Results 151 to 160 of about 133,426 (198)

High Intensity Interval Exercise Increases Platelet and Transforming Growth Factor‐β Yield in Platelet‐Rich Plasma

PM&R, 2020
BackgroundPlatelet‐rich plasma (PRP) is an emerging orthobiologic treatment for musculoskeletal conditions like osteoarthritis. Two studies have demonstrated the influence of longer duration exercise on PRP composition, but no study has ever explored the impact of high intensity interval exercise (HIIE) on PRP content.ObjectiveTo quantify cellular and ...
Michael R. Baria, Meghan M. Miller, James Borchers, Shannon Desmond, James Onate, Robert Magnussen, William Kelton Vasileff, David Flanigan, Christopher Kaeding, Sushmitha Durgam   +9 more
openaire   +2 more sources

Economic Impact of Donor Platelet Count and Platelet Yield in Apheresis Products: Relevance for Emerging Issues in Platelet Transfusion Therapy

Vox Sanguinis, 1999
Abstract Introduction: We analyzed donor platelet counts and platelet product yields in 708 consecutive platelet aphereses in our program in order to define the importance of this relationship for emerging issues in platelet transfusion therapy. Methods: Aphereses performed on the Spectra 3.6 (COBE, Lakewood.
L T, Goodnough, S, Ali, G, Despotis, M, Dynis, J F, DiPersio   +4 more
openaire   +2 more sources

High‐yield platelet concentrates attainable by continuous quality improvement reduce platelet transfusion cost and donor exposure

Transfusion, 1997
BACKGROUND: Donor exposure risk and cost in platelet transfusion practice can be limited by increasing the recovery of platelets from donor units.STUDY DESIGN AND METHODS: This study presents results of continuous quality improvement efforts in platelet production and compares the in vivo therapeutic efficacy of currently produced platelet concentrates
D L, Kelley, R L, Fegan, A T, Ng, M K, Kennedy, E, Blanda, L A, Chambers, M S, Kennedy, L C, Lasky   +7 more
openaire   +2 more sources

Effects of high‐yield thrombocytapheresis on the quality of platelet products

Transfusion, 2007
BACKGROUND: The steadily increasing demands for single‐donor apheresis platelet (PLT) concentrates (APCs) are a challenge to the PLT supply system. Therefore, efforts to improve plateletpheresis yield, allowing apheresis products to be split into 2 or more units, are valuable strategies. No data to demonstrate in vivo transfusion efficacy of these high‐
Friedgard, Julmy, Roland A, Ammann, Behrouz, Mansouri Taleghani, Stefano, Fontana, Andreas, Hirt, Kurt, Leibundgut   +5 more
openaire   +2 more sources

Filtration of Platelet-Poor Plasma Specimens Yields Platelet-Free Plasma: Application for Batch Analysis of Beta-Thromboglobulin and Platelet Factor 4

American Journal of Clinical Pathology, 1990
The authors investigated filtration of platelet-poor plasma through a 0.2-micron filter for the analysis of beta-thromboglobulin (beta-TG) and platelet factor 4 (PF4) in frozen specimens. Platelets were detected by electron micrograph in the platelet-poor plasma preparation without filtration.
R C, Schiebout-Clark, M C, Haven, W D, Haire, R B, Wilson, R S, Markin   +4 more
openaire   +2 more sources

Routine high-yield, low-contamination platelet concentrates produced with eccentriplate

Plasma Therapy and Transfusion Technology, 1987
In 1986 a new machine for the production of low-contamination platelet concentrates (PC) was introduced in our hemapheresis unit. In 15 months 967 procedures were carried out. There were three different phases of our study: A) the learning period, B) the research, and C) the routine application.
M. Valbonesi, R. Frisoni, P.A. Pittaluga, C. Capra, G. Lercari, L. Giuliano, G. Angelini, I. Panzani   +7 more
openaire   +1 more source

Factors affecting platelet yield and their impact on the platelet increment of patients receiving single donor PLT transfusion

Journal of Clinical Apheresis, 2007
AbstractThe aim of this study was to analyze the impact of various donor and machine parameters on PLT yield in 127 PLT apheresis procedures, to optimize PLT yield achieving clinical and economic advantages. One hundred and twenty‐seven apheresis procedures were analyzed.
A Aboul, Enein, E A, Hussein, S, El Shafie, M, Hallouda   +3 more
openaire   +2 more sources

The ‘cherry buffy‐coat syndrome’, a cause of decreased platelet yield in platelet concentrates obtained from buffy‐coats

Vox Sanguinis, 2001
Background and ObjectivesA large number of European blood centres, including our own, use the buffy‐coat method for platelet production. In this article we describe a previously unnoticed phenomenon shown by a proportion of buffy‐coats, which display an unusually bright cherry colour and low platelet counts.Materials and MethodsWe performed bacterial ...
P, Rebulla, C, Smacchia, N, Greppi, L, Porretti, R, Lopa, M, Cernuschi, G, Sirchia   +6 more
openaire   +2 more sources

MAP kinase localizes to the platelet-yielding demarcation membrane system in megakaryocytes

Blood, 2000
To the editor: MAP kinase localizes to the platelet-yielding demarcation membrane system in megakaryocytes Megakaryopoiesis and increased platelet levels are greatly promoted by the c-Mpl ligand, thrombopoietin (TPO), which binds to the c-Mpl receptor.[1][1] Among the signal transduction ...
S, Sun, C W, Jackson, K, Ravid
openaire   +2 more sources

Diminished platelet yield and enhanced platelet aggregability in platelet-rich plasma of peripheral vascular disease patients.

International angiology : a journal of the International Union of Angiology, 1995
Centrifugation of citrated whole blood (cit-WB) for platelet rich plasma (PRP) preparation resulted in a significantly diminished platelet yield compared to when blood was collected in citrate + aspirin (acetylsalicylic acid; ASA) or EDTA anticoagulants in both apparently healthy young subjects and peripheral vascular disease (PVD) patients.
M A, Barradas, G, Stansby, G, Hamilton, D P, Mikhailidis   +3 more
openaire   +1 more source