Results 21 to 30 of about 102,294 (349)
Biologic Nanoparticles and Platelet Reactivity [PDF]
Nanosized particles (NPs) enriched in hydroxyapatite and protein isolated from calcified human tissue accelerate occlusion of endothelium-denuded arteries when injected intravenously into rabbits. Since platelet aggregation and secretory processes participate in normal hemostasis, thrombosis and vascular remodeling, experiments were designed to ...
Virginia M, Miller +6 more
openaire +2 more sources
Circulating microRNAs as biomarkers and mediators of platelet activation
Platelets are essential mediators of physiological hemostasis and pathological thrombosis. Currently available tests and markers of platelet activation did not prove successful in guiding treatment decisions for patients with cardiovascular disease ...
Clemens Gutmann, Manuel Mayr
doaj +1 more source
Introduction Despite therapy, patients operated using a cardiopulmonary bypass demonstrate increased platelet aggregation, which rebounds to above preoperative levels.
Mirosław Wilczyński +4 more
doaj +1 more source
Background: High on-treatment platelet reactivity or its equivalent—resistance to the antiplatelet agent—significantly reduces the efficacy of the therapy, contributing to a negative impact on stroke course.
Adam Wiśniewski +7 more
doaj +1 more source
Novel Strategies for Assessing Platelet Reactivity [PDF]
There are many approaches to assessing platelet reactivity and many uses for such measurements. Initially, measurements were based on the ability of platelets separated from other blood cells to aggregate together following activation with an appropriate 'aggregating agent'.
Algahtani, Mohammad, Heptinstall, Stan
openaire +3 more sources
Impact of Reticulated Platelets on Platelet Reactivity in Neonates [PDF]
Neonatal megakaryopoiesis and platelet turnover form a developmentally unique pattern by generating a pool of newly released reticulated platelets from the bone marrow into the circulation. Reticulated platelets are more reactive and hyperaggregable compared to mature platelets, due to their high residual mRNA content, large size, increased expression
openaire +2 more sources
Apixaban Enhances Endogenous Fibrinolysis in Patients with Atrial Fibrillation [PDF]
© The Author(s) 2019. Published by Oxford University Press on behalf of the European Society of Cardiology.AIMS: Approximately 20% of ischaemic stroke patients exhibit spontaneous arterial recanalization, attributable to endogenous fibrinolysis, which ...
Arachchillage, Deepa RJ +7 more
core +3 more sources
Elevated Baseline Serum Fibrinogen: Effect on 2-Year Major Adverse Cardiovascular Events Following Percutaneous Coronary Intervention. [PDF]
BackgroundElevated fibrinogen is associated with short-term major adverse cardiovascular events (MACE) after percutaneous coronary intervention, but the relation with late MACE is unknown.Methods and resultsBaseline demographics and 2-year MACE were ...
Ang, Lawrence +7 more
core +1 more source
Increased platelet reactivity after heart transplantation
Background: The role of antiplatelet therapy following heart transplantation (HT) is unclear. Ex-vivo studies suggest increased platelet hyperaggregability after HT.
Natasha Aleksova +4 more
doaj +1 more source
Serotonin reuptake inhibitors and cardiovascular disease [PDF]
Selective serotonin re-uptake inhibiting drugs (SSRIs) are widely used for endogenous depression. In addition to depleting the nerve terminals of serotonin they also lower blood platelet serotonin levels.
Belcher, P.R. +2 more
core +1 more source

