Results 61 to 70 of about 2,803,684 (283)

Pre‐Regenerative Endothelial Cells Empowered by Antler Blood Exosomes Orchestrate Peripheral Nerve Repair

Advanced Science, EarlyView.
The pre‐regenerative vascular niche (PVN) is essential for nerve repair, yet its endothelial blueprint remains unclear. We identified angiogenic ECs (AECs) as the dominant pre‐regenerative subset and found that antler blood–derived exosomes (AB‐EXO) promote repair via IMP3.
Jinsheng Huang, Qiang Chen, Aihua Jin, Xiaoqi Yang, Hui Zhou, Weiquan Gong, Jin Cheng, Jun Dai, Minjin Wang, Meihua Piao, Yuanyi Wang, Nan Zhou   +11 more
wiley   +1 more source

Ozone-activated platelet-rich plasma combined with occlusal splint therapy in the treatment of temporomandibular joint osteoarthritis [PDF]

Revista Portuguesa de Estomatologia, Medicina Dentária e Cirurgia Maxilofacial
Objectives: To evaluate the efficacy of intra-articular infiltration of ozone-activated platelet-rich plasma combined with occlusal splint therapy in the treatment of patients with temporomandibular joint osteoarthritis.
Reynier Ramírez, Yoan R. Arango
doaj   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

Platelet-rich plasma (PRP) a biogenic stimulator in treatment of primary atrophic rhinitis

The Egyptian Journal of Otolaryngology, 2020
Background Primary atrophic rhinitis (1ry AR) is a chronic nasal disease characterized by the loss of mucociliary clearance and presence of viscid secretions and dried crusts that causes a characteristic foul odor, usually bilateral.
Hany Samir Mostafa, Essam Ezzat Ayad
doaj   +1 more source

Engineered Au@CeO2 Hybrid Nanoparticles With Microenvironment Dependent Self‐Adjustability for Integration of Tumor‐Specific Photothermal‐Chemodynamic Therapy and Inflammation Prevention

Advanced Science, EarlyView.
An intelligent Au@CeO2 Hybrid Nanoparticles (ACEF) with microenvironment‐dependent self‐adjustability was engineered to not only perform efficient and tumor‐specific photothermal‐chemodynamic therapy for precise tumor elimination, but also serve as a ROS scavenger in healthy tissues around the tumor to avoid the unexpected oxidative damage and ...
Wenyun Mu, Wenjuan Tang, Handan Zhang, Jie Liu, Jiaqi Zhang, Yu Yao, Xiao Fu, Xin Chen, Yanmin Zhang   +8 more
wiley   +1 more source

Platelet-Rich Plasma in Wound Treatment

Przegląd Dermatologiczny
Platelet-rich plasma is a widely used autologous preparation applied in the treatment of various medical conditions. To date, it has been used in several fields of medicine, including orthopedics, regenerative medicine, aesthetic medicine, and the ...
Alicja Ziętara, Kacper Grabowski, Oliwia Maciaszek, Natalia Chwarścianek, Rafał Czajkowski   +4 more
doaj   +1 more source

Investigations into Centrifugal Separations for Preparation of Platelet Rich Plasma (PRP) [PDF]

, 2004
P(論文)Platelet rich plasma (PRP) has beneficial effects on wound healing and bone regeneration. Therefore, PRP is applied in various clinical treatments hereafter, for example, in oral implants and in bone grafts.
8695, 8696, 8694, 8699, 8710, ハマダ, トモヒロ, 8711, 8697, SHIBATA, Yumiko, 8698, 大野, 敬, 金, 秀樹, 高田, 訓, HAYASHI, Yuki, KON, Hideki, 園田, 正人, シバタ, ユミコ, HAMADA, Tomohiro, 8709, コン, ヒデキ, ハヤシ, ユウキ, 8703, 8704, 8701, 浜田, 智弘, 8702, 8707, 8708, 8705, 8706, SONODA, Masahito, 8700, オオノ, タカシ, OHNO, Takashi, TAKADA, Satoshi, 柴田, 由美子, ソノダ, マサヒト, 8714, 林, 由季, 8712, タカダ, サトシ, 8713   +41 more
core  

CD31+ Cell Enrichment Enhances Therapeutic Effects of Stromal Vascular Fraction in Experimental Primary Osteoarthritis: A Preclinical Study in the Dunkin Hartley Guinea Pig Model

Advanced Science, EarlyView.
Both SVF and CD31+ SVF improve spontaneous osteoarthritis, but CD31+ enrichment refines the therapeutic profile rather than broadly enhancing all effects. More distinct benefits are observed in extracellular matrix remodeling, osteochondral integrity, and subchondral/trabecular bone preservation, supporting CD31+‐enriched SVF as a biologically enhanced
Sijia Zhou, Tobias Winkler, Bin Chen, Marta Grzeski, Yilong Yang, Florian N. Fleckenstein, Dominik Geisel, Alexander Hildebrandt, Daniela Aschenbrenner, Marie Agatha Mohn, Benjamin Claass, January Weiner 3rd, Sven Geissler, Georg N. Duda, Søren P. Sheikh, Oliver Klein, Tazio Maleitzke   +16 more
wiley   +1 more source

Genetic Ablation and Multi‐Omics Profiling Reveal CEP55 as a Key Driver of Tumorigenesis in Diverse Cancer Models

Advanced Science, EarlyView.
Genetic ablation of Cep55 in Pten‐deficient mouse models delays tumorigenesis. Integrated multi‐omics analyses (proteomics, phosphoproteomics, and spatial transcriptomics) reveal that CEP55 regulates oncogenic signaling (RAS/ERK, PI3K/AKT), integrin/FAK‐mediated adhesion, extracellular matrix (ECM) remodeling, and endocytosis.
Behnam Rashidieh, Yuanhao Yang, Amanda Louise Bain, Phillip Theron, Catharina Vosloo, Sahar Keshvari, Parinaz Ahangar, Brydie Bowden, Simon M. Tria, Ben B. Wang, Sandra Isenmann, Nicholas J. Westra van Holthe, Zherui Xiong, Hani Vu, Sowmya Sharma, Asmerom Sengal, J. Alejandro Lopez, John Finnie, Antonella Papa, Pascal H.G. Duijf, Quan Nguyen, Pirjo M. Apaja, Kum Kum Khanna   +22 more
wiley   +1 more source

Inadequate anticoagulation and hyperuricemia cause knee pain after platelet-rich plasma injection: A retrospective study

Journal of Orthopaedic Surgery
Objectives Platelet-rich plasma treatment delays the need for total knee replacement in patients with knee osteoarthritis. However, its use and preparation remain controversial.
Yang Chen, Hongxun Sang, Song Wu, Haobin Zhang, Yi Zhang, Hongxing Li   +5 more
doaj   +1 more source