Results 81 to 90 of about 372,643 (301)

Amotosalen/ultraviolet A pathogen inactivation technology reduces platelet activatability, induces apoptosis and accelerates clearance

Haematologica, 2017
Amotosalen and ultraviolet A (UVA) photochemical-based pathogen reduction using the Intercept™ Blood System (IBS) is an effective and established technology for platelet and plasma components, which is adopted in more than 40 countries worldwide. Several
Simona Stivala, Sara Gobbato, Laura Infanti, Martin F. Reiner, Nicole Bonetti, Sara C. Meyer, Giovanni G. Camici, Thomas F. Lüscher, Andreas Buser, Jürg H. Beer   +9 more
doaj   +1 more source

DAMPS and complement activation in platelet concentrates that induce adverse reactions in patients.

, 2022
BACKGROUND Patients with severe thrombocytopenia due to bone marrow failure and after chemotherapy are still treated with platelet transfusions. Platelet concentrates (PC) are associated with a high incidence of adverse reactions (AR).
de Wit, Yasmin E S, Hamzeh-Cognasse, Hind, Cognasse, Fabrice, Ten Brinke, Anja, Zeerleder, Sacha Sergio   +4 more
core   +1 more source

Outcomes Following Pancreatoduodenectomy With Arterial Resection: A NSQIP Analysis Comparing Trends in Patient Selection and Outcomes to Venous or no Vascular Resection Over 5 Years

International Journal of Cancer, EarlyView.
ABSTRACT Evaluation of arterial resection (AR) during pancreatoduodenectomy (PD) remains limited. This study compares PD with AR to PD with venous resection (VR) and no vascular resection (NVR). Patient demographics, outcomes, and changes over 5 years are evaluated.
Kevin Verhoeff, Alynne Kris Ribano, Daniel Kilburn, Carol‐Anne Moulton, Chaya Shwaartz, Trevor Reichman, Ian McGlivray, Sean Cleary   +7 more
wiley   +1 more source

Chinese expert consensus on precision diagnosis, treatment, and multidisciplinary management of immune platelet transfusion refractoriness (2026 Edition)

Zhongguo shuxue zazhi
Patients with thrombocytopenia or platelet dysfunction often require platelet transfusions to improve their condition. However, some patients develop platelet transfusion refractoriness (PTR) after multiple transfusions, characterized by a lack of ...
Clinical Transfusion Medicine Professional Committee of the Chinese Society of Blood Transfusion
doaj   +1 more source

Impact of Cell Saver technology on pro‐hemostatic factors transfusion in placenta accreta spectrum interventions: A 10‐year retrospective single‐center study

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Background While Cell Saver technology effectively reduces red blood cell transfusion in the perioperative setting, its impact on the need for pro‐hemostatic factors remains unclear. The use of Cell Saver could impact the requirements of pro‐hemostatic factors.
Ilan Levy, Maud Vachette, Emma Van Der Putten, Marine Chouteau, François Goffinet, Catherine Fischer, Aude Girault, Yoann Athiel   +7 more
wiley   +1 more source

The use of light transmission aggregometry for monitoring platelet transfusion response in a small case cohort of Glanzmann thrombasthenia patients: a hypothesis-generating study

Platelets
Light transmission aggregometry (LTA) is commonly used to diagnose platelet disorders and has a specific pattern in Glanzmann thrombasthenia (GT). As there is currently no adequate test to assess the efficacy of platelet transfusion, we explored whether ...
Karlijn H.G. Rutten, Olga Tsiamita, Sean Platton, Mathieu Fiore, Rolf T. Urbanus, Suthesh Sivapalaratnam, Roger E.G. Schutgens   +6 more
doaj   +1 more source

Recombinant activated factor VIIa for severe postpartum hemorrhage in Africa: Evidence, appropriate use, and research priorities—A narrative review

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Postpartum hemorrhage (PPH) accounts for 30%–50% of maternal mortality in Africa and occurs in the context of pre‐existing anemia, limited blood product availability, delayed recognition, and constrained referral systems. Although bundle‐based care (E‐MOTIVE), early tranexamic acid (TXA), and uterotonics have substantially improved outcomes, a
Johnny Mahlangu, Haroun Rhemtula, Jarrod Zamparini, Lawrence Chauke   +3 more
wiley   +1 more source

Analysis of risk factors of ineffective platelet transfusion for leukemia and the predictive value of HLA-Ⅰ antibody and TGF-β1

Zhongguo linchuang yanjiu
Objective To analyze the risk factors of ineffective platelet transfusion in leukemia, and explore the predictive value of human leukocyte antigen (HLA)-Ⅰ antibody and transforming growth factor-β1 (TGF-β1) for ineffective platelet transfusion in ...
YAN Ling, LIU Feng, HUANG Xin
doaj   +1 more source

The Endothelial CXCR Family in Vascular Health and Disease

iNew Medicine, EarlyView.
ABSTRACT Endothelial cells (ECs) form the dynamic interface between blood and tissue, serving as key regulators of vascular homeostasis, inflammation, and repair. Among the molecular systems governing endothelial behavior, the C‐X‐C motif chemokine receptor (CXCR) family—originally characterized in immunology for its roles in leukocyte trafficking and ...
Zhiming Wu, Yandi Wu, Suowen Xu, Yu Huang, Li Wang   +4 more
wiley   +1 more source

Platelet transfusion-practice points: blood transfusion programme [Poster]

, 2012
A poster of platelet transfusion-practice points as part of the Blood Transfusion ...

core