Results 171 to 180 of about 91,077,287 (299)

Hematological and Genotoxic Effects of Subchronic Oral Exposure to a Mancozeb‐Based Fungicide in Female Mice

Journal of Applied Toxicology, EarlyView.
ABSTRACT The extensive use of pesticides in modern agriculture has raised increasing concerns regarding the potential biological effects of repeated exposure to pesticide residues and commercial formulations. Mancozeb is a widely used ethylene‐bis‐dithiocarbamate fungicide; however, information on its hematological and genotoxic effects following ...
Matheus Henrique Barcelos Figueiredo, Natanael Vaz Crisóstomo Peixoto, Paula Soares Nakamura, Cecília Müller Wodzik, Lucas Ribeiro Maia dos Santos, Fábio Vieira de Andrade Borges, Lara Cândida de Sousa Machado, Jéssica Gardone Vitório, Renata Mazaro e Costa, Mônica Rodrigues Ferreira Machado, Walter Dias Júnior   +10 more
wiley   +1 more source

Standardization of the Monocyte Monolayer Assay: Lessons Learned From Laboratory Optimization and Literature Review

Journal of Clinical Laboratory Analysis, EarlyView.
Standardization of monocyte monolayer assay in a developing country. This study highlights the significance of literature review and adopting best techniques for standardization of a new procedure at individual center before implementing into practice. ABSTRACT Objectives Several variables influence the outcome of cellular assays.
Shamee Shastry, Kavya Babu, Deepika Chenna, Ganesh Mohan, Kartik Iyer   +4 more
wiley   +1 more source

Interleukin‐37 Enhances Liver NK Cell Cytotoxicity and Improves Recurrence‐Free Survival in Hepatocellular Carcinoma Patients

Journal of Hepato-Biliary-Pancreatic Sciences, EarlyView.
ABSTRACT Introduction Hepatocellular carcinoma (HCC) remains a major cause of cancer‐related mortality worldwide, and postoperative recurrence continues to limit long‐term survival. Liver‐resident natural killer (NK) cells are key effectors of antitumor immunity in the hepatic microenvironment. Interleukin‐37 (IL‐37), an anti‐inflammatory cytokine, has
Yuki Imaoka, Masahiro Ohira, Yuka Tanaka, Toshihiro Nakayama, Miho Akabane, Shinichiro Yokota, Sheri M. Krams, Olivia M. Martinez, Carlos O. Esquivel, Kazunari Sasaki, Hideki Ohdan   +10 more
wiley   +1 more source

Dual biologic therapy in inflammatory bowel disease, a retrospective cohort study of vedolizumab and anti‐tumor necrosis factor alpha therapy in children

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives Despite advances in pediatric inflammatory bowel disease (PIBD) with biologics, remission rates remain at 47%–60% with loss‐of‐response rates at 60%–68%. Evidence for efficacy of dual biologic therapy (DBT) with anti‐tumor necrosis factor alpha therapy (anti‐TNF‐α)‐ vedolizumab (VDZ) for children refractory to anti‐TNF‐α therapy is ...
Jonathan E. M. O'Donnell, Carlie Bolles, Claire R. Reilly, Manal Morgan, Christopher Burgess, Fariha Balouch, Peter J. Lewindon   +6 more
wiley   +1 more source

Diffuse gastrointestinal hemorrhage associated with emapalumab treatment of macrophage activation syndrome: A case report

JPGN Reports, EarlyView.
Abstract Macrophage activation syndrome (MAS) is a complex hyperinflammatory syndrome and continues to have evolving treatment options. This case discusses a 19‐month‐old with MAS associated liver failure and multiorgan dysfunction. Her course was complicated by gastrointestinal (GI) bleed.
Samuel E. Hagman, Cary P. Cavender, David S. Willcutts   +2 more
wiley   +1 more source

Gastroprotective effects of Sapodilla fruit powder against ethanol‐induced gastric injury in Sprague–Dawley rats: In silico prediction and in vivo validation

JSFA reports, EarlyView.
Abstract Background Gastrointestinal disorders are rapidly increasing worldwide due to the disturbance of mucosal defenses. Manilkara zapota possesses significant therapeutic attributes to improve individual well‐being. Objectives The current study was conducted to evaluate the antioxidant activity, phytochemical characterization, and in silico and in ...
Ayesha Siddiqa, Adnan Amjad, Muhammad Maaz, Ahmad Mujtaba Noman, Tadesse Fenta Yehuala, Shehnshah Zafar, Syeda Khimar Zahra Kazmi, Duaa Tariq   +7 more
wiley   +1 more source

Prognostic Determinants of Overall Survival After Resection for Pancreatic Ductal Adenocarcinoma: A Consensus‐Based Conceptual Framework

Journal of Surgical Oncology, EarlyView.
ABSTRACT Pancreatic ductal adenocarcinoma (PDAC) carries a dismal prognosis despite surgical resection, yet the prognostic literature remains fragmented across hundreds of single‐institution studies that vary in design, covariates, and analytical approaches.
Muhammad Maisam Ali, Kaleem S. Ahmed, Clayton T. Marcinak, Syed Ali Tayyeb Hasan, Anne D. Letocha, Noorain Ahmad, Haider bin Khalid, Kainat Fatima, Syed Nabeel Zafar   +8 more
wiley   +1 more source

Platelet-to-lymphocyte ratio as an indicator of idiopathic epilepsy in dogs. [PDF]

J Vet Intern Med
Wang J, Chae Y, Koo Y, Yun T, Kim H, Kang BT.   +5 more
europepmc   +1 more source

Value of the Platelet-to-Lymphocyte Ratio and Platelet-to-Lymphocyte Product in the Evaluation of Systemic Lupus Erythematosus Disease Activity. [PDF]

J Inflamm Res
Li S, Yan M, Lu J, Liu Z, Xue L.
europepmc   +1 more source

Development and External Validation of a Postoperative Risk Score for Venous Thromboembolism in Epithelial Ovarian Cancer

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Venous thromboembolism (VTE), including deep vein thrombosis and pulmonary embolism, is a major complication in women with epithelial ovarian cancer (EOC). We aimed to develop and externally validate an early postoperative risk score to identify EOC patients at increased risk of VTE after debulking surgery.
Qiu‐Lin Cui, Yu‐Shi He, Xuan‐Hui Wang, Cheng Li, Gang Wang, Ming Chen, Shu‐Min Chen   +6 more
wiley   +1 more source