Results 131 to 140 of about 91,077,287 (299)

A Novel Bioactive Component, Efoba, From Aged Garlic Targets CTSC to Suppress NET‐Driven Neuroinflammation and Ameliorate Secondary Brain Injury After Intracerebral Hemorrhage

Advanced Science, EarlyView.
Efoba, a novel bioactive component derived from aged garlic, confers neuroprotection against intracerebral hemorrhage. It acts on microglia to suppress CTSC release, inhibits NET‐mediated neural injury, and blocks pathological microglia‐neutrophil crosstalk. This study provides a highly promising lead compound for hemorrhagic‐stroke therapy.
Junjun Meng, Jianhua Wang, Tao Zhang, Xiaofan Fan, Jinxiu Guo, Shiyuan Zhao, Wenxue Sun, Pei Jiang   +7 more
wiley   +1 more source

Prognostic Significance and Clinical Robustness of the HALP Score in Super‐Elderly Patients Undergoing Curative Gastrectomy for Gastric Cancer: A Multicenter Retrospective Cohort Study

Annals of Gastroenterological Surgery, EarlyView.
In this multicenter study of 507 patients aged ≥ 80 years who underwent curative gastrectomy for gastric cancer, a low preoperative HALP score was independently associated with poor overall survival. This association remained consistent across multiple complementary analyses, and low HALP was also associated with both cancer‐specific and other‐cause ...
Hiroyuki Inoue, Takeshi Kubota, Toshiyuki Kosuga, Keiji Nishibeppu, Shutaro Sumiyoshi, Junichi Hamada, Kazuya Takabatake, Keita Katsurahara, Yosuke Ariyoshi, Koji Miyagawa, Sojin Sai, Yoshiki Itokawa, Tomoya Hatakeyama, Fumiaki Ochi, Hirotaka Konishi, Hitoshi Fujiwara, Atsushi Shiozaki   +16 more
wiley   +1 more source

Association between baseline clinical and angiographic characteristics and outcomes of the study population and neutrophil-to-lymphocyte ratio (NLR) or platelet-to-lymphocyte ratio (PLR).

, 2015
NLR neutrophil to lymphocyte ratio, PLR platelet to lymphocyte ratio, eGFR estimated glomerular filtration rate according to the Modification of Diet in Renal Disease (MDRD) equation, hs-CRP high sensitivity C-reactive protein, DES drug eluting stent, MI
Ae-Young Her (775370), Soe Hee Ann (775368), Kyoung Im Cho (775367), Gillian Balbir Singh (775369), Eun-Seok Shin (775371)   +4 more
core   +1 more source

Association of urinary neopterin, neutrophil-to-lymphocyte, lymphocyte-to-monocyte and platelet-to-lymphocyte ratios with long-term survival of patients with breast cancer

Pteridines, 2016
The immune response crucially determines the survival of patients with malignant tumors including breast carcinoma. The aim of the present study was to evaluate retrospectively an association of peripheral blood cell count (PBC)-derived ratios and ...
Melichar Bohuslav, Študentová Hana, Vitásková Denisa, Šrámek Vlastislav, Kujovská Krčmová Lenka, Pešková Eliška, Solichová Dagmar, Kalábová Hana, Ryška Aleš, Hrůzová Klára, Havlík Roman   +10 more
doaj   +1 more source

Plasma Proteome Reflects Tissue Damage and Clinical Manifestations in Patients With Inflammatory Myopathies

Arthritis &Rheumatology, EarlyView.
Objective Tissue‐specific biomarkers that are reliable and associated with clinical manifestations of idiopathic inflammatory myopathy (IIM) are lacking. The blood circulation in individuals serves as a central conduit, allowing communication between tissues and facilitating clearance and recycling of tissue‐derived proteins.
Yue‐Bei Luo, Josefin Kenrick, Angeles S. Galindo‐Feria, Antonella Notarnicola, Ana Daniela Ulloa Navas, Irene Peralta‐Garcia, Orane Demuynck, Andrea Kemp, Valérie Leclair, Karin Lodin, Eveline Van Gompel, Lara Dani, Fabricio Espinosa‐Ortega, Maryam Dastmalchi, Leonid Padyukov, Charlotta Preger, María Bueno Álvez, Mathias Uhlén, Peter Nilsson, Fredrik Edfors, Lina‐Marcela Diaz‐Gallo, Elisa Pin, Ingrid E. Lundberg, Begum Horuluoglu   +23 more
wiley   +1 more source

Platelet-to-Lymphocyte Ratio (PLR), Neutrophil-to-Lymphocyte Ratio (NLR), Monocyte-to-Lymphocyte Ratio (MLR), and Eosinophil-to-Lymphocyte Ratio (ELR) as Biomarkers in Patients with Acute Exacerbation of Chronic Obstructive Pulmonary Disease (AECOPD)

International Journal of COPD
Qian-Qian Liao,1,* Yan-Ju Mo,2,* Ke-Wei Zhu,3,4,* Feng Gao,2 Bin Huang,2 Peng Chen,4 Feng-Tian Jing,5 Xuan Jiang,6 Hong-Zhen Xu,1 Yan-Feng Tang,7 Li-Wei Chu,8 Hai-Ling Huang,1 Wen-Li Wang,8 Fang-Ning Wei,9 Dan-Dan Huang,9 Bin-Jing Zhao,9 Jia ...
Liao QQ, Mo YJ, Zhu KW, Gao F, Huang B, Chen P, Jing FT, Jiang X, Xu HZ, Tang YF, Chu LW, Huang HL, Wang WL, Wei FN, Huang DD, Zhao BJ, Chen J, Zhang H   +17 more
doaj  

Use of Mean Platelet Volume and Neutrophil-To-Lymphocyte Ratio as Predictors of Postoperative Transfusion Needs and Morbidity in Total Knee and Hip Arthroplasties

Objective: This study aimed to evaluate the diagnostic value of the neutrophil-to-lymphocyte ratio (NLR) as a predictor of postoperative blood transfusion requirements, intensive care unit (ICU) admission, and prolonged hospital stay in patients ...
Cumhur Deniz Davulcu, Ece Davutluoğlu, davulcu, cumhur deniz, DAVUTLUOGLU, ECE   +3 more
core   +1 more source

Neurovascular coupling in bone regeneration: Mechanisms, advanced biomaterials and challenges

BMEMat, EarlyView.
This figure illustrates various material strategies for neurovascularized bone regeneration, including electroactive scaffolds, ion‐loaded materials, drug delivery systems, surface modifications, cells/cell products, growth factors, and peptides. These approaches aim to synergistically promote the regeneration of neural, vascular, and bone tissues ...
Yixin Ma, Nan Jiang, Liyuan Chen, He Zhang, Xinjia Cai, Karan Gulati, Danqing He, Zhigang Cai, Yan Liu   +8 more
wiley   +1 more source

Assessment of neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio, and mean platelet volume in patients with diabetic retinopathy

Journal of Clinical Ophthalmology and Research
Objective: The objective of this study was to assess the role of inflammation in the pathogenesis of diabetic retinopathy (DR) using the neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), and mean platelet volume (MPV) and to ...
Trisha Ghosh, Sanjay Kumar Daulat Thakur, Premangshu Ghosh, Trina Sengupta   +3 more
doaj   +1 more source

Total lymphocyte count, neutrophil–lymphocyte ratio, and platelet–lymphocyte ratio as prognostic factors in advanced non–small cell lung cancer with chemoradiotherapy

, 2018
Xinyu Song,1,2,* Dawei Chen,3,* Ma Yuan,4 Haiyong Wang,1 Zhehai Wang1 1Department of Medical Oncology, Shandong Cancer Hospital Affiliated to Shandong University, Jinan, Shandong, China; 2School of Medicine and Life Sciences, University of Jinan-Shandong
Yuan M, Wang H, Song X, Wang Z, Chen D
core