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Evaluation of donor factors contributing to plateletpheresis yields among apheresis platelet donors

Journal of Clinical Apheresis, 2013
BackgroundThe University of California, Irvine Blood Donor Center operates a plateletpheresis donor program utilizing the Amicus Cell Separator. Plateletpheresis donors may donate one or more apheresis platelet (PLT) units per collection event. This study seeks to characterize UC Irvine's donor pool by identifying biometric and demographic attributes ...
William J, Woodall   +2 more
openaire   +2 more sources

The relationship of platelet yield, donor’s characteristic and apheresis instruments in China

Transfusion and Apheresis Science, 2013
Platelet yield was associated with donor's characteristic and property of apheresis instruments. Here, we have analyzed the relationship of platelet yield, physiologic parameters of donors for different apheresis instruments in China. Data were consecutively retrieved from plateletapheresis donors during March 1, 2007 and March 1, 2012. Three different
Guomei, Yin   +5 more
openaire   +2 more sources

Blood drive: Improving the yields of platelet cell manufacturing

Science Translational Medicine, 2019
Controlling oxygenation, media conditions, and CD34 + cell seeding density in gas-permeable bioreactors improve megakaryocyte yields.
openaire   +1 more source

A Critical Review of Platelet Yield by Haemonetics 30®.

Scandinavian Journal of Haematology, 1981
By means of a Haemonetics 30 cell separator platelets were collected for transfusion purposes from 18 different blood donors. A median yield of 5.7 times 1011 platelets was obtained. The yield of platelets was found to be linearly related to the donors' initial platelet counts.
J, Rosenkvist   +3 more
openaire   +2 more sources

Minor diurnal and activity-induced variations in daytime peripheral blood platelet counts do not have any major impact on platelet yield by platelet apheresis

Transfusion and Apheresis Science, 2010
Physical activity alters systemic levels of several angioregulatory cytokines that affect microvascular endothelial cells and can be assumed to influence vascular permeability. This may alter platelet release to the bone marrow microcirculation and thereby the levels of circulating platelets.
Ciğdem Akalin, Akkök   +6 more
openaire   +2 more sources

Effect of Eptifibatide for Acute Coronary Syndromes: Rapid Versus Late Administration—Therapeutic Yield on Platelets (The EARLY Platelet Substudy)

Journal of Thrombosis and Thrombolysis, 2002
Receptors other than GP IIb/IIIa may mediate leukocyte-platelet-endothelial interactions that obstruct the microvasculature in acute coronary syndromes (ACS) and cause microinfarcts. The effect of eptifibatide on these receptors was investigated in a substudy of the EARLY Trial.Patients received early (in the Emergency Department, n = 27) or late (12 ...
Paul A, Gurbel   +8 more
openaire   +2 more sources

Platelet Monoamine Oxidase and Plasma Amine Oxidase: Effect of Anticoagulant and Centrifugation Technique on Platelet Yield and Enzyme Activity

Neuropsychobiology, 1983
Platelet recovery and activity of platelet monoamine oxidase (MAO) and plasma amine oxidase (PAO) were determined using different centrifugation procedures (125 g for 15 min vs. 600 g for 2.5 min) and anticoagulants. With either centrifugation procedure, the use of ethylenediaminetetraacetate (EDTA) as anticoagulant resulted in higher platelet yields ...
M, Baron, M, Levitt, R, Gruen
openaire   +2 more sources

Factors influencing yield of platelet aphaeresis using continuous flow cell separator

International Journal of Medical Science and Public Health, 2013
Background: In Transfusion Medicine, screening for suitable donor for platelet aphaeresis is difficult and time consuming procedure. This might lead to delayed supply of life saving Single Donor Platelet to critically bleeding patient. Aims & Objective: The aim of this study was to analyse the effect of various donor and procedure related parameters
Jitendra Patel   +4 more
openaire   +1 more source

Reduced use of allogeneic platelets through high‐yield perioperative autologous plateletpheresis and reinfusion

Transfusion, 2013
BackgroundIntraoperative autologous platelet (PLT) collection as part of a multimodal blood conservation program carries a Class IIa recommendation from the Societies of Thoracic Surgeons and Cardiovascular Anesthesiologists, but achieving a suitable PLT yield limits its application.
Melissa, Alberts   +8 more
openaire   +2 more sources

Pre-apheresis donor platelet count: An important platelet yield predictor

Journal of Clinical Apheresis, 2006
Karan Saluja   +3 more
openaire   +1 more source

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