Results 161 to 170 of about 99,958 (297)

Harnessing blood clot as a native scaffold for orchestrating tissue repairs and regeneration

BMEMat, EarlyView.
The blood clot, owing to its dynamic composition and unique microenvironment, holds significant yet underappreciated potential for tissue engineering. This review systematically summarizes the pathophysiology of clot formation, the key regulatory factors shaping its microenvironment, and its applications in both pre‐clinical and clinical settings ...
Gao‐peng Dang, Yu‐zhu Wang, Yi‐fei Wang, Que Bai, Jia‐xin Hao, Zhi‐ting Li, Xiao‐qing Cao, Yu Wei, Yue Feng, Ji‐hua Chen, Franklin R. Tay, Rui‐bing Wang, Jun‐ting Gu, Li‐na Niu   +13 more
wiley   +1 more source

Virtual Twin Approach Using Physiologically Based Pharmacokinetic Modeling to Support Precision Dosing of Valproic Acid in Geriatric Patients

Clinical Pharmacology &Therapeutics, EarlyView.
Personalized dosing is particularly important for drugs with narrow therapeutic indices in geriatric patients, who exhibit substantial physiological variability and limited pharmacokinetic (PK) evidence to guide individualized dose selection. Valproic acid (VPA) is an effective treatment option for bipolar disorder in older adults, yet dosing largely ...
Yoo Jin Jang, Dong‐Gyu Heo, Eunjin Hong   +2 more
wiley   +1 more source

Research Progress on Platelet-Rich Plasma (PRP) in the Treatment of Androgenetic Alopecia. [PDF]

J Cosmet Dermatol
Zhong Z, Luo L, Zhao L, Yue X, Lu Y.
europepmc   +1 more source

Tellurium Electrochemistry: From Mechanistic Analysis in Diverse Electrolytic Media to Advanced Energy Storage Applications

ENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
As a metalloid with broad prospects in advanced applications, Te has not been fully clarified in terms of its intricate electrochemical behaviors across varied systems. This review systematically integrates fundamental electrochemical mechanisms, reaction kinetics identifications, and device application insights, establishing a comprehensive framework ...
Meng Zhang, Jiguo Tu, R. Vasant Kumar, Libo Chen, Tangkai Wu, Lili Jiang, Shuqiang Jiao   +6 more
wiley   +1 more source

Investigations into effects of 12-lipoxygenase and NADPH oxidase on platelet activity, and influences of dietary dark chocolate

, 2012
PhDPlatelets play a pivotal role in both normal hemostasis and pathological bleeding and importantly also contribute to the development of atherothrombosis.
Zain, Zetty Nadia Mohd
core  

Commonalities of platelet dysfunction in heart failure with preserved ejection fraction and underlying comorbidities

ESC Heart Failure, Volume 12, Issue 2, Page 1013-1028, April 2025.
Abstract Heart failure with preserved ejection fraction (HFpEF) is characterized by a lack of a specific targeted treatment and a complex, partially unexplored pathophysiology. Common comorbidities associated with HFpEF are hypertension, atrial fibrillation, obesity and diabetes.
Giorgia D'Italia, Blanche Schroen, Judith M.E.M. Cosemans   +2 more
wiley   +1 more source

Photothermal preconditioning of platelet-rich plasma: An emerging regenerative strategy. [PDF]

Regen Ther
Sánchez-Vizcaíno Mengual E, Cordero L, Pinto H.   +2 more
europepmc   +1 more source

Discussing the Debate: Leukocyte-Rich Platelet-Rich Plasma Versus Leukocyte-Poor Platelet-Rich Plasma

Cureus
This editorial touches on the persistent debate related to platelet-rich plasma (PRP) therapy. It focuses on the different approaches involving leukocyte-rich and leukocyte-poor PRP formulations of the PRP. It looks into the reasons behind these approaches, their potential effects on clinical practice, i.e., pros and cons, and the evidence supporting ...
openaire   +2 more sources

The effects of injecting intra-articular platelet-rich plasma or prolotherapy on pain score and function in knee osteoarthritis

, 2018
Poupak Rahimzadeh,1 Farnad Imani,1 Seyed Hamid Reza Faiz,2 Saeed Reza Entezary,3 Mahnaz Narimani Zamanabadi,4 Mahmoud Reza Alebouyeh3 1Pain Research Center, Iran University of Medical Sciences, Tehran, Iran; 2Endometriosis Research Center, Iran ...
Alebouyeh MR, Rahimzadeh P, Zamanabadi MN, Faiz SHR, Imani F, Entezary SR   +5 more
core  

Clinical and research applications of synthetic bone substitutes in equine veterinary medicine: A systematic review

Equine Veterinary Journal, EarlyView.
Abstract Background Bone grafting in equine medicine offers a promising contribution to treating orthopaedic developmental diseases and chondral, osteochondral and segmental bone defects. Among grafts, synthetic bone substitutes—alloplastics—show favourable biological properties addressing numerous limitations presented by autografts, xenografts and ...
Katarzyna Skierbiszewska, Bernard Turek, Tomasz Jasiński, Michał Kaczorowski, Natalia Kozłowska, Julia Higuchi, Małgorzata Domino   +6 more
wiley   +1 more source