Results 211 to 220 of about 527,915 (318)

Improvement of Hemocompatibility in Passive Cardiovascular Implant Devices

Advanced Therapeutics, EarlyView.
With the ever‐increasing reliance on cardiovascular devices and implants, minimizing their impact on blood is vital for their continued success. This review investigates the common methods of tackling this challenge through careful selections of material and surface modifications.
Shiyen L. Perera, Christoph E. Hagemeyer, Julian A. Smith, Josie Carberry, Be'eri Niego   +4 more
wiley   +1 more source

Resveratrol as a Potential Platelet Inhibitor in Aspirin-Resistant Diabetic Patients-A Novel Therapeutic Strategy Targeting F₀F₁-ATP Synthase Inhibition. [PDF]

Life (Basel)
Panfoli I, Carlini L.
europepmc   +1 more source

Therapeutic Antibodies for Mosquito‐Borne Orthoflavivirus Infections: Discovery, Engineering Approaches, and Advances in mRNA‐Based Delivery Systems

Advanced Therapeutics, EarlyView.
This review explores how antibody engineering and display technologies are driving therapeutic advances against mosquito‐borne orthoflaviviruses such as Zika, dengue, and yellow fever viruses. It highlights diverse neutralizing targets on the envelope protein, including the conserved fusion loop, and discusses how Fc engineering, rational antigen ...
Ana Clara Barbosa Antonelli, Lucas Silva Rodrigues, Maria Clara Moura Pinheiro, Sylvia Barbosa Pinhate, Marcelo de Macedo Brígido, Andréa Queiroz Maranhão   +5 more
wiley   +1 more source

Platelet bioenergetics correlate with skeletal muscle respiration in a murine model of type II diabetes. [PDF]

Front Mol Biosci
Wilkinson MS, Ferguson EJ, Bureau J, Haggerty-Goede RAL, Miller DM, Kuriakose M, Veeneman JLMH, Lima PDA, McGlory C, Dunham-Snary KJ.   +9 more
europepmc   +1 more source

Super‐Convergent Meshless Computations for Active Vibration Control of Bi‐Directional Functionally Graded Terfenol‐D Beams with Twisted Geometry

Advanced Theory and Simulations, EarlyView.
This study develops a superconvergent meshless method to analyze and control vibrations in twisted, bidirectional functionally graded Terfenol‐D beams. By optimizing magnetostrictive patch placement, it demonstrates effective vibration suppression under dynamic loads, highlighting the design potential of strategically graded materials in complex ...
Mukund A. Patil, Tanmoy Mukhopadhyay, Susmita Naskar   +2 more
wiley   +1 more source

Mitochondrial respiratory function in human platelets: Influence of sample preparation, assay buffer, and instrumental platform. [PDF]

Physiol Rep
Porter C, Treas L, Pavliv O, Sadler D, Cotter M, Rose S, Børsheim E, Diaz Fuentes EC.   +7 more
europepmc   +1 more source

Multiomics Analyses Reveal an Essential Role of Tryptophan in Treatment of csDMARDs in Rheumatoid Arthritis

Advanced Science, EarlyView.
Rheumatoid arthritis is a disease characterized by joint inflammation. Approximately 50% of patients show insufficient response to traditional synthetic disease‐modifying antirheumatic drugs. This study aims to elucidate differential molecular profiles of the mechanisms underlying drug responses through multi‐omics strategy.
Congcong Jian, Jing Zhu, Jianhong Wu, Yan Zhang, Jianghua Chen, Huan Wang, Hengyan Liu, Ke Xu, Jiaxin Huang, Xiaoting Zhu, Yuanli Wei, Shilin Li, Tingting Wang, Xuan Huang, Qinghua Zou, Jie Zhang, Jiang Su, Xinming Du, Yaping Lu, Tianci Zhou, Yingtong Zhou, Minglong Tang, Bin Li, Xue Zhou, Qihao Wei, Qiulong Yan, Fanxin Zeng   +26 more
wiley   +1 more source

NADPH oxidase 2 inhibitor GSK2795039 exerts antiplatelet and antithrombotic activity. [PDF]

Sci Rep
Oh EB, Kong YJ, Kim T, Jang J, Yu H, Park JW, Kim S, Kim T, Sohn J, Chang TS.   +9 more
europepmc   +1 more source

Integrin α8‐Mediated Pericyte Morphogenesis Controls Blood‐Brain Barrier Integrity

Advanced Science, EarlyView.
This study highlights that ITGA8 impacts pericyte morphology and function, both crucial for BBB integrity, via RhoA/ROCK signaling, thus influencing TGF‐β1 activation through cytoskeletal tension and ECM interactions. Notably, in post‐ischemic recovery models, ITGA8 deficiency exacerbates vascular dysfunction by impairing pericyte‐mediated BBB ...
Chang‐Xiong Gong, Lin‐Lin Hu, Ling Jiang, Pei‐Xia Shi, Shuang Zhang, Yuan Zhao, Bing‐Qiao Wang, Xiao‐Feng Cheng, Cheng‐Kang He, Sen Lin, Yue Dai, Zhao‐You Meng, Chen‐Hao Zhao, Bao‐Liang Sun, Qi Xie, Fang‐Fei Li, Qing‐Wu Yang   +16 more
wiley   +1 more source

Diabetic Platelets: Pathophysiology, Clinical Significance, and Therapeutic Perspectives. [PDF]

Diabetes Ther
Sharma N, Verma SK, Sharma S, Kapoor N, Kalra S.   +4 more
europepmc   +1 more source