Results 141 to 150 of about 91,077,287 (299)

Tackling cancer stemness with nanotechnology in the era of precision medicine

BMEMat, EarlyView.
Precise customization of nanoparticles (NPs) enables active targeting of cancer stem cells (CSCs), thereby improving drug delivery and therapeutic efficacy. NP‐based probing enhances CSC detection through imaging and liquid biopsy, whereas diverse therapeutic payloads improve therapeutic outcomes.
Shaolei Guo, Shun Yao, Lihui Meng, Chunyuan Chen, Yuechu Lucinda Lu, Rong Lu, Kashif Rafiq Zahid, Umar Raza, Qingzhi Wu, Wenli Chen   +9 more
wiley   +1 more source

Glycosylated dendrimer nanoamplifiers hijack DNA damage‐immune crosstalk for enhanced dual‐track therapy of orthotopic glioblastoma

BMEMat, EarlyView.
A glycosylated dendrimer nanoamplifier hijacks DNA damage‐immune crosstalk for enhanced radio‐immunotherapy of glioblastoma. The responsive release of demethylcantharidin simultaneously blocks repair‐mediated resistance by inhibiting DNA repair and overcomes adaptive immune resistance.
Cong Song, Binghan Liu, Junjie Liu, Ce Li, Wenqing Man, Xurui Sun, Chang Yuan, Yanjun Wang, Hong Pan, Shuanglian Wang, Zhiming Zheng   +10 more
wiley   +1 more source

Application Value of Platelet-to-Lymphocyte Ratio as a Novel Indicator in Rheumatoid Arthritis: A Review Based on Clinical Evidence [PDF]

Shengfeng Liu,1,2 Jian Liu,1,2 Xueni Cheng,1 Dahai Fang,1 Xiaolu Chen,1 Xiang Ding,1 Xianheng Zhang,1 Yiming Chen1 1Department of Rheumatology, the First Affiliated Hospital of Anhui University of Chinese Medicine, Hefei, Anhui Province, People’s ...
Liu J, Ding X, Fang D, Zhang X, Chen Y, Liu S, Chen X, Cheng X   +7 more
core  

Overall survival curves in low and high platelet-to-lymphocyte ratio patients.

, 2016
The difference between groups were statistically significant (log-rank test, P = 0.030). PLR, platelet-to-lymphocyte ratio; NLR, neutrophil-to-lymphocyte ratio.
Xuehua Yao (2216329), Yu Wang (12152), Jiaping Li (119498), Yingqiang Zhang (2216326), Jianyong Yang (2216335), Wenzhe Fan (2216332)   +5 more
core   +1 more source

Bacterial backpacks for targeted delivery of piezoelectric nanoparticles to enhance sonodynamic immunotherapy

BMEMat, EarlyView.
Leveraging bacterial hypoxia targeting, KBTO NPs accumulate at the tumor site. Under the ultrasound irradiation, KBTO NPs produce reactive oxygen species to kill tumor cells and eliminate bacteria, preventing overgrowth and inflammation. The lysed bacteria act as antigens to trigger antitumor immunity and further enhanced by the immune checkpoint ...
Chongyang Liu, Haohui Zhu, Huaibin Yu, Xijun Zhang, Zhiqin Lei, Wenjing Xu, Xinyu Zhao, Ming Wu, Long Yang, Juanjuan Liu, Zhengbao Zha, Xinghui Si, Jianjun Yuan   +12 more
wiley   +1 more source

Nanomedicine‐driven innovations in postoperative cancer immunotherapy: Remodeling tumor microenvironment and precision delivery strategies

BMEMat, EarlyView.
Nanomedicine‐Driven Strategies for Suppressing Postoperative Tumor Recurrence. This schematic illustrates three pivotal nanomedical strategies that synergistically counteract recurrence by targeting residual disease and the immunosuppressive tumor microenvironment within the surgical cavity.
Lisong Pang, Zhuomin Wang, Zhenhua Jin, Ahmed H. Ghonaim, Hengcheng Zhang, Xinyu You, Jinzhuo Ning, Jiaqing Cao, Yang Liu   +8 more
wiley   +1 more source

Prognostic Value of Neutrophil-To-Lymphocyte Ratio and Platelet-To-Lymphocyte Ratio for Renal Outcomes in Patients with Rapidly Progressive Glomerulonephritis [PDF]

Background: Rapidly progressive glomerulonephritis (RPGN) is a syndrome characterized by a rapid decline in renal function that often causes end-stage renal disease.
Fukuda, Satoko, Isomoto, Hajime, Iyama, Takuji, 26896, 福田, 佐登子, 26895, Taniguchi, Sousuke, 1082, 396, 26890, Ida, Ayami, 26892, 26891, 90322304, 26894, 26893, タカタ, トモアキ, フクダ, サトコ, 磯本, 一, 3618, タニグチ, ソウスケ, 100001163, イソモト, ハジメ, 高田, 知朗, 100001541, Yamamoto, Marie, Mae, Yukari, 100000933, Takata, Tomoaki, Ogawa, Masaya   +29 more
core   +1 more source

Innovation of plant‐derived extracellular vesicles and interdisciplinary research: From discovery to biomedical applications

BMEMat, EarlyView.
Plant‐derived extracellular vesicles offer numerous advantages and are regarded as highly promising candidates in the field of biomedicine. Abstract Extracellular vesicles (EVs) are double‐membrane vesicular structures that can be secreted by nearly all living cells.
Zilin Li, Yi Wei, Ben Hu, Yafang Song, Xiaojia Chen, Nik Ahmad Nizam Nik Malek, Tongkai Chen   +6 more
wiley   +1 more source

Prognostic Value of the Neutrophil-to-lymphocyte Ratio, Platelet-to- lymphocyte Ratio and Monocyte-to-lymphocyte Ratio in Melanoma Patients: A Cohort Study

The prognostic value of the neutrophil-lymphocyte ratio, platelet-lymphocyte ratio and monocyte-lymphocyte ratio in patients with melanoma has yielded controversial results in the literature.
Cristina Carrera, Cristina Mangas, Sebastian Podlipnik, Susana Puig, Josep Malvehy, Constanza Riquelme-Mc Loughlin, Sümeyre Seda Ertekin   +6 more
core   +1 more source

Engineered immunostimulatory H2O2‐producing microreactors driven by yeast as localized living cancer therapeutics

BMEMat, EarlyView.
Engineered yeast microreactors that produce H2O2 within tumors enable selective cancer cell killing while releasing immunostimulatory components, effectively suppressing local tumor growth and activating systemic antitumor immunity, with further efficacy enhanced by anti‐PD‐1 therapy and transarterial embolization.
Wenqian He, Chunjie Wang, Minming Chen, Weihao Yang, Bin Yu, Yuhang Hu, Hengze Ding, Yifan Yan, Zhijuan Yang, Liangzhu Feng   +9 more
wiley   +1 more source