Results 61 to 70 of about 372,643 (301)

Transfusion of pooled buffy coat platelet components prepared with photochemical pathogen inactivation treatment: the euroSPRITE trial [PDF]

, 2003
A nucleic acid-targeted photochemical treatment (PCT) using amotosalen HCl (S-59) and ultraviolet A (UVA) light was developed to inactivate viruses, bacteria, protozoa, and leukocytes in platelet components.
van, Rhenen D, D. van Rhenen, Gulliksson, Hans, Cazenave, Jean-Pierre, Klüter, H, Klüter, Harald, Cazenave, J-P, Marblie, S, Corash, L, Buchholz, Don, Lin, Lily, Ljungman, Per, Laforet, M, Gulliksson, H, Flament, Jocelyne, Ljungman, P,, Metzel, Peyton, Laforet, Michel, Vermeij, Hans, Conlan, Maureen, de, Greef G, Pamphilon, DH, Kappers-Klunne, Mies, Pamphilon, D, Klunne, Mies, Pamphilon, Derwood, Rhenen, Dick, Lioure, B, Mayaudon, V, Lioure, Bruno, Corash, Laurence, Conlan, M, Buchholz, D, Vermeij, H, Ljungman, P, Davis, Kathryn, Greef, Georgine, Gulliksson, H,, Lin, L, Davis, K, de Greef, Georgine, Kappers-Klunne, M, Flament, J, Metzel, P, Mayaudon, Véronique, Marblie, Stephane, van Rhenen, Dick   +46 more
core   +1 more source

14‐3‐3γ Protects Against Postoperative Cognitive Dysfunction by Regulating Tau Thr205 Phosphorylation and Synaptic Integrity

Advanced Science, EarlyView.
Integrative multi‐cohort analyses identify 14‐3‐3γ as a biomarker and regulator of cognitive vulnerability. Experimental studies show that 14‐3‐3γ loss is associated with Tau Thr205 phosphorylation, synaptic dysfunction, and cognitive impairment, while genetic overexpression or pharmacological stabilization of 14‐3‐3γ confers protective effects in ...
Shouqiang Zhu, Xue Han, Heng Zhang, Chang Ye, Tianjiao Xia, Xiaoping Gu   +5 more
wiley   +1 more source

Comparison of the Effects of Apheresis and Pooled Platelet Transfusions on Platelet Count

Turkish Journal of Internal Medicine
Background: To compare the increase in platelet count after the transfusion of apheresis and pooled platelet suspensions among patients in the internal medicine intensive care unit.Methods Patients who received platelet suspension transfusions and were ...
İbrahim Halil Dikici, Esra Cengiz
doaj   +1 more source

Lusutrombopag is effective and safe in patients with chronic liver disease and severe thrombocytopenia: a multicenter retrospective study

BMC Gastroenterology, 2020
Background Chronic liver disease (CLD) is often complicated by severe thrombocytopenia (platelet count  50,000/µL at baseline: the proportions of patients who did not require platelet transfusion were 84–96%, which might be overestimated.
Hiroaki Nomoto, Naoki Morimoto, Kouichi Miura, Shunji Watanabe, Yoshinari Takaoka, Hiroshi Maeda, Takahiro Sasaki, Yohei Koyashiki, Hidekazu Kurata, Norikatsu Numao, Norio Isoda, Hironori Yamamoto   +11 more
doaj   +1 more source

A Rapid Platelet Function Assay Used to Regulate Platelet Transfusion Prophylaxis Following Cardiopulmonary Bypass Surgery

, 2023
Subsequent to cardiac surgery with cardiopulmonary bypass (CPB), patients are at risk of postoperative bleeding caused by acquired defects associated with the procedure. As such, many patients receive prophylactic blood product transfusion.
David T. Pearman, David G.M. Carville, Kathy E. Shaffer, Robert S. Galen   +3 more
core   +1 more source

Radical Resection of the Third Portion of the Duodenum for Secondary Aortoduodenal Fistula

Annals of Gastroenterological Surgery, EarlyView.
Secondary aortoduodenal fistula most commonly involves the third portion of the duodenum and requires definitive management of both vascular and gastrointestinal components. We demonstrate a step‐by‐step technique for radical duodenal resection and reconstruction performed in structured collaboration with cardiovascular surgeons.
Koji Kubota, Akira Shimizu, Tsuyoshi Notake, Tatsuichiro Seto, Yuji Soejima   +4 more
wiley   +1 more source

Prediction of Long‐Term Prognosis in Patients With Hepatocellular Carcinoma Using the National Clinical Database Risk Calculator

Annals of Gastroenterological Surgery, EarlyView.
This study aimed to determine the value of the National Clinical Database (NCD) risk calculator in predicting surgical outcomes and long‐term prognosis in patients undergoing resection for hepatocellular carcinoma (HCC). We retrospectively analyzed data from 210 patients with HCC who underwent initial hepatic resection, assessing the relationship ...
Mariko Tsukagoshi, Kenichiro Araki, Norio Kubo, Takamichi Igarashi, Shunsuke Kawai, Kei Hagiwara, Kouki Hoshino, Ryo Muranushi, Ken Shirabe   +8 more
wiley   +1 more source

Clinical observation of factors in the efficacy of blood component transfusion in patients following hematopoietic stem cell transplantation. [PDF]

PLoS ONE, 2012
BACKGROUND: Factors affecting the efficacy of platelet and red blood cell (RBC) transfusion in patients undergoing hematopoietic stem cell transplantation (HSCT) have not been studied extensively.
Xi Zhang, Yanni Xiao, Qian Ran, Yao Liu, Qianbi Duan, Huiling Duan, Xingde Ye, Zhongjun Li   +7 more
doaj   +1 more source

ABO-identical versus incompatible platelet transfusion in patients with intracranial hemorrhage.

PLoS ONE
BackgroundPatients with spontaneous and traumatic intracranial hemorrhage (ICH) are frequently transfused platelets to treat thrombocytopenia, platelet function defects, and reverse antiplatelet drugs.
Lauren K Dunn, Emily Venner, Matthew Nguyen, Jose Perdomo Trejo, Zachary Holley, Bhiken I Naik, Jenna Khan, Michael Mazzeffi   +7 more
doaj   +1 more source

Preoperative FIB‐4 Index as a Potential Factor Associated With Severe Postoperative Complications and Endogenous Organ Failure After Hepatectomy for Hepatocellular Carcinoma

Annals of Gastroenterological Surgery, EarlyView.
This study demonstrates that a preoperative FIB‐4 index ≥ 5.0 independently predicts severe complications and endogenous organ failure (EOF) following hepatectomy for hepatocellular carcinoma. By capturing structural liver fragility and systemic vulnerability, the FIB‐4 index enhances surgical risk stratification beyond traditional functional markers ...
Masanori Nakamura, Yukiyasu Okamura, Osamu Aramaki, Nao Yoshida, Yusuke Mitsuka, Hayato Abe, Shunsuke Yamagishi, Yasuhiro Okumura, Kyongsun Pak, Shinobu Masuda   +9 more
wiley   +1 more source