Results 11 to 20 of about 8,497,511 (124)
Cancer Cell International, 2023 Background Limited benefit population of immunotherapy makes it urgent to select effective biomarkers for screening appropriate treatment population. Herein, we have investigated the predictive values of circulating CD8^+ T cells and CD8^+T/CD4^+T cell ...
Jiang Liu +8 more
semanticscholar +1 more source
The ratio of nicotinic acid to nicotinamide as a microbial biomarker for assessing cell therapy product sterility. [PDF]
, 2022 Controlling microbial risks in cell therapy products (CTPs) is important for product safety. Here, we identified the nicotinic acid (NA) to nicotinamide (NAM) ratio as a biomarker that detects a broad spectrum of microbial contaminants in cell cultures ...
Barone, PW +7 more
core +1 more source
A pan-cancer single-cell transcriptional atlas of tumor infiltrating myeloid cells.
Cell, 2021 Tumor-infiltrating myeloid cells (TIMs) are key regulators in tumor progression, but the similarity and distinction of their fundamental properties across different tumors remain elusive.
Si Cheng +19 more
semanticscholar +1 more source
Cell Death and Disease, 2020 A successful pregnancy requires sophisticated regulation of uterine microenvironment to guarantee the existence of semi-allogeneic conceptus without immune rejection. T follicular regulatory (Tfr) cells exert a suppressive effect on Tfh-cell expansion, B-
Wei-Hong Zeng +10 more
semanticscholar +1 more source
Annals of Pathology and Laboratory Medicine, 2018 Background: The study was performed to analyse PVI such as mean platelet volume (MPV), platelet distribution width (PDW) and plateletlarge cell ratio (P-LCR) that are useful for identifying large and haemostatically active platelets, which are risk ...
K. Desai, Nayana R Lakum
semanticscholar +1 more source
A major role for CD4+ T cells in driving cytokine release syndrome during CAR T cell therapy
Cell Reports Medicine, 2023 Summary Anti-CD19 chimeric antigen receptor (CAR) T cell therapy represents a breakthrough for the treatment of B cell malignancies. Yet, it can lead to severe adverse events, including cytokine release syndrome (CRS), which may require urgent clinical ...
M. Boulch +12 more
semanticscholar +1 more source
Hardware implementation of Modified Annular Ring Ratio for Blood Cell Detection in Thin Blood Smear Images [PDF]
, 2018 Malaria continues to spread in endemic areas. This deadly disease is the subject of multiple researches in terms of patient diagnoses. Post treatment diagnoses are necessary to make sure that patients treated for malaria continue to be free from ...
Stecowiat, A., Reni, S., Kale, I.
core +1 more source
Assessment of Platelet Indices as Prognostic Markers in Seropositive Cases of Dengue
Journal of Medical Science And clinical Research, 2019 Background: Dengue fever is the most prevalent arboviral disease globally and an increasing number of cases are being reported every year. The assessment of platelet count and platelet indices at an early stage in the disease helps to predict the ...
S. Indumathi
semanticscholar +1 more source
Cancer Cell, 2022 Platinum-based chemotherapy is the standard first-line treatment for advanced esophageal squamous cell carcinoma (ESCC). In this phase 3 study (ClinicalTrial.gov: NCT03829969), 514 patients with treatment-naïve advanced ESCC were randomized (1:1) to ...
Zi-Xian Wang +80 more
semanticscholar +1 more source
Cancer Cell, 2023 Combining immunotherapy with chemotherapy can provide improved survival in advanced squamous non-small-cell lung cancer (NSCLC) patients without targetable gene alterations.
Cai-Cun Zhou +25 more
semanticscholar +1 more source