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Perioperative Platelet Reactivity and the Effects of Clonidine
Anesthesiology, 1993Increased postoperative platelet reactivity may contribute to arterial thrombotic complications following surgery. alpha 2 Agonists, which are being used increasingly to blunt the stress response of surgery, increase platelet aggregation in vitro. We compared perioperative changes in platelet reactivity in 21 patients receiving either clonidine or ...
Alex Siedler+7 more
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The Platelet Reactivity of Collagen Type VI
Collagen and Related Research, 1985Collagen type VI in native (undenatured or triple-helical) form has been shown, like collagen types I-V, alpha 1(I) trimer and alpha 2(I) trimer, to possess platelet reactivity provided that essential quaternary structural needs are first satisfied. Thus platelet aggregation was induced by the collagenous domain of collagen type VI, isolated free of ...
Robert D. Young+2 more
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A COMPARATIVE STUDY OF PLATELET REACTIVITY IN ARTHRITIS*
Annals of the New York Academy of Sciences, 1981We utilized a standardized in vitro method which employs transmission electron microscopy to monitor the degree of surface activation (cytoplasmic spreading) and amount of aggregation displayed by platelet populations from 314 patients with one of five distinct rheumatic diseases and from 72 normal subjects.
Kumar Venkatasubramanian+6 more
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Endothelium as a Modulator of Platelet Reactivity
1985The pathways through which endothelial cells can modulate platelet reactivity (whether directly via the secretion of agents that affect platelet function or indirectly through the regulation of coagulation or vascular tone) are sufficiently varied and complex that the direction of individual reactions can be altered as the homeostatic balance requires--
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Nutritional zinc increases platelet reactivity
American Journal of Hematology, 1991AbstractAfter ingestion of 220 mg zinc sulfate, platelet aggregation was evaluated at various time intervals (i.e., T = 0, 1, and 3 hr) and the autologous plasma analyzed by atomic absorption analysis. The zinc levels increased maximally some 0.4 ± 0.2 μg/ml within 3 hr after ingestion, which tor the entire blood pool corresponds to only 5% of the ...
Judit Krugliak+2 more
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Adrenoreceptors, platelet reactivity and clopidogrel resistance
Thrombosis and Haemostasis, 2008Thromb Haemost 2008; 100: 729–730 Platelet activation plays a central role in haemostasis and thrombosis. Antiplatelet therapy is considered to be the ‘cornerstone’in the prevention and treatment of thrombotic diseases such as coronary artery disease (CAD), stroke and peripheral arterial disease (PAD).
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New approaches for measurement of platelet reactivity
Blood, 2012In a highly interesting, intricate, and novel paper in this issue of Blood, Fung and colleagues have extended their previous pioneering studies and now reveal that molecules such as ATP can promote platelet activation through the P2X1 receptor ...
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Platelet‐to‐lymphocyte ratio is associated with prognosis in patients with coronavirus disease‐19
Journal of Medical Virology, 2020Zhi Guo, Xiao Chen, Hua Ren
exaly
Age dependence of platelet reactivity
Thrombosis Research, 1992M. Penka, M. Pařízek
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