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Platelet transfusion: Current challenges.
Transfusion Clinique et Biologique, 2018Since the late sixties, platelet concentrates are transfused to patients presenting with severe thrombocytopenia, platelet function defects, injuries, or undergoing surgery, to prevent the risk of bleeding or to treat actual hemorrhage. Current practices
C. Humbrecht, D. Kientz, C. Gachet
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Trigger for Platelet Transfusion
Vox Sanguinis, 2000Background and Objectives:The terms ‘platelet transfusion trigger’ are used in the scientific literature to indicate a value of the platelet count above which prophylactic platelet transfusion is usually not indicated. Most clinicians share the currently prevalent consensus published in several guidelines that a platelet transfusion trigger of 10,000 ...
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Clinics in Laboratory Medicine, 1996
Although platelet transfusion is a vital part of modern hemotherapy, many related issues are unresolved. The most appropriate trigger point of transfusion and the clinical utility of prophylactic transfusion are still debated, but the importance of patient-specific transfusion decisions is clear.
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Although platelet transfusion is a vital part of modern hemotherapy, many related issues are unresolved. The most appropriate trigger point of transfusion and the clinical utility of prophylactic transfusion are still debated, but the importance of patient-specific transfusion decisions is clear.
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Platelet Transfusions in Pediatrics
New England Journal of Medicine, 1957THE transfusion of fresh human platelets has been shown to be an effective and practical way to control the hemorrhagic episodes in thrombocytopenia.1 Recently a variety of technics have been devised for the preparation of platelet concentrates that permit prompt infusion of therapeutically effective amounts of platelets without the delay or ...
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Platelet dose for prophylactic platelet transfusions
Expert Review of Hematology, 2010Although guidelines exist to deal with some aspects of platelet transfusion practice, many important clinical issues have not been addressed in large randomized controlled trials (RCTs). Slichter et al. conducted a RCT of prophylactic platelet transfusions to determine the effects of the dose of platelets on clinical signs of bleeding, the use of ...
Joan, Cid, Miguel, Lozano
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Hematology/Oncology Clinics of North America, 1990
This article reviews appropriate platelet support of those patients who are chronically thrombocytopenic because of decreased platelet production, including those receiving chemotherapy or radiation treatments and those undergoing bone marrow transplants.
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This article reviews appropriate platelet support of those patients who are chronically thrombocytopenic because of decreased platelet production, including those receiving chemotherapy or radiation treatments and those undergoing bone marrow transplants.
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Status of Platelet Collection and Platelet Transfusion
Therapeutic Apheresis, 2001Abstract: Platelet product derived from single donor plateletpheresis is required to reduce the risks of adverse reactions by blood transfusion. The objectives of this study are to evaluate the status of platelet collection and its efficacy by various kinds of plateletpheresis equipment and to assess the achievement of platelet transfusion by platelet ...
S, Omokawa +9 more
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Refractoriness to platelet transfusion
Current Opinion in Hematology, 2002This review discusses the causes of refractoriness to platelet transfusions and presents three options for its management. Platelet refractoriness is a complication of platelet transfusion that affects variable proportions of patients, mostly depending on their diagnosis, previous immunologic stimuli, and type of blood products used for transfusion.
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JAMA: The Journal of the American Medical Association, 1965
The safety and hemostatic effects of platelet transfusions have been well demonstrated in a National Cancer Institute—Acute Leukemia Task Force supported collaborative study among five major institutions and the National Laboratories of the American Red Cross.
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The safety and hemostatic effects of platelet transfusions have been well demonstrated in a National Cancer Institute—Acute Leukemia Task Force supported collaborative study among five major institutions and the National Laboratories of the American Red Cross.
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Guidelines for Platelet Transfusion
JAMA: The Journal of the American Medical Association, 1988Thirty years ago platelet transfusions were not available. Thrombocytopenic bleeding led to morbidity and mortality in patients with aplastic anemia and hematologic malignancies. Now, platelet transfusions generally are as available as any physician wishes. This ready availability and the development of potent antibiotics have allowed hematologists and
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