Results 101 to 110 of about 206,755 (278)

Application and analysis of compatible platelets matching via antigen avoidance

open access: yesZhongguo shuxue zazhi
[Objective] To investigate the application of antigen avoidance pattern for compatible platelets matching. [Methods] Samples from two patients with immune-mediated platelet transfusion refractoriness were screened for platelet antibodies using solid ...
WU Shaoyun   +3 more
doaj   +1 more source

A subset of anti-HLA antibodies induces FcγRIIa-dependent platelet activation

open access: yesHaematologica, 2018
HLA antibodies are associated with refractoriness to platelet transfusion, leading to rapid platelet clearance, sometimes coinciding with clinical side effects such as fever and chills.
Maaike Rijkers   +11 more
doaj   +1 more source

FREQUENCY AND CHARACTERIZATION OF PLATELET- SPECIFIC ANTIBODIES IN PATIENTS WHO RECEIVED MULTIPLE PLATELET TRANSFUSIONS [PDF]

open access: yes, 2000
Multiple platelet transfusions can induce alloimmunization. Alloimmunization involving platelet membrane antigens has been characterized by failure to achieve the expected post-transfusion platelet levels; this is a clinical status frequently referred to
Susannah Whay-Sue Lin   +3 more
core  

Clinical Experience With Eliglustat in Children With Gaucher Disease Type 1

open access: yes
American Journal of Medical Genetics Part A, EarlyView.
Erika R. Vucko   +6 more
wiley   +1 more source

Recombinant activated factor VIIa for severe postpartum hemorrhage in Africa: Evidence, appropriate use, and research priorities—A narrative review

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Postpartum hemorrhage (PPH) accounts for 30%–50% of maternal mortality in Africa and occurs in the context of pre‐existing anemia, limited blood product availability, delayed recognition, and constrained referral systems. Although bundle‐based care (E‐MOTIVE), early tranexamic acid (TXA), and uterotonics have substantially improved outcomes, a
Johnny Mahlangu   +3 more
wiley   +1 more source

Ovarian Cancer: Epidemiology, Disease Mechanisms, New Diagnosis and Treatment Strategies, and Research Directions

open access: yesiNew Medicine, EarlyView.
ABSTRACT Ovarian cancer (OC) continues to be the deadliest gynecological malignancy and a significant cause of cancer‐related mortality among women worldwide. Standard treatment strategies typically entail platinum‐based chemotherapy in conjunction with cytoreductive surgery.
Zunera Khalid   +4 more
wiley   +1 more source

Evaluation of the platelet cross-matching in oncology patients

open access: yesGlobal Journal of Transfusion Medicine, 2016
Context: Platelet transfusion is an essential part of managing cancer. Refractoriness to platelet transfusion poses great challenge in the treatment of thrombocytopenic patients.
Sadhana Mangwana, Nikhil Simon
doaj   +1 more source

Dual biologic therapy in inflammatory bowel disease, a retrospective cohort study of vedolizumab and anti‐tumor necrosis factor alpha therapy in children

open access: yesJournal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives Despite advances in pediatric inflammatory bowel disease (PIBD) with biologics, remission rates remain at 47%–60% with loss‐of‐response rates at 60%–68%. Evidence for efficacy of dual biologic therapy (DBT) with anti‐tumor necrosis factor alpha therapy (anti‐TNF‐α)‐ vedolizumab (VDZ) for children refractory to anti‐TNF‐α therapy is ...
Jonathan E. M. O'Donnell   +6 more
wiley   +1 more source

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