BACKGROUND: Platelet parameters in steady-state sickle cell anemia (SCA) are affected by the red cell sickling, vaso-occlusion, and chronic hemolysis occasioned by the disease; and the occurrence of bone pain crises may further alter these parameters ...
Abubakar Umar Musa, Mohammed A Ndakotsu
doaj +1 more source
Structural identification of oxidized acyl-phosphatidylcholines that induce platelet activation [PDF]
Oxidation of low-density lipoprotein (LDL) generates proinflammatory and prothrombotic mediators that may play a crucial role in cardiovascular and inflammatory diseases.
Siedler, F. +3 more
core +1 more source
Platelet turnover in stable coronary artery disease - influence of thrombopoietin and low-grade inflammation. [PDF]
BACKGROUND: Newly formed platelets are associated with increased aggregation and adverse outcomes in patients with coronary artery disease (CAD). The mechanisms involved in the regulation of platelet turnover in patients with CAD are largely unknown. AIM:
Sanne Bøjet Larsen +3 more
doaj +1 more source
Evaluation of Platelets as Predictive Parameters in Dengue Fever [PDF]
Dengue is an arboviral disease and occurs in tropical countries where over 2.5 billion people are at risk of infection. Each year an estimated 100 million cases of dengue fever (DF) occur and between 2.5 and 5 lakh cases of dengue hemorrhagic fever (DHF) are reported to WHO.
Jayashree, K. +3 more
openaire +2 more sources
Kawasaki disease (KD) is the leading cause of acquired cardiovascular disease in children and is characterized by intense immune activation and platelet dysfunction.
Linjie Jiang +21 more
doaj +1 more source
Investigations into effects of 12-lipoxygenase and NADPH oxidase on platelet activity, and influences of dietary dark chocolate [PDF]
PhDPlatelets play a pivotal role in both normal hemostasis and pathological bleeding and importantly also contribute to the development of atherothrombosis.
Zain, Zetty Nadia Mohd
core +2 more sources
Immature Platelet Fraction: A Platelet Parameter With Significant Clinical Utility [PDF]
Mean platelet volume (MPV), platelet distribution width (PDW) and the calculated plateletcrit (PCT) are reported to be useful in thrombocytopenia to assess platelet regeneration in the marrow. Our hypothesis was that the immature platelet fraction (IPF) is the most significant platelet parameter in patients with thrombocytopenia.
Rekha Bhat, Swati Pai
openaire +1 more source
The role of platelet parameters in thrombosed hemorrhoids [PDF]
Abstract Objectives The most common disease of anus is hemorrhoids. The definition of external hemorrhoids suggests the acute phase, often characterized by thrombosis or edema. External thrombosed hemorrhoid is a specific complication. In this study, we aimed to investigate the effects of different platelet parameters in the presence of ...
Mutlu Sahin +4 more
openaire +4 more sources
Effect of montelukast on platelet activating factor- and tachykinin induced mucus secretion in the rat [PDF]
Background: Platelet activating factor and tachykinins (substance P, neurokinin A, neurokinin B) are important mediators contributing to increased airway secretion in the context of different types of respiratory diseases including acute and chronic ...
David A Groneberg +12 more
core +1 more source
Platelet monoamine oxidase activity in alcoholics with and without a family history of alcoholism [PDF]
A number of studies point at platelet monoamine oxidase (MAO) activity being reduced in alcoholics with a family history of drinking, this being a possible vulnerability marker for alcoholism.
Bondy, Brigitta +11 more
core +1 more source

