Results 191 to 200 of about 373,549 (269)

Thermochemical Micro‐Explosion for Prompt Thrombolysis via Proximal Injection of Liquid Alkali Metal

Advanced Science, EarlyView.
We report a micro‐explosive thermochemical thrombolysis (METCT) therapy via injectable liquid alkali metal encapsulated in dimethyl silicone (LAM@oil). METCT enables prompt and safe vascular recanalization within 90 s. Critically, the LAM@oil system demonstrates significantly higher thrombolytic efficacy compared to clinically available thrombolytic ...
Xin Liao, Yi Hou, Jie Zhang, Bo Wang, Minghui Guo, Hua Qu, Wei Rao, Jing Liu   +7 more
wiley   +1 more source

Immature platelets: A useful tool for thrombocytopenia etiology classification in adults. [PDF]

Hematol Transfus Cell Ther
Pimentel RF, Leal Dos Santos TR, Bezerra MAC, Hatzlhofer BLD, Muniz MTC.   +4 more
europepmc   +1 more source

Data‐Driven Modeling of Composition–Processing–Microstructure Relations for Recycled Aluminum Cast Alloys

Advanced Science, EarlyView.
Interpretable machine learning reveals how composition and processing govern the formation and microstructural burden of Fe‐rich intermetallic compounds in recycled Al–Si–Fe–Mn alloys. By separating morphology selection from morphology‐conditioned burden partitioning, this framework shows that identical Fe contents can yield different intermetallic ...
Jaemin Wang, Waleed Mohammed, Dierk Raabe   +2 more
wiley   +1 more source

Platelets cause microvascular occlusion and delayed neurological deficits after subarachnoid hemorrhage in mice. [PDF]

Exp Mol Med
Dienel A, Hong SH, Torres K, Matsumura K, Guzman J, Thankamani Pandit P, Samal B, Kaur H, Nemirajaiah S, Bernal A, Choi HA, McCullough LD, Blackburn SL, Aronowski J, McBride DW.   +14 more
europepmc   +1 more source

PIEZO1 is Required for Acute Myeloid Leukemia Progression and Leukemia Stem Cell Maintenance via HIF1A‐SLC7A11 Axis‐Mediated Ferroptosis Defense

Advanced Science, EarlyView.
This study identifies the mechanosensor PIEZO1 as a key factor in promoting acute myeloid leukemia progression and uncovers a ferroptosis defense system mediated by PIEZO1‐HIF1A‐SLC7A11 axis that is essential for leukemia stem cell maintenance. This ferroptotic defense system may represent a unique vulnerability for leukemia stem cells, providing a ...
Tiantian Zhang, Ziyan Cao, Kexin Gao, Shuxin Yao, Yanbing Zheng, Manman Cui, Rong Yin, Guoqiang Han, Jin Hu, Chengyi Wang, Haojian Zhang   +10 more
wiley   +1 more source

Platelet-mediated progression of fatty liver disease in metabolic dysfunction-associated steatohepatitis: a pathophysiological review. [PDF]

Front Med (Lausanne)
Alhawiti NM.
europepmc   +1 more source

Multi‐Axis Stretchable Zippers for Personalized Wound Healing

Advanced Science, EarlyView.
Multi‐axis stretchable zippers can adapt to complex wound morphologies and enable personalized wound treatment through programmable contraction. This morphological matching strategy helps accelerate wound closure, improve blood perfusion, promote epithelial regeneration, and enhance collagen remodeling, pioneering new directions for personalized and ...
Siyuan Cai, Guang Yao, Zijian Chen, Shiqi Zhou, Peisi Li, Liheng Lin, Huake Yang, Ziyi Zhou, Linbo Jin, Xingyi Gan, Chenzheng Zhou, Zhen Cai, Taisong Pan, Min Gao, Dongli Fan, Yuan Lin, Yiming Zhang   +16 more
wiley   +1 more source

Ex vivo effects of low dose delayed release rapamycin on agonist-induced platelet aggregation, activation and procoagulant platelet phenotypes in domestic cats. [PDF]

Sci Rep
Shaverdian M, Nguyen N, Fitzgerald S, Grubb L, Stern JA, Li RHL.   +5 more
europepmc   +1 more source

Predictive Value of Neutrophils, Lymphocytes, Platelets, Neutrophil-Lymphocyte Ratio (NLR), and Platelets-Lymphocyte Ratio (PLR) in Preterm Labor: Single and Combined Indices. [PDF]

Obstet Gynecol Int
Elmaradny E, Aman S, Alaskar M, Alnefayi R, Almuhesseny A, Alshreef H, Alshammari M, Alhazmi A, Altraifi L, AlSaedi A.   +9 more
europepmc   +1 more source

Platelets Orchestrate a Neuroimmune Axis Driving Cutaneous Inflammation and Itch. [PDF]

Research (Wash D C)
Hu X, Wang F, Wang T, Liu Y, Zhang L, Liu L, Cao L, Pu S, Yang R, Feng J.   +9 more
europepmc   +1 more source