Results 131 to 140 of about 102,294 (349)

Difficulties in evaluating the efficacy of antiplatelet therapy in clinical practice

open access: yesТерапевтический архив, 2009
Aim. To evaluate platelet activity changes in patients with coronary artery disease (CAD) treated with aspirin, clopidogrel and combination of these drugs; to estimate the rate of resistance of CAD patients to antiplatelet treatment. Material and methods.
L I Buryachkovskaya   +7 more
doaj  

MicroRNA-223-3p is a determinant of platelet procoagulant activity

open access: yesBlood Advances
: MicroRNAs (miRNAs) are regulators of platelet function and may, thus, contribute to interindividual variability in platelet reactivity. MicroRNA-223-3p (miR-223-3p) is the most abundant of the platelet-derived miRNAs.
Julia Charlon-Gay   +5 more
doaj   +1 more source

Effect on Platelet Reactivity From a Prasugrel Loading Dose After a Clopidogrel Loading Dose Compared With a Prasugrel Loading Dose Alone [PDF]

open access: bronze, 2013
Jean G. Diodati   +8 more
openalex   +1 more source

Injectable Stimuli‐Responsive Amphiphilic Hydrogel for Rapid Hemostasis, Robust Tissue Adhesion, and Controlled Drug Delivery in Trauma and Surgical Care

open access: yesAdvanced Healthcare Materials, EarlyView.
Fast‐acting hydrogel seals bleeding wounds as the illustrated injectable, pH‐responsive network rapidly gels in situ to stop hemorrhage, adhere strongly to wet tissue, and release antibiotics in a controlled, pH‐dependent manner. The material withstands high pressures, shows excellent biocompatibility, and degrades safely, offering a versatile platform
Arvind K. Singh Chandel   +5 more
wiley   +1 more source

Clopidogrel discontinuation and platelet reactivity following coronary stenting. [PDF]

open access: yes, 2010
Aims: Antiplatelet therapy with aspirin and clopidogrel are recommended for 1 year after drug-eluting stent (DES) implantation or myocardial infarction. However, the discontinuation of antiplatelet therapy has become an important issue as recent studies ...
Dicker, Patrick   +6 more
core   +1 more source

Aerobic exercise training lowers platelet reactivity and improves platelet sensitivity to prostacyclin in pre‐ and postmenopausal women [PDF]

open access: bronze, 2017
Martina H. Lundberg Slingsby   +6 more
openalex   +1 more source

An In Situ Embedded B‐MOF Sponge With Shape‐Memory for All‐in‐One Diabetic Wound Therapy

open access: yesAdvanced Healthcare Materials, EarlyView.
A smart shape‐memory sponge dressing (P1A3@B‐MOF) is developed for accelerated diabetic wound healing. It achieves pH‐responsive corelease of Zn2+ and salvianolic acid B, synergistically providing antibacterial action, repolarizing macrophages to the M2 phenotype, and promoting angiogenesis.
Hai Zhou   +11 more
wiley   +1 more source

RGS10 shapes the hemostatic response to injury through its differential effects on intracellular signaling by platelet agonists. [PDF]

open access: yes, 2018
Platelets express ≥2 members of the regulators of G protein signaling (RGS) family. Here, we have focused on the most abundant, RGS10, examining its impact on the hemostatic response in vivo and the mechanisms involved.
Brass, Lawrence F.   +7 more
core   +1 more source

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