Results 141 to 150 of about 84,496 (265)

Anti‐HPA‐1a IgG3 subclass antibodies induce strong platelet phagocytosis

British Journal of Haematology, EarlyView.
Silke Schmidt, Xiuzhang Xu, Gabriela Michel, Hartmut Kroll, Gregor Bein, Sentot Santoso   +5 more
wiley   +1 more source

Post‐Transplant Bendamustine as a Platform for Immune Modulation After Allogeneic Hematopoietic Cell Transplantation

European Journal of Haematology, EarlyView.
ABSTRACT Post‐transplant cyclophosphamide (PT‐CY) remains the standard of care for graft‐versus‐host disease (GvHD) prophylaxis in haploidentical hematopoietic cell transplantation (HCT), yet relapse, delayed immune reconstitution, infections, and organ toxicity represent persistent and clinically meaningful limitations.
Megan J. Cracchiolo, Richard J. Simpson, Emmanuel Katsanis   +2 more
wiley   +1 more source

Platelet desialylation, apoptosis, and T-lymphocyte-mediated immune dysregulation: unveiling the pathways of platelet clearance in platelet transfusion refractoriness. [PDF]

Res Pract Thromb Haemost
Zhou Y, Zhong Z, Mo H, Liang L, Su C, Chen Y, Lu F, Huang Y, Wu G.   +8 more
europepmc   +1 more source

Third Allogeneic Stem Cell Transplantation in Children: A Multicenter Analysis From the Spanish GETH‐TC Pediatric Group

European Journal of Haematology, EarlyView.
ABSTRACT Third allogeneic hematopoietic stem cell transplantation (HSCT3) is rarely performed in pediatric patients and is associated with high toxicity and mortality. Data on outcomes in this setting remain scarce. We conducted a retrospective multicenter study within the Spanish GETH‐TC Pediatric group including 29 children and adolescents who ...
Luisa Sisinni, Sara Vinagre Enríquez, Marta Villalon Herrera, Mercedes Plaza Fornieles, Iván López Torija, Andrea Urtasun Erburu, Laura Alonso García, Alexandra Regueiro García, Maria Trabazo del Castillo, Eduardo J. Bardón‐Cancho, Odelaisy León‐Triana, Carla Miñarro Chacón, José Luís Fuster Soler, Antonio Pérez‐Martínez, Pascual Balsalobre López, Marta Gonzalez‐Vicent, Cristina Díaz de Heredia, on behalf of the GETH‐TC Pediatric Working Group   +17 more
wiley   +1 more source

Platelet Transfusion Thresholds for Children Supported by Extracorporeal Membrane Oxygenation: The Extracorporeal Membrane Oxygenation Hemostatic Transfusions in Children (ECSTATIC) Feasibility Clinical Trial. [PDF]

Crit Care Med
Nellis ME, Barney BJ, Coles G, Cholette JM, Choudhury TA, Furlong-Dillard J, Ozment C, Bain J, Niebler RA, Chegondi M, Badheka A, Schiller O, Shostak E, Joashi U, Paden M, Alvey JS, Muszynski JA, Spinella PC, Tucci M, Lacroix J, Stanworth S, O'Neil ER, Pollak U, Bahr T, Kumar SR, Karam O, BloodNet and PediECMO, subgroups of the Pediatric Acute Lung Injury and Sepsis Investigators (PALISI).   +27 more
europepmc   +1 more source

Longitudinal Changes in Transfusion Practice in Myelodysplastic Syndromes: A Population Data‐Linkage Study

European Journal of Haematology, EarlyView.
ABSTRACT Background Real‐world data on transfusion needs of patients with myelodysplastic syndromes (MDS), and the impacts of disease‐modifying therapies (DMTs) are sparse. In 2011, 5‐azacitidine became the first funded DMT for MDS and chronic myelomonocytic leukaemia (CMML) patients in Australia and national patient blood management (PBM) guidelines ...
Allison Mo, Le Thi Phuong Thao, Cameron Wellard, Erica M. Wood, Jake Shortt, Zoe K. McQuilten   +5 more
wiley   +1 more source

Effect of prophylactic platelet transfusion on bleeding risk in patients with cirrhosis and thrombocytopenia undergoing ultrasound-guided liver biopsy. [PDF]

Ultrasonography
Jang HJ, Park HJ, Choi J, Heo S, Choi SJ, Kim SY, Lee SS.   +6 more
europepmc   +1 more source

Rare Bleeding Disorders and Bleeding Disorder of Unknown Cause: Current Understanding and Recent Developments

Haemophilia, EarlyView.
ABSTRACT Rare bleeding disorders (RBDs) represent a diverse group of inherited conditions involving coagulation factors or platelets. These conditions, such as Glanzmann thrombasthenia (GT) or severe coagulation factor deficiencies, are uncommon. In contrast, bleeding disorder of unknown cause (BDUC) is a diagnosis of exclusion without an identifiable ...
Alessandro Casini, Robert Klamroth, Bauke Haisma, Dino Mehic, Saskia E. M. Schols   +4 more
wiley   +1 more source

Platelet Transfusion Practices and Outcomes in Neonates and Children.

JAMA Netw Open
Goel R, Karam O, Warden DE, Birch RJ, Binns TC, Punzalan R, Roubinian N, Yurtsever N, Patel RM, Bougie D, Luban N, Josephson CD, Sola-Visner M, Nellis ME, NHLBI Recipient Epidemiology and Donor Evaluation Study-IV-Pediatric (REDS-IV-P).   +14 more
europepmc   +1 more source

An improvement project standardizing low prophylactic platelet transfusion dosing for infants. [PDF]

J Perinatol
Coletti K, Hershey JA, Devine M, Taft J, Schinella J, Ajiboye S, Gibbs K, Lambert MP, Friedman D, Thom CS.   +9 more
europepmc   +1 more source