Cell Distribution Width, Platelet Distribution Width, and Red Blood Cell Distribution Width to Platelet Ratio in Children With Hemophagocytic Lymphohistiocytosis [PDF]

Journal of Clinical Laboratory Analysis, 2021
AbstractBackgroundTo investigate whether red blood cell distribution width (RDW), platelet distribution width (PDW), and red blood cell distribution width to platelet ratio (RPR) can serve as biomarkers to distinguish hemophagocytic lymphohistiocytosis (HLH) from sepsis in children.MethodsThis is a retrospective study, involving 71 HLH patients, 105 ...
Ya Xi
exaly   +3 more sources