Results 51 to 60 of about 372,643 (301)

Acute haemolytic reaction secondary to an ABO minor mismatched platelet transfusion from a group A blood donor

, 2019
Dear Sir, Platelet transfusion often requires non-ABO-compatible platelets due to high demand, specific requests (such as HLA matching or CMV negativity) and short shelf-life.
N. Crampton, Baidya, S, Crampton, N, Powley, T, Y. ‐W. Liew, T. Powley, Bryant, S, J. Daly, Jivan, Y, J. Morrison, Liew, Y-W, S. Bryant, Morrison, J, S. Baidya, Swain, F, Allen, A, A. Allen, Daly, J, Wilson, B, B. Wilson, F. Swain, Y. Jivan   +21 more
core   +1 more source

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa, Kyomi Kanaya, Kiyomi Aizawa, Masanori Onoki, Hirofumi Ozeki, Kazuko Suzuki, Ai Hayashi, Tomohiko Asamura   +7 more
wiley   +1 more source

Storage-induced change in platelet transfusion response evaluated by serial transfusions from one donor to one patient

, 2019
BACKGROUNDStorage of platelet concentrates (PCs) results in storage lesions with possible detrimental effects on platelet recovery after transfusion, which might affect their ability to prevent or arrest bleeding. The aim of this study was to compare the
Berlin, Gösta,, Tynngård, Nahreen,, Boknäs, Niklas,, Trinks, Marie,, Dreimane, Arta,   +4 more
core   +1 more source

Prophylactic platelet transfusions

Current Opinion in Hematology, 2010
This review highlights the recent research on the use of prophylactic platelet transfusions, which is a topic that still provokes controversy. Over the last 12 months, there have been several studies with important new findings.Two randomized controlled trials compared different doses of prophylactic platelet transfusions in patients with ...
Estcourt, L, Stanworth, S, Murphy, M
openaire   +3 more sources

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Characteristics and Outcomes of Liver Transplantation Recipients after Tranexamic Acid Treatment and Platelet Transfusion: A Retrospective Single-Centre Experience

Medicina, 2023
Background and Objectives: Patients undergoing liver transplantation (LT) often require increased blood product transfusion due to pre-existing coagulopathy and intraoperative fibrinolysis.
Mohmad H. Alsabani, Abdulrazak Sibai, Saja F. Alharbi, Lafi H. Olayan, Abeer A. Samman, Mohammed K. Al Harbi   +5 more
doaj   +1 more source

Platelet-leucocyte aggregation is augmented in cirrhosis and further increased by platelet transfusion [PDF]

, 2018
BACKGROUND: Thrombocytopenia and circulating dysfunctional immune cells are commonly observed in patients with cirrhosis. Platelets may form complexes with neutrophils, monocytes and T cells modulating their function.
Stoy, S., Lisman, T; id_orcid, Lisman, T., Bernal, W, J. P. Sturgeon, Støy, S, S. Støy, D. L. Shawcross, Sturgeon, J. P., V. C. Patel, Shawcross, D. L.; id_orcid, Manakkat Vijay, G K, Shawcross, D L, W. Bernal, T. Lisman, G. K. Manakkat Vijay, Vijay, G. K. Manakkat, Patel, V. C., Bernal, W., Sturgeon, J P, Patel, V C, Lisman, T   +21 more
core   +1 more source

Microfluidic Nano‐Assembly of Red‐Blood‐Cell (RBC) Lipids and Components for Engineering Extracellular Vesicles

Advanced Healthcare Materials, EarlyView.
Engineered red blood cell‐derived extracellular vesicles (eRBCEVs) are synthesized via controlled microfluidic assembly from native RBC lipids, enabling tunable encapsulation of proteins, nucleic acids, nanoparticles, and viral vectors. The platform demonstrates reproducible nanoscale architecture, preserved membrane composition, and functional cargo ...
Chiranth K. Nagaraj, Xilal Y. Rima, Kim T. Nguyen, Courtney Culkins, Nana Boateng, Jacob Doon‐Ralls, Alejandro Bresolin, Xin Huang, Hong Li, Vahedi Amid, Ajeet Pal Singh, Dharti Shantaram, Anastasiia Amari, Mangesh D. Hade, Nicholas R. Merriam, Zachary D. Schultz, Scott Q. Harper, Nizar Y. Saad, Setty M. Magaña, Willa A. Hsueh, Rachel E. Kopec, Blaise R. Kimmel, Andre F. Palmer, Eduardo Reátegui   +23 more
wiley   +1 more source

A Non-Invasive Strategy for Neonatal Alloimmune Thrombocytopenia Diagnosis: Newborn Platelet Genotyping with Buccal Swabs

International Journal of Neonatal Screening, 2016
Neonatal alloimmune thrombocytopenia results from the maternal immune response against fetal-specific antigens inherited from the father. The diagnosis is ascertained only when the maternal alloantibody and the offending antigen present in the newborn ...
Gérald Bertrand, Cécile Kaplan
doaj   +1 more source

Related donor platelet transfusion improves platelet transfusion refractoriness in hematological patients

Frontiers in Medicine, 2023
ObjectiveTransfusion of HLA-matched platelets can reduce the effect of alloimmune responses on platelet transfusion efficacy; however, finding HLA-matched platelets in the population is nearly impossible. Almost all HLA-matched platelets from related are
Jing-Cheng Zhang, Li-Hong Ni, Yan Tu, Hui-Xian Hu   +3 more
doaj   +1 more source