Results 81 to 90 of about 1,726,143 (317)

THE BOOK BY G.R. FOULGER: FROM MELTING ANOMALIES TO HYPOTHESES ON PLATES OR PLUMES?

open access: yesГеодинамика и тектонофизика, 2015
The book «Plates vs. plumes: a geological controversy» (Fig. 1) is intended for the advanced student who is not satisfied by the presentday interpretation of intraplate volcanism.
Sergei V. Rasskazov
doaj   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, Volume 20, Issue 6, Page 1513-1534, June 2026.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Bounds on the effective isotropic moduli of thin elastic composite plates

open access: yesArchives of Mechanics, 2010
The main aim of this paper is to estimate the effective moduli of an isotropic elastic composite, analyzed within the framework of the Kirchhoff-Love theory of thin plates in bending.
G. Dzierżanowski
doaj   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, Volume 20, Issue 6, Page 1591-1611, June 2026.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

The analysis of deformation states high strength fibre-reinforced concrete plates in flexural

open access: yesBudownictwo i Architektura, 2012
The article presents the results of bending tests on reinforced concrete made of high strength concrete with water/(cement+microsilica) ratio of 0.2 with addition of steel and polypropylene fibres obtained with the system of non-contact three-dimensional
Piotr Smarzewski   +2 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

The effect of boundary conditions on the failure of thin plates subjected to impulsive loading

open access: yes, 1995
Bibliography: leaves 64-65.This report presents the results of an investigation into the effects of edge boundary conditions on the failure of thin plates subjected to impulsive loading.
Thomas, B M
core  

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

open access: yesMolecular Oncology, Volume 20, Issue 6, Page 1612-1625, June 2026.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli   +7 more
wiley   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, Volume 20, Issue 6, Page 1494-1512, June 2026.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Incompatible Deformations in Hyperelastic Plates

open access: yesMathematics
The design of thin-walled structures is commonly based on the solutions of linear boundary-value problems, formulated within well-developed theories for elastic plates and shells.
Sergey Lychev   +3 more
doaj   +1 more source

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