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Role of platelet parameters in thrombocytopenia

International Journal of Clinical and Diagnostic Pathology, 2019
Introduction: Modern day analyzers are generating a number of parameters which with time have gained a lot of clinical significance. The platelet indices have been investigated as prospective platelet activation markers. The aim of this study is to predict the relationship between platelet parameters and cause of thrombocytopenia and their role in ...
Dr. Deepthi P Kambi, Dr. Shabnam Roohi
openaire   +1 more source

The mitochondrial membrane potential in human platelets: a sensitive parameter for platelet quality

Transfusion, 2004
BACKGROUND:  Deterioration of platelet (PLT) quality during storage is accompanied by an increase in lactate production, indicating a decrease in mitochondrial function. In this study, the optimal conditions under which the fluorescent dye JC‐1 can be used to detect changes in mitochondrial function in PLTs were established.STUDY DESIGN AND METHODS ...
Verhoeven, Arthur J.   +3 more
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Platelet Parameters and Aggregation in Essential and Reactive Thrombocytosis

American Journal of Clinical Pathology, 1988
Platelet characteristics were assessed in 15 patients with essential thrombocytosis (ET), 89 patients with reactive thrombocytosis (RT), and 23 normal controls. A platelet volume distribution width (PDW) greater than or equal to 10.5 was found in 50%, 21%, and 14% of the three groups, respectively (P = 0.01 between patients with ET and patients with RT;
E, Sehayek   +4 more
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Automated Platelet-Sizing Parameters on a Normal Population

American Journal of Clinical Pathology, 1987
The quantitation of platelets in peripheral blood is a well-recognized tool. However, other platelet parameters that recently have become available on a routine basis with the introduction of automated cell sizers may become increasingly important in evaluating the integrity of the thrombocytic function.
S S, Graham, B, Traub, I B, Mink
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An important and overlooked parameter in platelet rich plasma preparation: The mean platelet volume

Journal of Cosmetic Dermatology, 2018
SummaryBackgroundThe platelets are the most heterogeneous cellular elements of the blood in size whereas larger platelets have more granules that make them more reactive rather than their smaller counterparts.ObjectivesThe aim of this study is to report the distribution of platelets in the plasma after centrifugation steps.MethodsTwelve healthy male ...
Kadri Ozer   +2 more
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Platelet count ratio (PCR) as an additional parameter in the quantitation of platelet aggregation in vitro

Thrombosis Research, 1980
Abstract An additional parameter, the platelet count ratio (PCR), has been introduced to describe further platelet aggregation as determined by nephelometric measurements. This parameter is the ratio of the count of individual platelets a specified time after the addition of an aggregating agent to the original platelet count of the plateletrich ...
K U, Benner   +3 more
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Platelet migration inhibition test for platelet antibodies. Parameters and simplified methodology.

International archives of allergy and applied immunology, 1977
A simplified methodology and parameters associated with the performance of a platelet migration inhibition test for the detection of antiplatelet-associated antibodies is described.
M, Nishiki   +4 more
openaire   +2 more sources

Comparison of platelet aggregation parameters and expression of platelet granule markers

Тромбоз, гемостаз и реология, 2019
Введение. Активация тромбоцитов стимулирует их агрегацию и ассоциированный с секрецией экзоцитоз внутриклеточных гранул. Агрегацию чаще всего изучают турбидиметрическим методом, а экзоцитоз гранул методом проточной цитофлуориметрии, определяя экспрессию их маркеров на поверхности тромбоцитов.
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Assessment of in vitro platelet activation by Advia 120 platelet parameters.

Laboratory hematology : official publication of the International Society for Laboratory Hematology, 2004
The Advia 120 Hematology System provides new platelet parameters that have been proposed as useful markers of platelet activation. The aim of this study was to investigate platelet parameter variations after adenosine diphosphate (ADP) activation of platelet-rich plasma (PRP) in vitro, with particular interest in the mean platelet component (MPC ...
A, Giacomini   +6 more
openaire   +1 more source

Investigating the influence of iron parameters in regulating platelet recovery in Apheresis Platelet Donors

Indian Journal of Hematology and Blood Transfusion
Introduction: The present study investigates changes in haematological parameters in the donor during apheresis and following donation. Effect of iron parameters in influencing platelet recovery was studied. Methods: Blood samples were collected in EDTA tubes for analyses of haematological parameters.
Ranita De   +4 more
openaire   +1 more source

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