Results 91 to 100 of about 3,387,841 (331)

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Parametric Analysis of Tensegrity Plate-Like Structures: Part 1—Qualitative Analysis [PDF]

, 2020
Paulina Obara, Justyna Tomasik
openalex   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source

Study of the effect of composite constrained layers in vibration damping of plates

International Journal of Applied Mechanics and Engineering, 2014
To add damping to the system, viscoelastic materials (VEM) are added to structures, in order to enhance damping effects of the VEM, a constraining layer is attached. Due to the addition of the material on the system the fundamental characteristics of the
K.S.K. Sasikumar, S. Selvakumar, K.P. Arulshri   +2 more
doaj   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

Molecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian, Sriraam Sivachandran, Melissa Galati, Brandon Ramchatesingh, Hibo Rijal, Johnny Hanna, Elena Netchiporouk, May Chergui, Margaret Redpath, Samy Abou Setah, Ivan V. Litvinov   +10 more
wiley   +1 more source

Radiation force on a single atom in a cavity [PDF]

We consider the radiation pressure microscopically. Two perfectly conducting plates are parallelly placed in a vacuum. As the vacuum field hits the plates they get pressure from the vacuum.
Kim, M. S.
core   +1 more source

The S shape of a granular pile in a rotating drum

, 2006
The shape of a granular pile in a rotating drum is investigated. Using Discrete Elements Method (DEM) simulations we show that the "S shape" obtained for high rotation speed can be accounted for by the friction on the end plates.
A. Caprihan, D. Frenkel, D. Khakhar, D. Khakhar, E. John Hinch, GdR-MiDi, H. Henein, M. Nakagawa, M. Renouf, N. Taberlet, Nicolas Taberlet, Patrick Richard   +11 more
core   +2 more sources

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source

A microscopic model for Josephson currents

, 2003
A microscopic model of a Josephson junction between two superconducting plates is proposed and analysed. For this model, the nonequilibrium steady state of the total system is explicitly constructed and its properties are analysed.
A Verbeure, Anderson P W, Aschbacher W H, Fannes M, Goderis D, J Lauwers, Jak?i? V, Lauwers J, Likharev K K, Ruelle D, Sewell G L, Thirring W, Thirring W   +12 more
core   +1 more source

A projected super-penalty method for the $$C^1$$-coupling of multi-patch isogeometric Kirchhoff plates [PDF]

, 2021
Luca Coradello, Gabriele Loli, Annalisa Buffa   +2 more
openalex   +1 more source