Results 21 to 30 of about 102,294 (349)

Biologic Nanoparticles and Platelet Reactivity [PDF]

open access: yesNanomedicine, 2009
Nanosized particles (NPs) enriched in hydroxyapatite and protein isolated from calcified human tissue accelerate occlusion of endothelium-denuded arteries when injected intravenously into rabbits. Since platelet aggregation and secretory processes participate in normal hemostasis, thrombosis and vascular remodeling, experiments were designed to ...
Virginia M, Miller   +6 more
openaire   +2 more sources

Circulating microRNAs as biomarkers and mediators of platelet activation

open access: yesPlatelets, 2022
Platelets are essential mediators of physiological hemostasis and pathological thrombosis. Currently available tests and markers of platelet activation did not prove successful in guiding treatment decisions for patients with cardiovascular disease ...
Clemens Gutmann, Manuel Mayr
doaj   +1 more source

Platelet reactivity expressed as a novel platelet reactivity score is associated with higher inflammatory state after coronary artery bypass grafting

open access: yesArchives of Medical Science, 2019
Introduction Despite therapy, patients operated using a cardiopulmonary bypass demonstrate increased platelet aggregation, which rebounds to above preoperative levels.
Mirosław Wilczyński   +4 more
doaj   +1 more source

Unfavorable Changes of Platelet Reactivity on Clopidogrel Therapy Assessed by Impedance Aggregometry Affect a Larger Volume of Acute Ischemic Lesions in Stroke

open access: yesDiagnostics, 2021
Background: High on-treatment platelet reactivity or its equivalent—resistance to the antiplatelet agent—significantly reduces the efficacy of the therapy, contributing to a negative impact on stroke course.
Adam Wiśniewski   +7 more
doaj   +1 more source

Novel Strategies for Assessing Platelet Reactivity [PDF]

open access: yesFuture Cardiology, 2016
There are many approaches to assessing platelet reactivity and many uses for such measurements. Initially, measurements were based on the ability of platelets separated from other blood cells to aggregate together following activation with an appropriate 'aggregating agent'.
Algahtani, Mohammad, Heptinstall, Stan
openaire   +3 more sources

Impact of Reticulated Platelets on Platelet Reactivity in Neonates [PDF]

open access: yesJournal of Cardiovascular Pharmacology and Therapeutics, 2021
Neonatal megakaryopoiesis and platelet turnover form a developmentally unique pattern by generating a pool of newly released reticulated platelets from the bone marrow into the circulation. Reticulated platelets are more reactive and hyperaggregable compared to mature platelets, due to their high residual mRNA content, large size, increased expression
openaire   +2 more sources

Apixaban Enhances Endogenous Fibrinolysis in Patients with Atrial Fibrillation [PDF]

open access: yes, 2019
© The Author(s) 2019. Published by Oxford University Press on behalf of the European Society of Cardiology.AIMS: Approximately 20% of ischaemic stroke patients exhibit spontaneous arterial recanalization, attributable to endogenous fibrinolysis, which ...
Arachchillage, Deepa RJ   +7 more
core   +3 more sources

Elevated Baseline Serum Fibrinogen: Effect on 2-Year Major Adverse Cardiovascular Events Following Percutaneous Coronary Intervention. [PDF]

open access: yes, 2017
BackgroundElevated fibrinogen is associated with short-term major adverse cardiovascular events (MACE) after percutaneous coronary intervention, but the relation with late MACE is unknown.Methods and resultsBaseline demographics and 2-year MACE were ...
Ang, Lawrence   +7 more
core   +1 more source

Increased platelet reactivity after heart transplantation

open access: yesTransplantation Reports, 2020
Background: The role of antiplatelet therapy following heart transplantation (HT) is unclear. Ex-vivo studies suggest increased platelet hyperaggregability after HT.
Natasha Aleksova   +4 more
doaj   +1 more source

Serotonin reuptake inhibitors and cardiovascular disease [PDF]

open access: yes, 2005
Selective serotonin re-uptake inhibiting drugs (SSRIs) are widely used for endogenous depression. In addition to depleting the nerve terminals of serotonin they also lower blood platelet serotonin levels.
Belcher, P.R.   +2 more
core   +1 more source

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