Platelet-to-lymphocyte ratio and mean platelet volume in recurrent aphthous stomatitis: Systematic review and meta-analysis of group differences. [PDF]
Aborisade A +7 more
europepmc +1 more source
Gene expression signatures from single‐cell transcriptomics predict Sjögren's syndrome
A machine learning‐based 12‐gene signature (SjS.Sig) was developed from scRNA‐seq data of PBMCs from Sjögren's syndrome patients. The model was validated using bulk RNA‐seq datasets and further confirmed through flow cytometry and qPCR analysis in an independent clinical cohort, demonstrating robust diagnostic potential.
Shumin Cheng +20 more
wiley +1 more source
Association between platelet to lymphocyte ratio and the risk of vertebral fracture in patients with osteoporosis: a systematic review and meta-analysis. [PDF]
Hu F, Zhan Y, Yao J, Cheng M, Wang J.
europepmc +1 more source
The gut microbiome can be conceptualized as a distributed organ‐like functional system with spatially structured organization, broad biochemical capacity, and continuous bidirectional communication with the host. By transforming dietary, host‐derived, and environmental substrates into bioactive metabolites with endocrine‐like, immunomodulatory, and ...
Yang Bi +22 more
wiley +1 more source
The predictive value of platelet-to-lymphocyte ratio and lymphocyte count in recurrent small intestinal hemorrhage: a retrospective cohort study. [PDF]
Han L, Jin Y, Liu Z, Zeng C, Chen Y.
europepmc +1 more source
The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li +29 more
wiley +1 more source
Interaction effects of testosterone and platelet-to-lymphocyte ratio on osteoporosis in U.S. adults: Insights from the NHANES 2011 to 2016 cohort. [PDF]
Tao C, Liu Y, Shen H, Li T, He Y.
europepmc +1 more source
ABSTRACT Insulin resistance is the biological phenomenon in which the human body's normal response to the metabolic hormone insulin is compromised. Insulin is a regulator of most of the essential metabolic steps in the body that control energy homoeostasis, so dysregulation leads to multiple diverse human diseases including, most prominently, Type 2 ...
Peter J. Little +12 more
wiley +1 more source
Improved prediction value of the CURB-65 score combined with the platelet-to-lymphocyte ratio for mortality in emergency department patients with severe community-acquired pneumonia. [PDF]
Lv C, Liu S, Yan Y, Ye Y, Gao Y, Zhou M.
europepmc +1 more source

